1SO7
 
 | | Maltose-induced structure of the human cytolsolic sialidase Neu2 | | 分子名称: | CHLORIDE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Kato, R, Monti, E, Wakatsuki, S. | | 登録日 | 2004-03-12 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
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2IEZ
 | | Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group | | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-27B | | 著者 | Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S. | | 登録日 | 2006-09-19 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
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2IEY
 | | Crystal Structure of mouse Rab27b bound to GDP in hexagonal space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-27B | | 著者 | Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S. | | 登録日 | 2006-09-19 | | 公開日 | 2007-05-01 | | 最終更新日 | 2012-04-11 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
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1SNT
 | | Structure of the human cytosolic sialidase Neu2 | | 分子名称: | Sialidase 2 | | 著者 | Chavas, L.M.G, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Kato, R, Monti, E, Wakatsuki, S. | | 登録日 | 2004-03-12 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
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2IF0
 | | Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-27B | | 著者 | Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S. | | 登録日 | 2006-09-19 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
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3BC1
 | | Crystal Structure of the complex Rab27a-Slp2a | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-27A, ... | | 著者 | Chavas, L.M.G, Ihara, K, Kawasaki, M, Wakatsuki, S. | | 登録日 | 2007-11-12 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a
Structure, 16, 2008
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1VCU
 | | Structure of the human cytosolic sialidase Neu2 in complex with the inhibitor DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | | 著者 | Chavas, L.M.G, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Kato, R, Monti, E, Wakatsuki, S. | | 登録日 | 2004-03-12 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
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2F10
 | | Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor | | 分子名称: | 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, PHOSPHATE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, McKimm-Breschkin, J, Colman, P.M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor
To be Published
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2F13
 | | Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor | | 分子名称: | (2R)-2,3-dihydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor
To be Published
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2F11
 | | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor | | 分子名称: | 2-methylpropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor
To be Published
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2F26
 | | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant | | 分子名称: | CHLORIDE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant
To be Published
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2F0Z
 | | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor | | 分子名称: | Sialidase 2, ZANAMIVIR | | 著者 | Chavas, L.M.G, Kato, R, McKimm-Breschkin, J, Colman, P.M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor
To be Published
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2F25
 | | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor
To be Published
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2F24
 | | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant | | 分子名称: | CHLORIDE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q Mutant
To be Published
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2F29
 | | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.921 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor
To be Published
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2F12
 | | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor | | 分子名称: | 3-hydroxypropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-14 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor
To be Published
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2F28
 | | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant | | 分子名称: | CHLORIDE ION, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 Q116E Mutant
To be Published
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2F27
 | | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Sialidase 2 | | 著者 | Chavas, L.M.G, Kato, R, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | | 登録日 | 2005-11-15 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor
To be Published
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7BKX
 | | Diploptera punctata inspired lipocalin-like Milk protein expressed in Saccharomyces cerevisiae | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Banerjee, S, Kanagavijayan, D, Subramanian, R, Santhakumari, P.R, Chavas, L.M.G, Ramaswamy, S. | | 登録日 | 2021-01-17 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of recombinantly expressed cockroach Lili-Mip protein in glycosylated and deglycosylated forms.
Biochim Biophys Acta Gen Subj, 1866, 2022
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5KV9
 | | Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex | | 分子名称: | 1,2-ETHANEDIOL, 2,6-anhydro-3,4,5-trideoxy-5-[(2-methylpropanoyl)amino]-4-(4-phenyl-1H-1,2,3-triazol-1-yl)-D-glycero-D-galacto-non-2-en onic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Dirr, L, El-Deeb, I.M, Chavas, L.M.G, Guillon, P, von Itzstein, M. | | 登録日 | 2016-07-13 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.
Sci Rep, 7, 2017
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5KV8
 | | Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex | | 分子名称: | 1,2-ETHANEDIOL, 2,6-anhydro-3,4,5-trideoxy-4-[4-(methoxymethyl)-1H-1,2,3-triazol-1-yl]-5-[(2-methylpropanoyl)amino]-D-glycero-D-galacto -non-2-enonic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | | 著者 | Dirr, L, El-Deeb, I.M, Chavas, L.M.G, Guillon, P, von Itzstein, M. | | 登録日 | 2016-07-13 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.
Sci Rep, 7, 2017
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7QBV
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-adenosyl-L-homocysteine bound. | | 分子名称: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBU
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBS
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, S-adenosyl-L-methionine, and peptide bound. | | 分子名称: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | 著者 | Bernardo-Garcia, N, Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2022-02-23 | | 実験手法 | X-RAY DIFFRACTION (2.327 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBT
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, FE (III) ION, ... | | 著者 | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | 登録日 | 2021-11-19 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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