5KV9

Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex

Summary for 5KV9

• Entry DOI: 10.2210/pdb5kv9/pdb
• Related: 4XJQ 4XJR 5KV8
• Descriptor: Hemagglutinin-neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: haemagglutinin-neuraminidase, hyrdrolase, viral protein, host cell surface receptor binding, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Human parainfluenza virus 3
• Total number of polymer chains: 1
• Total formula weight: 50386.00

Authors

Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,von Itzstein, M. (deposition date: 2016-07-13, release date: 2017-07-12, Last modification date: 2023-10-04)

• Primary citation: Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,Itzstein, M.V.; The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.; Sci Rep, 7:4507-4507, 2017; PubMed: 28674426; DOI: 10.1038/s41598-017-04656-y

Experimental method

X-RAY DIFFRACTION (2 Å)