5KV8
Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex
Summary for 5KV8
Entry DOI | 10.2210/pdb5kv8/pdb |
Related | 4XJQ 4XJR 5KV9 |
Descriptor | Hemagglutinin-neuraminidase, GLYCEROL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | haemagglutinin-neuraminidase, hydrolase, viral protein, host cell surface receptor binding, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Human parainfluenza virus 3 |
Total number of polymer chains | 2 |
Total formula weight | 101792.73 |
Authors | Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,von Itzstein, M. (deposition date: 2016-07-13, release date: 2017-07-12, Last modification date: 2023-10-04) |
Primary citation | Dirr, L.,El-Deeb, I.M.,Chavas, L.M.G.,Guillon, P.,Itzstein, M.V. The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design. Sci Rep, 7:4507-4507, 2017 Cited by PubMed: 28674426DOI: 10.1038/s41598-017-04656-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.949 Å) |
Structure validation
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