5KV8
Crystal structure of a hPIV haemagglutinin-neuraminidase-inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Hemagglutinin-neuraminidase | polymer | 437 | 48910.5 | 2 | UniProt (G8G134) Pfam (PF00423) | Human parainfluenza virus 3 | |
| 2 | C, D, E, L, N... (A, B) | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NDG) | |||
| 3 | F, Q (A, B) | beta-D-mannopyranose | non-polymer | 180.2 | 2 | Chemie (BMA) | |||
| 4 | G, R (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | H, S (A, B) | 2,6-anhydro-3,4,5-trideoxy-4-[4-(methoxymethyl)-1H-1,2,3-triazol-1-yl]-5-[(2-methylpropanoyl)amino]-D-glycero-D-galacto -non-2-enonic acid | non-polymer | 414.4 | 2 | Chemie (6Y6) | |||
| 6 | I, J, K, T, U... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | M (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 8 | W (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 9 | Y (B) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) | |||
| 10 | Z (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 11 | AA, BA (A, B) | water | water | 18.0 | 645 | Chemie (HOH) |
Sequence modifications
A, B: 142 - 572 (UniProt: G8G134)
| PDB | External Database | Details |
|---|---|---|
| His 573 | - | expression tag |
| His 574 | - | expression tag |
| His 575 | - | expression tag |
| His 576 | - | expression tag |
| His 577 | - | expression tag |
| His 578 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97820.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3971.8 | |
| All* | Total formula weight | 101792.7 |
