7QBU

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.

Summary for 7QBU

• Entry DOI: 10.2210/pdb7qbu/pdb
• Descriptor: Methyl coenzyme M reductase-arginine methyltransferase Mmp10, IRON/SULFUR CLUSTER, FE (III) ION, ... (8 entities in total)
• Functional Keywords: radical sam, b12 binding, methyltransferase, sp3 carbon methylation, metal binding protein
• Biological source: Methanosarcina acetivorans
• Total number of polymer chains: 2
• Total formula weight: 100286.34

Authors

Fyfe, C.D.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. (deposition date: 2021-11-19, release date: 2022-02-02, Last modification date: 2024-01-31)

• Primary citation: Fyfe, C.D.,Bernardo-Garcia, N.,Fradale, L.,Grimaldi, S.,Guillot, A.,Brewee, C.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O.; Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.; Nature, 602:336-342, 2022; PubMed: 35110733; DOI: 10.1038/s41586-021-04355-9

Experimental method

X-RAY DIFFRACTION (2.298 Å)