7QBU

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Methyl coenzyme M reductase-arginine methyltransferase Mmp10	polymer	436	47964.9	2	UniProt (A0A832SFM5) Pfam (PF19238) UniProt (by SIFTS) (Q8THG6)	Methanosarcina acetivorans
2	C, I (A, B)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
3	D, J (A, B)	FE (III) ION	non-polymer		55.8	2	Chemie (FE)
4	E, K (A, B)	5'-DEOXY-5'-METHYLTHIOADENOSINE	non-polymer		297.3	2	Chemie (MTA)
5	F, L (A, B)	CO-METHYLCOBALAMIN	non-polymer		1344.4	2	Chemie (COB)
6	G, M (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	H, N (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
8	O, P (A, B)	water	water		18.0	341	Chemie (HOH)

Sequence modifications

A, B: 1 - 411 (UniProt: A0A832SFM5)

PDB	External Database	Details
Met -24	-	initiating methionine
Ala -23	-	expression tag
Ser -22	-	expression tag
Trp -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
Pro -18	-	expression tag
Gln -17	-	expression tag
Phe -16	-	expression tag
Glu -15	-	expression tag
Lys -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95929.7
Non-Polymers*	Number of molecules	12
	Total formula weight	4356.6
All*	Total formula weight	100286.3

*Water molecules are not included.