7QBU
B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Methyl coenzyme M reductase-arginine methyltransferase Mmp10 | polymer | 436 | 47964.9 | 2 | UniProt (A0A832SFM5) Pfam (PF04055) UniProt (by SIFTS) (Q8THG6) | Methanosarcina acetivorans | |
| 2 | C, I (A, B) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
| 3 | D, J (A, B) | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) PubChem (29936) | |||
| 4 | E, K (A, B) | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 2 | Chemie (MTA) PubChem (149) PubChem (25322898) PubChem (40467850) PubChem (44264468) PubChem (46874793) PubChem (51397471) PubChem (57104771) PubChem (58108938) PubChem (58682801) PubChem (439176) PubChem (59099797) PubChem (51397472) PubChem (688097) PubChem (99302) PubChem (453683) PubChem (91614589) PubChem (98100246) PubChem (6541356) PubChem (124300729) PubChem (124300795) PubChem (13101165) PubChem (13101166) PubChem (134694842) PubChem (138107656) PubChem (164077596) | |||
| 5 | F, L (A, B) | CO-METHYLCOBALAMIN | non-polymer | 1344.4 | 2 | Chemie (COB) | |||
| 6 | G, M (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 7 | H, N (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 8 | O, P (A, B) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 411 (UniProt: A0A832SFM5)
| PDB | External Database | Details |
|---|---|---|
| Met -24 | - | initiating methionine |
| Ala -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Trp -21 | - | expression tag |
| Ser -20 | - | expression tag |
| His -19 | - | expression tag |
| Pro -18 | - | expression tag |
| Gln -17 | - | expression tag |
| Phe -16 | - | expression tag |
| Glu -15 | - | expression tag |
| Lys -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95929.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4356.6 | |
| All* | Total formula weight | 100286.3 |
