2F10

Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor

Summary for 2F10

• Entry DOI: 10.2210/pdb2f10/pdb
• Related: 1SNT 1SO7 1VCU 2F0Z 2F11 2F12 2F13 2F24 2F25 2F26 2F27 2F28 2F29
• Descriptor: Sialidase 2, PHOSPHATE ION, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, ... (4 entities in total)
• Functional Keywords: sialidase, neuraminidase, influenza virus, peramivir, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q9Y3R4
• Total number of polymer chains: 1
• Total formula weight: 42842.98

Authors

Chavas, L.M.G.,Kato, R.,McKimm-Breschkin, J.,Colman, P.M.,Fusi, P.,Tringali, C.,Venerando, B.,Tettamanti, G.,Monti, E.,Wakatsuki, S. (deposition date: 2005-11-14, release date: 2006-11-21, Last modification date: 2023-10-25)

• Primary citation: Chavas, L.M.G.,Kato, R.,McKimm-Breschkin, J.,Colman, P.M.,Fusi, P.,Tringali, C.,Venerando, B.,Tettamanti, G.,Monti, E.,Wakatsuki, S.; Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)