7QBV
B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-adenosyl-L-homocysteine bound.
Summary for 7QBV
Entry DOI | 10.2210/pdb7qbv/pdb |
Related | 7QBS 7QBT 7QBU |
Descriptor | Methyl coenzyme M reductase-arginine methyltransferase Mmp10, IRON/SULFUR CLUSTER, FE (III) ION, ... (7 entities in total) |
Functional Keywords | radical sam, b12 binding, methyltransferase, sp3 carbon methylation, metal binding protein |
Biological source | Methanosarcina acetivorans |
Total number of polymer chains | 4 |
Total formula weight | 200496.51 |
Authors | Fyfe, C.D.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. (deposition date: 2021-11-19, release date: 2022-02-02, Last modification date: 2024-01-31) |
Primary citation | Fyfe, C.D.,Bernardo-Garcia, N.,Fradale, L.,Grimaldi, S.,Guillot, A.,Brewee, C.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase. Nature, 602:336-342, 2022 Cited by PubMed: 35110733DOI: 10.1038/s41586-021-04355-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.701 Å) |
Structure validation
Download full validation report