7K09
 
 | | Puromycin N-acetyltransferase in complex with acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, Puromycin N-acetyltransferase | | 著者 | Caputo, A.T, Newman, J, Adams, T.E, Peat, T.S. | | 登録日 | 2020-09-03 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.313 Å) | | 主引用文献 | Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
Sci Rep, 11, 2021
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5F0E
 | | Murine endoplasmic reticulum alpha-glucosidase II | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2015-11-27 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5H9O
 | | Complex of Murine endoplasmic reticulum alpha-glucosidase II with D-Glucose | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2015-12-29 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HJO
 | | Murine endoplasmic reticulum alpha-glucosidase II with bound substrate analogue | | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-alpha-D-arabino-hexopyranose-(1-3)-D-glucal, ACETATE ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-01-13 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HJR
 | | Murine endoplasmic reticulum alpha-glucosidase II with bound covalent intermediate | | 分子名称: | 1,2-ETHANEDIOL, 5-fluoro-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-01-13 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IEG
 | | Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DIMETHYL SULFOXIDE, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-02-25 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.822 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IEF
 | | Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin | | 分子名称: | (2R,3R,4R,5S)-1-BUTYL-2-(HYDROXYMETHYL)PIPERIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-02-25 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IEE
 | | Murine endoplasmic reticulum alpha-glucosidase II with 1-deoxynojirimycin | | 分子名称: | 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-02-25 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IED
 | | Murine endoplasmic reticulum alpha-glucosidase II with castanospermine | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | | 登録日 | 2016-02-25 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7K0A
 | | Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA | | 分子名称: | 1,2-ETHANEDIOL, COENZYME A, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Peat, T.S, Caputo, A.T, Newman, J, Adams, T.E. | | 登録日 | 2020-09-03 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
Sci Rep, 11, 2021
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6VHI
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8VW6
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7SWS
 | | Crystal structure of the chromoprotein amilCP | | 分子名称: | BROMIDE ION, CHLORIDE ION, Chromoprotein amilCP | | 著者 | Caputo, A.T, Newman, J, Scott, C, Ahmed, H. | | 登録日 | 2021-11-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | | 主引用文献 | Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.
Acta Crystallogr D Struct Biol, 78, 2022
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7SWT
 | | Crystal structure of the chromoprotein eforRED | | 分子名称: | Chromoprotein eforRED | | 著者 | Caputo, A.T, Newman, J, Scott, C, Ahmed, H. | | 登録日 | 2021-11-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.
Acta Crystallogr D Struct Biol, 78, 2022
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7SWR
 | | Crystal structure of the chromoprotein gfasPurple | | 分子名称: | CHLORIDE ION, Chromoprotein gfasPurple | | 著者 | Caputo, A.T, Newman, J, Peat, T.S, Scott, C, Ahmed, H. | | 登録日 | 2021-11-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.388 Å) | | 主引用文献 | Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.
Acta Crystallogr D Struct Biol, 78, 2022
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7SWU
 | | Crystal structure of the chromoprotein spisPINK | | 分子名称: | Chromoprotein spisPINK | | 著者 | Caputo, A.T, Newman, J, Scott, C, Ahmed, H. | | 登録日 | 2021-11-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.444 Å) | | 主引用文献 | Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.
Acta Crystallogr D Struct Biol, 78, 2022
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8CRU
 | | PETase Ancestral Sequence Reconstruction 008 | | 分子名称: | CITRIC ACID, Poly(ethylene terephthalate) hydrolase | | 著者 | Joho, Y, Royan, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | 登録日 | 2022-05-11 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity.
Biochemistry, 62, 2023
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5MZO
 | | UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (open conformation) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | | 登録日 | 2017-02-01 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NV4
 | | UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum double mutant D611C:G1050C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | | 登録日 | 2017-05-03 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8VE9
 | | IsPETase - ACCCETN mutant - CombiPETase | | 分子名称: | CHLORIDE ION, GLYCEROL, Poly(ethylene terephthalate) hydrolase | | 著者 | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEM
 | | IsPETase - ACCE mutant | | 分子名称: | Poly(ethylene terephthalate) hydrolase, SULFATE ION | | 著者 | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | 登録日 | 2023-12-19 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.711 Å) | | 主引用文献 | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEK
 | | IsPETase - ACC mutant | | 分子名称: | GLYCEROL, Poly(ethylene terephthalate) hydrolase, SULFATE ION | | 著者 | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | 登録日 | 2023-12-19 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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8VEL
 | | IsPETase - ACCCC mutant | | 分子名称: | Poly(ethylene terephthalate) hydrolase, SULFATE ION | | 著者 | Joho, Y, Royan, S, Newton, S, Caputo, A.T, Ardevol Grau, A, Jackson, C. | | 登録日 | 2023-12-19 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.624 Å) | | 主引用文献 | Enhancing PET Degrading Enzymes: A Combinatory Approach.
Chembiochem, 25, 2024
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5MU1
 | | UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum soaked with K2PtI6 | | 分子名称: | CALCIUM ION, IODIDE ION, PLATINUM (II) ION, ... | | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | | 登録日 | 2017-01-11 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MHF
 | | Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin. | | 分子名称: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mannosyl-oligosaccharide glucosidase, ... | | 著者 | Hill, J.C, Caputo, A.T, Roversi, P, Zitzmann, N. | | 登録日 | 2016-11-24 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Targeting Endoplasmic Reticulum alpha-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections.
J.Med.Chem., 2020
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