5IED

Murine endoplasmic reticulum alpha-glucosidase II with castanospermine

Summary for 5IED

Entry DOI	10.2210/pdb5ied/pdb
Related	5F0E 5H9O 5HJO 5HJR 5IEE 5IEF 5IEG
Descriptor	Neutral alpha-glucosidase AB, Glucosidase 2 subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	enzyme glycosyl hydrolase gh31 quality control exoglycosidase, hydrolase
Biological source	Mus musculus (Mouse) More
Cellular location	Endoplasmic reticulum : Q8BHN3 O08795
Total number of polymer chains	2
Total formula weight	119250.71
Authors	Caputo, A.T.,Roversi, P.,Alonzi, D.S.,Kiappes, J.L.,Zitzmann, N. (deposition date: 2016-02-25, release date: 2016-07-27, Last modification date: 2024-01-10)
Primary citation	Caputo, A.T.,Alonzi, D.S.,Marti, L.,Reca, I.B.,Kiappes, J.L.,Struwe, W.B.,Cross, A.,Basu, S.,Lowe, E.D.,Darlot, B.,Santino, A.,Roversi, P.,Zitzmann, N. Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proc.Natl.Acad.Sci.USA, 113:E4630-E4638, 2016 Cited by PubMed: 27462106 DOI: 10.1073/pnas.1604463113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation