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4WOL
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BU of 4wol by Molmil
Crystal Structure of the DAP12 transmembrane domain in lipidic cubic phase
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, TYRO protein tyrosine kinase-binding protein
著者Call, M.J, Call, M.E, Knoblich, K.
登録日2014-10-16
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly.
Cell Rep, 11, 2015
4WO1
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BU of 4wo1 by Molmil
Crystal structure of the DAP12 transmembrane domain in lipid cubic phase
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, TYRO protein tyrosine kinase-binding protein
著者Call, M.J, Call, M.E, Knoblich, K.
登録日2014-10-15
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly.
Cell Rep, 11, 2015
5EH6
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BU of 5eh6 by Molmil
Crystal Structure of the Glycophorin A Transmembrane Monomer in Lipidic Cubic Phase
分子名称: Glycophorin-A
著者Call, M.J, Call, M.E, Trenker, R.
登録日2015-10-28
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.918 Å)
主引用文献Crystal Structure of the Glycophorin A Transmembrane Dimer in Lipidic Cubic Phase.
J.Am.Chem.Soc., 137, 2015
5EH4
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BU of 5eh4 by Molmil
Crystal Structure of the Glycophorin A Transmembrane Dimer in Lipidic Cubic Phase
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glycophorin-A
著者Call, M.J, Call, M.E, Trenker, R.
登録日2015-10-28
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structure of the Glycophorin A Transmembrane Dimer in Lipidic Cubic Phase.
J.Am.Chem.Soc., 137, 2015
6WA0
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BU of 6wa0 by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: De novo designed receptor transmembrane domain proMP C3.1
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.484 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Y
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BU of 6w9y by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain proMP 1.2
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
6W9Z
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BU of 6w9z by Molmil
De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain ProMP C2.1
著者Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R.
登録日2020-03-24
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release
To Be Published
8VEC
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BU of 8vec by Molmil
Deep Mutational Scanning of SARS-CoV-2 PLpro
分子名称: Papain-like protease nsp3, ZINC ION
著者Wu, X, Nguyen, J.V, Call, M.E, Call, M.J.
登録日2023-12-18
公開日2024-03-20
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape.
Nat Commun, 15, 2024
4JO8
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BU of 4jo8 by Molmil
Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor 8, M157
著者Berry, R, Ng, N, Saunders, P.M, Vivian, J.P, Lin, J, Deuss, F.A, Corbett, A.J, Forbes, C.A, Widjaja, J.M, Sullivan, L.C, McAlister, A.D, Perugini, M.A, Call, M.J, Scalzo, A.A, Degli-Esposti, M.A, Coudert, J.D, Beddoe, T, Brooks, A.G, Rossjohn, J.
登録日2013-03-18
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Targeting of a natural killer cell receptor family by a viral immunoevasin
Nat.Immunol., 14, 2013
2MIM
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BU of 2mim by Molmil
NMR structure of the chicken CD3 epsilon delta/gamma heterodimer
分子名称: CD3 epsilon protein,CD3 glycoprotein
著者Headey, S, Berry, R, Rossjohn, J.
登録日2013-12-15
公開日2014-02-12
最終更新日2019-01-23
実験手法SOLUTION NMR
主引用文献Structure of the chicken CD3 epsilon delta / gamma heterodimer and its assembly with the alpha beta T cell receptor
J.Biol.Chem., 289, 2014
5W53
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BU of 5w53 by Molmil
Crystal structure of the erythrocyte-binding domain from Plasmodium vivax reticulocyte-binding protein 2b (PvRBP2b)
分子名称: POTASSIUM ION, Reticulocyte binding protein 2, putative, ...
著者Gruszczyk, J, Tham, W.H.
登録日2017-06-13
公開日2017-11-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax.
Science, 359, 2018
7TZJ
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BU of 7tzj by Molmil
SARS CoV-2 PLpro in complex with inhibitor 3k
分子名称: DIMETHYL SULFOXIDE, N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Papain-like protease, ...
著者Calleja, D.J, Klemm, T, Lechtenberg, B.C, Kuchel, N.W, Lessene, G, Komander, D.
登録日2022-02-15
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors.
Front Chem, 10, 2022
4GBX
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BU of 4gbx by Molmil
Crystal structure of an immune complex at pH 6.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-07-28
公開日2013-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
4FQX
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BU of 4fqx by Molmil
Crystal structure of HLA-DM bound to HLA-DR1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ...
著者Sethi, D.K, Pos, W, Wucherpfennig, K.W.
登録日2012-06-25
公開日2013-01-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
6MQV
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BU of 6mqv by Molmil
Structure of HEWL from LCP injector using synchrotron radiation
分子名称: Lysozyme C, SODIUM ION
著者Caradoc-Davies, T.T, Aishima, J, Berntsen, P, Hadian-Jazi, M.
登録日2018-10-10
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The serial millisecond crystallography instrument at the Australian Synchrotron incorporating the "Lipidico" injector.
Rev Sci Instrum, 90, 2019
4I5B
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BU of 4i5b by Molmil
Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Schulze, M.-S.E.D.
登録日2012-11-28
公開日2013-12-04
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Disruption of hydrogen bonds between major histocompatibility complex class II and the peptide N-terminus is not sufficient to form a human leukocyte antigen-DM receptive state of major histocompatibility complex class II.
Plos One, 8, 2013
5VWV
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BU of 5vwv by Molmil
Bak core latch dimer in complex with Bim-BH3 - Cubic
分子名称: 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ...
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VX2
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BU of 5vx2 by Molmil
Mcl-1 in complex with Bim-h3Pc-RT
分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera
著者Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VX0
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BU of 5vx0 by Molmil
Bak in complex with Bim-h3Glg
分子名称: 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ...
著者Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VWW
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BU of 5vww by Molmil
Bak core latch dimer in complex with Bim-RT - Tetragonal
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BROMIDE ION, Bcl-2 homologous antagonist/killer, ...
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VX1
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BU of 5vx1 by Molmil
Bak L100A
分子名称: Bcl-2 homologous antagonist/killer
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.224 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VWY
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BU of 5vwy by Molmil
Bak core latch dimer in complex with Bim-h3Pc-RT
分子名称: Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, PHOSPHATE ION
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.555 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VX3
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Bcl-xL in complex with Bim-h3Pc-RT
分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein 1, Bcl-2-like protein 11
著者Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VWZ
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Bak in complex with Bim-h3Pc
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ...
著者Brouwer, J.M, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.622 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017
5VWX
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BU of 5vwx by Molmil
Bak core latch dimer in complex with Bim-h0-h3Glt
分子名称: 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11
著者Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E.
登録日2017-05-23
公開日2017-11-15
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.489 Å)
主引用文献Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
Mol. Cell, 68, 2017

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