4WOL
| Crystal Structure of the DAP12 transmembrane domain in lipidic cubic phase | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, TYRO protein tyrosine kinase-binding protein | 著者 | Call, M.J, Call, M.E, Knoblich, K. | 登録日 | 2014-10-16 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly. Cell Rep, 11, 2015
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4WO1
| Crystal structure of the DAP12 transmembrane domain in lipid cubic phase | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, TYRO protein tyrosine kinase-binding protein | 著者 | Call, M.J, Call, M.E, Knoblich, K. | 登録日 | 2014-10-15 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly. Cell Rep, 11, 2015
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5EH6
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5EH4
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6WA0
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6W9Y
| De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain proMP 1.2 | 著者 | Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release To Be Published
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6W9Z
| De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, De novo designed receptor transmembrane domain ProMP C2.1 | 著者 | Call, M.J, Call, M.E, Chandler, N.J, Nguyen, J.V, Trenker, R. | 登録日 | 2020-03-24 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | De novo designed receptor transmembrane domains enhance CAR-T cytotoxicity and attenuate cytokine release To Be Published
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8VEC
| Deep Mutational Scanning of SARS-CoV-2 PLpro | 分子名称: | Papain-like protease nsp3, ZINC ION | 著者 | Wu, X, Nguyen, J.V, Call, M.E, Call, M.J. | 登録日 | 2023-12-18 | 公開日 | 2024-03-20 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape. Nat Commun, 15, 2024
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4JO8
| Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor 8, M157 | 著者 | Berry, R, Ng, N, Saunders, P.M, Vivian, J.P, Lin, J, Deuss, F.A, Corbett, A.J, Forbes, C.A, Widjaja, J.M, Sullivan, L.C, McAlister, A.D, Perugini, M.A, Call, M.J, Scalzo, A.A, Degli-Esposti, M.A, Coudert, J.D, Beddoe, T, Brooks, A.G, Rossjohn, J. | 登録日 | 2013-03-18 | 公開日 | 2013-05-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Targeting of a natural killer cell receptor family by a viral immunoevasin Nat.Immunol., 14, 2013
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2MIM
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5W53
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7TZJ
| SARS CoV-2 PLpro in complex with inhibitor 3k | 分子名称: | DIMETHYL SULFOXIDE, N-[(3-fluorophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Papain-like protease, ... | 著者 | Calleja, D.J, Klemm, T, Lechtenberg, B.C, Kuchel, N.W, Lessene, G, Komander, D. | 登録日 | 2022-02-15 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors. Front Chem, 10, 2022
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4GBX
| Crystal structure of an immune complex at pH 6.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... | 著者 | Sethi, D.K, Pos, W, Wucherpfennig, K.W. | 登録日 | 2012-07-28 | 公開日 | 2013-01-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection. Cell(Cambridge,Mass.), 151, 2012
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4FQX
| Crystal structure of HLA-DM bound to HLA-DR1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... | 著者 | Sethi, D.K, Pos, W, Wucherpfennig, K.W. | 登録日 | 2012-06-25 | 公開日 | 2013-01-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection. Cell(Cambridge,Mass.), 151, 2012
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6MQV
| Structure of HEWL from LCP injector using synchrotron radiation | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Caradoc-Davies, T.T, Aishima, J, Berntsen, P, Hadian-Jazi, M. | 登録日 | 2018-10-10 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The serial millisecond crystallography instrument at the Australian Synchrotron incorporating the "Lipidico" injector. Rev Sci Instrum, 90, 2019
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4I5B
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5VWV
| Bak core latch dimer in complex with Bim-BH3 - Cubic | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX2
| Mcl-1 in complex with Bim-h3Pc-RT | 分子名称: | 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera | 著者 | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX0
| Bak in complex with Bim-h3Glg | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11, ... | 著者 | Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWW
| Bak core latch dimer in complex with Bim-RT - Tetragonal | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BROMIDE ION, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VX1
| Bak L100A | 分子名称: | Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.224 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWY
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5VX3
| Bcl-xL in complex with Bim-h3Pc-RT | 分子名称: | 1,2-ETHANEDIOL, Bcl-2-like protein 1, Bcl-2-like protein 11 | 著者 | Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWZ
| Bak in complex with Bim-h3Pc | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ... | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (1.622 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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5VWX
| Bak core latch dimer in complex with Bim-h0-h3Glt | 分子名称: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 11 | 著者 | Brouwer, J.M, Lan, P, Lessene, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2017-05-23 | 公開日 | 2017-11-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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