2FUH
| Solution Structure of the UbcH5c/Ub Non-covalent Complex | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 | 著者 | Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. | 登録日 | 2006-01-26 | 公開日 | 2006-03-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination. Mol.Cell, 21, 2006
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1JM7
| Solution structure of the BRCA1/BARD1 RING-domain heterodimer | 分子名称: | BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION | 著者 | Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E. | 登録日 | 2001-07-17 | 公開日 | 2001-10-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat.Struct.Biol., 8, 2001
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2LPB
| Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 | 分子名称: | General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15 | 著者 | Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S. | 登録日 | 2012-02-07 | 公開日 | 2012-02-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. Mol.Cell, 44, 2011
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2K31
| Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5 | 分子名称: | GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific | 著者 | Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E. | 登録日 | 2008-04-16 | 公開日 | 2008-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change. J.Biol.Chem., 283, 2008
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4BVU
| Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate | 分子名称: | PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3 | 著者 | Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S. | 登録日 | 2013-06-28 | 公開日 | 2014-01-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis. Embo J., 33, 2014
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2MT6
| Solution structure of the human ubiquitin conjugating enzyme Ube2w | 分子名称: | Ubiquitin-conjugating enzyme E2 W | 著者 | Vittal, V, Shi, L, Wenzel, D.M, Brzovic, P.S, Klevit, R.E. | 登録日 | 2014-08-14 | 公開日 | 2014-11-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Intrinsic disorder drives N-terminal ubiquitination by Ube2w. Nat.Chem.Biol., 11, 2015
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8ST7
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8ST9
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8ST8
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3DEU
| Crystal structure of transcription regulatory protein slyA from Salmonella typhimurium in complex with salicylate ligands | 分子名称: | 2-HYDROXYBENZOIC ACID, Transcriptional regulator slyA | 著者 | Le Trong, I, Brzovic, P.S, Fang, F.C, Libby, S.J, Stenkamp, R.E. | 登録日 | 2008-06-10 | 公開日 | 2008-06-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Evolution of SlyA/RovA Transcription Factors from Repressors to Countersilencers in Enterobacteriaceae . Mbio, 10, 2019
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3C5R
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6P5H
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6P5B
| Crystal Structure of MavC in Complex with Ub-UbE2N | 分子名称: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | 著者 | Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. | 登録日 | 2019-05-30 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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4DDI
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4DDG
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2KR4
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7JZV
| Cryo-EM structure of the BRCA1-UbcH5c/BARD1 E3-E2 module bound to a nucleosome | 分子名称: | BRCA1,Ubiquitin-conjugating enzyme E2 D3, BRCA1-associated RING domain protein 1, Histone H2A type 2-A, ... | 著者 | Witus, S.R, Burrell, A.L, Hansen, J.M, Farrell, D.P, Dimaio, F, Kollman, J.M, Klevit, R.E. | 登録日 | 2020-09-02 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1. Nat.Struct.Mol.Biol., 28, 2021
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6ULH
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6UMS
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6UMP
| Crystal structure of MavC in complex with substrate mimic in P65 space group | 分子名称: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | 著者 | Puvar, K, Iyer, S, Luo, Z.Q, Das, C. | 登録日 | 2019-10-10 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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6B7M
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6B7O
| Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin | 分子名称: | Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Mao, Y, Akturk, A, Wasilko, J. | 登録日 | 2017-10-04 | 公開日 | 2018-04-18 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector. Nature, 557, 2018
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6B7P
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6B7Q
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