5D1B
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![BU of 5d1b by Molmil](/molmil-images/mine/5d1b) | Crystal structure of G117E HDAC8 in complex with TSA | 分子名称: | Histone deacetylase 8, POTASSIUM ION, TRICHOSTATIN A, ... | 著者 | Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2015-08-04 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
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5D1D
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![BU of 5d1d by Molmil](/molmil-images/mine/5d1d) | Crystal structure of P91L-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, POTASSIUM ION, ... | 著者 | Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2015-08-04 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | 主引用文献 | Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
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5D1C
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![BU of 5d1c by Molmil](/molmil-images/mine/5d1c) | Crystal structure of D233G-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | GLYCEROL, HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, ... | 著者 | Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2015-08-04 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.422 Å) | 主引用文献 | Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
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5F6H
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![BU of 5f6h by Molmil](/molmil-images/mine/5f6h) | |
5F6J
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![BU of 5f6j by Molmil](/molmil-images/mine/5f6j) | |
5F6I
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![BU of 5f6i by Molmil](/molmil-images/mine/5f6i) | |
4QA5
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![BU of 4qa5 by Molmil](/molmil-images/mine/4qa5) | Crystal structure of A188T/Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA6
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![BU of 4qa6 by Molmil](/molmil-images/mine/4qa6) | Crystal structure of I243N/Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA2
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![BU of 4qa2 by Molmil](/molmil-images/mine/4qa2) | Crystal structure of I243N HDAC8 in complex with SAHA | 分子名称: | GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.377 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA1
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![BU of 4qa1 by Molmil](/molmil-images/mine/4qa1) | Crystal structure of A188T HDAC8 in complex with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA3
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![BU of 4qa3 by Molmil](/molmil-images/mine/4qa3) | Crystal structure of T311M HDAC8 in complex with Trichostatin A (TSA) | 分子名称: | GLYCEROL, Histone deacetylase 8, POTASSIUM ION, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.876 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA7
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![BU of 4qa7 by Molmil](/molmil-images/mine/4qa7) | Crystal structure of H334R/Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA4
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![BU of 4qa4 by Molmil](/molmil-images/mine/4qa4) | Crystal structure of H334R HDAC8 in complex with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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4QA0
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![BU of 4qa0 by Molmil](/molmil-images/mine/4qa0) | Crystal structure of C153F HDAC8 in complex with SAHA | 分子名称: | GLYCEROL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... | 著者 | Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. | 登録日 | 2014-05-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.242 Å) | 主引用文献 | Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
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5KG9
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![BU of 5kg9 by Molmil](/molmil-images/mine/5kg9) | |
5DC7
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![BU of 5dc7 by Molmil](/molmil-images/mine/5dc7) | Crystal structure of D176A-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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5DC5
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![BU of 5dc5 by Molmil](/molmil-images/mine/5dc5) | Crystal structure of D176N HDAC8 in complex with M344 | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, POTASSIUM ION, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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5DC6
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![BU of 5dc6 by Molmil](/molmil-images/mine/5dc6) | Crystal structure of D176N-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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5DC8
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![BU of 5dc8 by Molmil](/molmil-images/mine/5dc8) | Crystal structure of H142A-Y306F HDAC8 in complex with a tetrapeptide substrate | 分子名称: | Fluor-de-Lys tetrapeptide assay substrate, GLYCEROL, Histone deacetylase 8, ... | 著者 | Decroos, C, Lee, M.S, Christianson, D.W. | 登録日 | 2015-08-23 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | General Base-General Acid Catalysis in Human Histone Deacetylase 8. Biochemistry, 55, 2016
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