6MYY
 
 | | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | | 登録日 | 2018-11-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
|
|
6AVQ
 | | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha-V beta-3 Integrin via Steric Hindrance | | 分子名称: | Integrin alpha-V, Integrin beta-3, LM609 Fab heavy chain, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
|
|
6AVR
 | | Human alpha-V beta-3 Integrin (intermediate conformation) in complex with the therapeutic antibody LM609 | | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
|
|
6AVU
 | | Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609 | | 分子名称: | Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ... | | 著者 | Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D. | | 登録日 | 2017-09-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (35 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
|
|
6MZJ
 | | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
|
|
5OPY
 | | Crystal structure of anti-alphaVbeta3 integrin Fab LM609 | | 分子名称: | Heavy chain of LM609 Fab (antigen-binding fragment), Light chain of LM609 Fab (antigen-binding fragment) | | 著者 | Backovic, M, Veesler, D, Borst, A.J, James, Z.M, Zagotta, W, Ginsberg, M, Rey, F.A, DiMaio, F. | | 登録日 | 2017-08-10 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
|
|
8SK7
 | | Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... | | 著者 | Borst, A.J, Bennett, N.R. | | 登録日 | 2023-04-18 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | De novo design of protein structure and function with RFdiffusion.
Nature, 620, 2023
|
|
8F54
 | |
8F4X
 | |
8F53
 | |
5V4S
 | | CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel | | 分子名称: | Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein | | 著者 | James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D. | | 登録日 | 2017-03-10 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
8V3B
 | |
8FWD
 | |
8GA9
 | |
8G8I
 | |
8GAQ
 | |
8GAA
 | |
8TL7
 | |
8CWY
 | |
8E55
 | |
6MFT
 | | Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Weidle, C, Pancera, M, Stamatatos, L, Gray, M. | | 登録日 | 2018-09-12 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.315 Å) | | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
|
|
6P8M
 | |
8V2D
 | |
6P8N
 | |
8SZZ
 | |
