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1BGW
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BU of 1bgw by Molmil
TOPOISOMERASE RESIDUES 410-1202,
分子名称: TOPOISOMERASE
著者Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C.
登録日1996-02-20
公開日1996-07-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and mechanism of DNA topoisomerase II.
Nature, 379, 1996
6DUQ
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BU of 6duq by Molmil
Structure of a Rho-NusG KOW domain complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Berger, J.M, Lawson, M.R.
登録日2018-06-21
公開日2018-09-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.
Mol. Cell, 71, 2018
3C4O
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BU of 3c4o by Molmil
Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex
分子名称: Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION
著者Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M.
登録日2008-01-30
公開日2008-05-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
3KDE
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BU of 3kde by Molmil
Crystal structure of the THAP domain from D. melanogaster P-element transposase in complex with its natural DNA binding site
分子名称: 5'-D(*(BRU)P*CP*CP*AP*CP*TP*TP*AP*AP*C)-3', 5'-D(*GP*TP*TP*AP*AP*GP*(BRU)P*GP*GP*A)-3', Transposable element P transposase, ...
著者Sabogal, A, Lyubimov, A.Y, Berger, J.M, Rio, D.C.
登録日2009-10-22
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves.
Nat.Struct.Mol.Biol., 17, 2010
4MN4
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BU of 4mn4 by Molmil
Structural Basis for the MukB-topoisomerase IV Interaction
分子名称: Chromosome partition protein MukB, DNA topoisomerase 4 subunit A
著者Vos, S.M, Stewart, N.K, Oakley, M.G, Berger, J.M.
登録日2013-09-09
公開日2013-10-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo.
Embo J., 32, 2013
5JJK
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BU of 5jjk by Molmil
Rho transcription termination factor bound to rA7 and 6 ADP-BeF3 molecules
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Thomsen, N.D, Lawson, M.R, Witkowsky, L.B, Qu, S, Berger, J.M.
登録日2016-04-24
公開日2016-11-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
3B39
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BU of 3b39 by Molmil
Structure of the DnaG primase catalytic domain bound to ssDNA
分子名称: DNA (5'-D(*DCP*DAP*DAP*DAP*DGP*DCP*DCP*DAP*DAP*DAP*DAP*DGP*DGP*DAP*DC)-3'), DNA primase
著者Corn, J.E, Pelton, J.G, Berger, J.M.
登録日2007-10-19
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Identification of a DNA primase template tracking site redefines the geometry of primer synthesis.
Nat.Struct.Mol.Biol., 15, 2008
6U0W
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BU of 6u0w by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS K133M at cryogenic temperature
分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
著者Jeliazkov, J.R, Robinson, A.C, Berger, J.M, Garcia-Moreno E, B, Gray, J.G.
登録日2019-08-15
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Toward the computational design of protein crystals with improved resolution.
Acta Crystallogr D Struct Biol, 75, 2019
6U0X
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BU of 6u0x by Molmil
Crystal structure of Staphylococcal nuclease variant Delta+PHS Q123D at cryogenic temperature
分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
著者Jeliazkov, J.R, Robinson, A.C, Berger, J.M, Garcia-Moreno E, B, Gray, J.G.
登録日2019-08-15
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Toward the computational design of protein crystals with improved resolution.
Acta Crystallogr D Struct Biol, 75, 2019
2Q2E
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BU of 2q2e by Molmil
Crystal structure of the topoisomerase VI holoenzyme from Methanosarcina mazei
分子名称: Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit A
著者Corbett, K.D, Benedetti, P, Berger, J.M.
登録日2007-05-28
公開日2007-07-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Holoenzyme assembly and ATP-mediated conformational dynamics of topoisomerase VI
Nat.Struct.Mol.Biol., 14, 2007
2A11
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BU of 2a11 by Molmil
Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis
分子名称: CALCIUM ION, Ribonuclease III
著者Akey, D.L, Berger, J.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-06-17
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
Protein Sci., 14, 2005
1QZR
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BU of 1qzr by Molmil
CRYSTAL STRUCTURE OF THE ATPASE REGION OF SACCHAROMYCES CEREVISIAE TOPOISOMERASE II BOUND TO ICRF-187 (DEXRAZOXANE)
分子名称: (S)-4,4'-(1-METHYL-1,2-ETHANEDIYL)BIS-2,6-PIPERAZINEDIONE, DNA topoisomerase II, MAGNESIUM ION, ...
著者Classen, S, Olland, S, Berger, J.M.
登録日2003-09-17
公開日2003-09-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
Proc.Natl.Acad.Sci.USA, 100, 2003
437D
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BU of 437d by Molmil
CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING
分子名称: MAGNESIUM ION, RNA PSEUDOKNOT, SODIUM ION
著者Su, L, Chen, L, Egli, M, Berger, J.M, Rich, A.
登録日1998-11-24
公開日1998-12-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
7UGW
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BU of 7ugw by Molmil
M. tuberculosis DNA gyrase cleavage core bound to DNA and evybactin
分子名称: DNA (46-MER), DNA gyrase subunit A, DNA gyrase subunit B, ...
著者Hauk, G, Imai, Y, Lewis, K, Berger, J.M.
登録日2022-03-25
公開日2022-08-17
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Evybactin is a DNA gyrase inhibitor that selectively kills Mycobacterium tuberculosis.
Nat.Chem.Biol., 18, 2022
1BJT
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BU of 1bjt by Molmil
TOPOISOMERASE II RESIDUES 409-1201
分子名称: TOPOISOMERASE II
著者Fass, D, Bogden, C.E, Berger, J.M.
登録日1998-06-29
公開日1999-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands.
Nat.Struct.Biol., 6, 1999
4NMN
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BU of 4nmn by Molmil
Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ...
著者Lyubimov, A.Y, Strycharska, M.S, Erzberger, J.P, Berger, J.M.
登録日2013-11-15
公開日2014-01-29
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
Mol.Cell, 52, 2013
1L8Q
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BU of 1l8q by Molmil
CRYSTAL STRUCTURE OF DNA REPLICATION INITIATION FACTOR
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosomal replication initiator protein dnaA, MAGNESIUM ION
著者Erzberger, J.P, Pirruccello, M.M, Berger, J.M.
登録日2002-03-21
公開日2002-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation
Embo J., 21, 2002
4WMG
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BU of 4wmg by Molmil
Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A)
分子名称: Lysozyme C
著者Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M.
登録日2014-10-08
公開日2015-04-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
Acta Crystallogr.,Sect.D, 71, 2015
4XGC
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BU of 4xgc by Molmil
Crystal structure of the eukaryotic origin recognition complex
分子名称: CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Bleichert, F, Botchan, M.R, Berger, J.M.
登録日2014-12-30
公開日2015-04-01
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the eukaryotic origin recognition complex.
Nature, 519, 2015
4TMA
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BU of 4tma by Molmil
Crystal structure of gyrase bound to its inhibitor YacG
分子名称: DNA gyrase inhibitor YacG, DNA gyrase subunit A, DNA gyrase subunit B, ...
著者Vos, S.M, Lyubimov, A.Y, Hershey, D.M, Schoeffler, A.J, Berger, J.M.
登録日2014-05-31
公開日2014-07-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Direct control of type IIA topoisomerase activity by a chromosomally encoded regulatory protein.
Genes Dev., 28, 2014
4TXY
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BU of 4txy by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.0001 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
6QEL
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BU of 6qel by Molmil
E. coli DnaBC apo complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication protein dnaC, MAGNESIUM ION, ...
著者Arias-Palomo, E, Puri, N, O'Shea Murray, V.L, Yan, Q, Berger, J.M.
登録日2019-01-08
公開日2019-03-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
Mol.Cell, 74, 2019
4TY0
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BU of 4ty0 by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG
分子名称: ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ...
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
6QEM
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BU of 6qem by Molmil
E. coli DnaBC complex bound to ssDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication protein DnaC, MAGNESIUM ION, ...
著者Arias-Palomo, E, Puri, N, O'Shea Murray, V.L, Yan, Q, Berger, J.M.
登録日2019-01-08
公開日2019-03-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
Mol.Cell, 74, 2019
4TXZ
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BU of 4txz by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014

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