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6XCN
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BU of 6xcn by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-06-08
公開日2020-07-01
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCM
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BU of 6xcm by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-06-08
公開日2020-07-01
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6OIX
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BU of 6oix by Molmil
Structure of Escherichia coli dGTPase bound to GTP
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
5C4X
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BU of 5c4x by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4J
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BU of 5c4j by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-18
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4A
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BU of 5c4a by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C3E
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BU of 5c3e by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C44
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BU of 5c44 by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
登録日2015-06-17
公開日2015-08-26
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
7K8S
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BU of 7k8s by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
著者Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
6CHB
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BU of 6chb by Molmil
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and IOMA
分子名称: BG18 Heavy Chain, BG18 Light Chain, Envelope glycoprotein gp120, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-02-22
公開日2018-05-02
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (6.801 Å)
主引用文献Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH9
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BU of 6ch9 by Molmil
Crystal structure of a natively-glycosylated B41 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-02-22
公開日2018-05-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.85 Å)
主引用文献Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH7
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BU of 6ch7 by Molmil
XFEL crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-02-22
公開日2018-05-02
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH8
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BU of 6ch8 by Molmil
Crystal structure of a natively-glycosylated BG505 SOSIP.664 HIV-1 Envelope Trimer in complex with the broadly-neutralizing antibodies BG18 and 35O22
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy Chain, 35O22 Light Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2018-02-22
公開日2018-05-02
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6OIW
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BU of 6oiw by Molmil
Structure of Escherichia coli dGTPase bound to dGTP-1-thiol
分子名称: 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, ...
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIY
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BU of 6oiy by Molmil
Structure of Escherichia coli bound to dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIV
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BU of 6oiv by Molmil
XFEL structure of Escherichia coli dGTPase
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION, SULFATE ION
著者Barnes, C.O, Wu, Y, Calero, G.
登録日2019-04-09
公開日2019-06-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
7UCE
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BU of 7uce by Molmil
Structure of the anti-HIV-1 neutralizing antibody BG24 Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG24 Fab heavy chain, BG24 Fab light chain
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCF
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BU of 7ucf by Molmil
Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCG
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BU of 7ucg by Molmil
Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7K8Z
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BU of 7k8z by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C135
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C135 Fab Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8U
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BU of 7k8u by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C104 Fab Heavy Chain, ...
著者Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K90
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BU of 7k90 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ...
著者Barnes, C.O, Esswein, S.R, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
8E7M
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BU of 8e7m by Molmil
Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04
分子名称: 05B04 Heavy Chain, 05B04 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O.
登録日2022-08-24
公開日2022-09-28
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents
Biorxiv, 2022
7R8N
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BU of 7r8n by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C051 Fab Heavy Chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8L
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BU of 7r8l by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
分子名称: C099 Fab Heavy Chain, C099 Fab Light Chain, CR3022 Fab heavy chain, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2021-06-26
公開日2021-08-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021

 

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