3TCQ
| Crystal Structure of matrix protein VP40 from Ebola virus Sudan | 分子名称: | Matrix protein VP40 | 著者 | Clifton, M.C, Edwards, T.E, Anderson, V, Atkins, K, Raymond, A, Saphire, E.O, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2011-08-09 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus. J Infect Dis, 212 Suppl 2, 2015
|
|
4FN2
| |
3UF8
| |
3UQA
| |
5J5T
| GLK co-crystal structure with aminopyrrolopyrimidine inhibitor | 分子名称: | 5-[2-(piperidin-4-yl)-1,3-thiazol-5-yl]-3-[(pyridin-4-yl)methoxy]pyridin-2-amine, Mitogen-activated protein kinase kinase kinase kinase 3 | 著者 | Silvian, L.F, Marcotte, D. | 登録日 | 2016-04-03 | 公開日 | 2016-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Germinal-center kinase-like kinase co-crystal structure reveals a swapped activation loop and C-terminal extension. Protein Sci., 26, 2017
|
|
5E0I
| |
3UQB
| |
3VAW
| |
4DZ3
| |
4DZ2
| |
5WHK
| Crystal structure of Fab fragment of antibody DX-2507 bound to FcRn-B2M | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, ... | 著者 | Edwards, T.E, Clifton, M.C, Nixon, A.E, Kenniston, J.A. | 登録日 | 2017-07-17 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
|
|
5WHJ
| Crystal structure of Fab fragment of anti-FcRn antibody DX-2507 | 分子名称: | DX-2507 Fab heavy chain, DX-2507 Fab light chain | 著者 | Edwards, T.E, Fairman, J.W, Nixon, A.E, Kenniston, J.A. | 登録日 | 2017-07-17 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody. J. Biol. Chem., 292, 2017
|
|
4G50
| |
4GIV
| |
4GGQ
| |
3V7O
| |
4XUZ
| |
4XUX
| Structure of ampC bound to RPX-7009 at 1.75 A | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Beta-lactamase, ... | 著者 | Clifton, M.C, Abendroth, J. | 登録日 | 2015-01-26 | 公開日 | 2015-04-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of a Cyclic Boronic Acid beta-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. J.Med.Chem., 58, 2015
|
|
7MFC
| |
3S41
| Glucokinase in complex with activator and glucose | 分子名称: | Glucokinase, N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide, SODIUM ION, ... | 著者 | Liu, S. | 登録日 | 2011-05-18 | 公開日 | 2011-09-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus MEDCHEMCOMM, 2, 2011
|
|
5JQ1
| |
5JPV
| |
4L3Q
| |