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2LB0
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BU of 2lb0 by Molmil
Structure of the first WW domain of human Smurf1 in complex with a di-phosphorylated human Smad1 derived peptide
分子名称: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAX
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BU of 2lax by Molmil
Structure of first WW domain of human YAP in complex with a human Smad1 doubly-phosphorilated derived peptide.
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTV
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BU of 2ltv by Molmil
YAP WW2 in complex with a Smad7 derived peptide
分子名称: Smad7 derived peptide, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAY
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BU of 2lay by Molmil
Structure of the first WW domain of human YAP in complex with a phosphorylated human Smad1 derived peptide
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB2
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BU of 2lb2 by Molmil
Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB1
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BU of 2lb1 by Molmil
Structure of the second domain of human Smurf1 in complex with a human Smad1 derived peptide
分子名称: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2016-04-27
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LAJ
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BU of 2laj by Molmil
Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 3
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-16
公開日2011-07-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTY
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BU of 2lty by Molmil
NEDD4L WW2 domain in complex with a Smad7 derived peptide
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Smad7 derived peptide
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LTX
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BU of 2ltx by Molmil
Smurf1 WW2 domain in complex with a Smad7 derived peptide
分子名称: E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LTZ
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BU of 2ltz by Molmil
Smurf2 WW3 domain in complex with a Smad7 derived peptide
分子名称: E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAZ
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BU of 2laz by Molmil
Structure of the first WW domain of human Smurf1 in complex with a mono-phosphorylated human Smad1 derived peptide
分子名称: E3 ubiquitin-protein ligase SMURF1, Mothers against decapentaplegic homolog 1
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LTW
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BU of 2ltw by Molmil
YAP WW1 in complex with a Smad7 derived peptide
分子名称: Smad7 derived peptide, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Xi, Q, Lopes, T, Gao, S, Massague, J.
登録日2012-06-04
公開日2012-11-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-beta Pathways.
Structure, 20, 2012
2LAW
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BU of 2law by Molmil
Structure of the second WW domain from human YAP in complex with a human Smad1 derived peptide
分子名称: Mothers against decapentaplegic homolog 1, Yorkie homolog
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
2LB3
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BU of 2lb3 by Molmil
Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide
分子名称: Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J.
登録日2011-03-22
公開日2011-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Genes Dev., 25, 2011
6Z7O
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BU of 6z7o by Molmil
Crystal structure of Thioredoxin T from Drosophila melanogaster
分子名称: Thioredoxin-T, ZINC ION
著者Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M.
登録日2020-05-31
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins.
Iucrj, 8, 2021
4R9P
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BU of 4r9p by Molmil
An Expansion to the Smad MH2-family: The structure of the N-MH2 expanded domain
分子名称: RE28239p
著者Beich-Frandsen, M, Aragon, E, Llimargas, M, Benach, J, Riera, A, Macias, M.J.
登録日2014-09-06
公開日2015-04-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.592 Å)
主引用文献Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2
Acta Crystallogr.,Sect.D, 71, 2015
2MPT
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BU of 2mpt by Molmil
WW3 domain of Nedd4L in complex with its HECT domain PY motif
分子名称: E3 ubiquitin-protein ligase NEDD4-like
著者Escobedo, A, Macias, M.J, Gomes, T, Aragon, E, Martin-Malpartida, P, Ruiz, L.
登録日2014-06-02
公開日2014-10-22
実験手法SOLUTION NMR
主引用文献Structural Basis of the Activation and Degradation Mechanisms of the E3 Ubiquitin Ligase Nedd4L.
Structure, 22, 2014
6H3R
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BU of 6h3r by Molmil
Crystal structure of Smad2 without exon -MH1 bound to the CAGAC site.
分子名称: DNA (5'-D(P*GP*AP*GP*TP*GP*TP*CP*TP*GP*CP*AP*GP*AP*CP*AP*CP*TP*C)-3'), Mothers against decapentaplegic homolog, ZINC ION
著者Kaczmarska, Z, Marquez, J.A, Macias, M.J.
登録日2018-07-19
公開日2019-09-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-beta signaling
Genes Dev., 2020
6ZMU
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BU of 6zmu by Molmil
Crystal structure of the germline-specific thioredoxin protein Deadhead (Thioredoxin-1) from Drospohila melanogaster, P43212
分子名称: SODIUM ION, SULFATE ION, Thioredoxin-1
著者Baginski, B, Pluta, R, Macias, M.J.
登録日2020-07-03
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins.
Iucrj, 8, 2021
6TBZ
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BU of 6tbz by Molmil
Crystal structure of the MH1 domain of Smad5-Smad3 chimera construct bound to the GGCGC site
分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 5, ZINC ION
著者Pluta, R, Macias, M.J.
登録日2019-11-04
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Comput Struct Biotechnol J, 19, 2021
6TCE
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BU of 6tce by Molmil
Crystal structure of the GGCT site-bound MH1 domain of Smad5 containing a GGGS insertion in the Loop1
分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 5, ZINC ION
著者Pluta, R, Macias, M.J.
登録日2019-11-05
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Comput Struct Biotechnol J, 19, 2021
6Y1Q
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BU of 6y1q by Molmil
Cortistatin analog with improved immunoregulatory activity
分子名称: Analog 5, OCTANOIC ACID (CAPRYLIC ACID)
著者Rol, A.
登録日2020-02-13
公開日2021-01-27
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structure-based design of a Cortistatin analogue with immunomodulatory activity in models of inflammatory bowel disease.
Nat Commun, 12, 2021
6ZMN
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BU of 6zmn by Molmil
Crystal structure of the Smad3-Smad5 MH1 domain chimera bound to the GGCGC site
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), ...
著者Pluta, R, Macias, M.J.
登録日2020-07-03
公開日2020-08-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.333 Å)
主引用文献Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Comput Struct Biotechnol J, 19, 2021
6FQP
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BU of 6fqp by Molmil
Crystal structure of TALE homeobox domain transcription factor TGIF1 with its consensus DNA
分子名称: CALCIUM ION, DNA (5'-D(P*AP*TP*TP*GP*AP*CP*AP*GP*CP*TP*GP*TP*CP*AP*AP*T)-3'), Homeobox protein TGIF1
著者Guca, E, Macias, M.J.
登録日2018-02-14
公開日2018-07-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling.
Nucleic Acids Res., 46, 2018
6FQQ
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BU of 6fqq by Molmil
Crystal structure of TALE homeobox domain transcription factor TGIF1 double alanine mutant bound to its consensus DNA
分子名称: CHLORIDE ION, DNA (5'-D(P*AP*TP*TP*GP*AP*CP*AP*GP*CP*TP*GP*TP*CP*AP*AP*T)-3'), Homeobox protein TGIF1
著者Guca, E, Macias, M.J.
登録日2018-02-14
公開日2018-07-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.25000262 Å)
主引用文献TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling.
Nucleic Acids Res., 46, 2018

 

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