1K23
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![BU of 1k23 by Molmil](/molmil-images/mine/1k23) | Inorganic Pyrophosphatase (Family II) from Bacillus subtilis | 分子名称: | MANGANESE (II) ION, Manganese-dependent inorganic pyrophosphatase | 著者 | Ahn, S, Milner, A.J, Futterer, K, Konopka, M, Ilias, M, Young, T.W, White, S.A. | 登録日 | 2001-09-26 | 公開日 | 2001-10-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The "open" and "closed" structures of the type-C inorganic pyrophosphatases from Bacillus subtilis and Streptococcus gordonii. J.Mol.Biol., 313, 2001
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1K20
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![BU of 1k20 by Molmil](/molmil-images/mine/1k20) | Inorganic Pyrophosphatase (family II) from Streptococcus gordonii at 1.5 A resolution | 分子名称: | GLYCEROL, MANGANESE (II) ION, Manganese-dependent inorganic pyrophosphatase, ... | 著者 | Ahn, S, Milner, A.J, Futterer, K, Konopka, M, Ilias, M, Young, T.W, White, S.A. | 登録日 | 2001-09-26 | 公開日 | 2001-10-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The "open" and "closed" structures of the type-C inorganic pyrophosphatases from Bacillus subtilis and Streptococcus gordonii. J.Mol.Biol., 313, 2001
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5T3M
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2Q9T
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![BU of 2q9t by Molmil](/molmil-images/mine/2q9t) | High-resolution structure of the DING protein from Pseudomonas fluorescens | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DING, ... | 著者 | Moniot, S, Ahn, S, Elias, M, Kim, D, Scott, K, Chabriere, E. | 登録日 | 2007-06-14 | 公開日 | 2008-06-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structure-function relationships in a bacterial DING protein. Febs Lett., 581, 2007
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5X7D
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![BU of 5x7d by Molmil](/molmil-images/mine/5x7d) | Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Liu, X, Ahn, S, Kahsai, A.W, Meng, K.-C, Latorraca, N.R, Pani, B, Venkatakrishnan, A.J, Masoudi, A, Weis, W.I, Dror, R.O, Chen, X, Lefkowitz, R.J, Kobilka, B.K. | 登録日 | 2017-02-25 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Mechanism of intracellular allosteric beta 2AR antagonist revealed by X-ray crystal structure. Nature, 548, 2017
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5JQH
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![BU of 5jqh by Molmil](/molmil-images/mine/5jqh) | Structure of beta2 adrenoceptor bound to carazolol and inactive-state stabilizing nanobody, Nb60 | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, CHOLESTEROL, Endolysin,Beta-2 adrenergic receptor, ... | 著者 | Staus, D.P, Strachan, R.T, Manglik, A, Pani, B, Kahsai, A.W, Kim, T.H, Wingler, L.M, Ahn, S, Chatterjee, A, Masoudi, A, Kruse, A.C, Pardon, E, Steyaert, J, Weis, W.I, Prosser, R.S, Kobilka, B.K, Costa, T, Lefkowitz, R.J. | 登録日 | 2016-05-05 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation. Nature, 535, 2016
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6N48
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![BU of 6n48 by Molmil](/molmil-images/mine/6n48) | Structure of beta2 adrenergic receptor bound to BI167107, Nanobody 6B9, and a positive allosteric modulator | 分子名称: | (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid Antibody Fragment, ... | 著者 | Liu, X, Masoudi, A, Kahsai, A.W, Huang, L.Y, Pani, B, Hirata, K, Ahn, S, Lefkowitz, R.J, Kobilka, B.K. | 登録日 | 2018-11-17 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Mechanism of beta2AR regulation by an intracellular positive allosteric modulator. Science, 364, 2019
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5UP8
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![BU of 5up8 by Molmil](/molmil-images/mine/5up8) | Crystal Structure of the Zn-bound Human Heavy-Chain variant 122H-delta C-star with para-benzenedihydroxamate | 分子名称: | Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ... | 著者 | Bailey, J.B, Zhang, L, Chiong, J.C, Ahn, S, Tezcan, F.A. | 登録日 | 2017-02-01 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.631 Å) | 主引用文献 | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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5CMQ
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![BU of 5cmq by Molmil](/molmil-images/mine/5cmq) | Crystal Structure of Zn-bound Human H-Ferritin variant 122H-delta C-star | 分子名称: | Ferritin heavy chain, ZINC ION | 著者 | Sontz, P.A, Bailey, J.B, Ahn, S, Tezcan, F.A. | 登録日 | 2015-07-17 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.935 Å) | 主引用文献 | A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals. J.Am.Chem.Soc., 137, 2015
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5CMR
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![BU of 5cmr by Molmil](/molmil-images/mine/5cmr) | Crystal Structure of Linker-Mediated Zn-bound Human H-Ferritin variant 122H-delta C-star | 分子名称: | Ferritin heavy chain, N,N'-dihydroxybenzene-1,4-dicarboxamide, SODIUM ION, ... | 著者 | Sontz, P.A, Bailey, J.B, Ahn, S, Tezcan, F.A. | 登録日 | 2015-07-17 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.792 Å) | 主引用文献 | A Metal Organic Framework with Spherical Protein Nodes: Rational Chemical Design of 3D Protein Crystals. J.Am.Chem.Soc., 137, 2015
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5UP9
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![BU of 5up9 by Molmil](/molmil-images/mine/5up9) | Crystal Structure of Zn-bound Human Heavy-Chain ferritin variant 122H-delta C-star with para-xylenedihydroxamate | 分子名称: | 2,2'-(1,4-phenylene)bis(N-hydroxyacetamide), DI(HYDROXYETHYL)ETHER, Ferritin heavy chain, ... | 著者 | Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A. | 登録日 | 2017-02-01 | 公開日 | 2017-09-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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5UP7
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![BU of 5up7 by Molmil](/molmil-images/mine/5up7) | Crystal Structure of the Ni-bound Human Heavy-Chain Ferritin 122H-delta C-star variant | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A. | 登録日 | 2017-02-01 | 公開日 | 2017-06-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
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6MZC
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![BU of 6mzc by Molmil](/molmil-images/mine/6mzc) | Human TFIID BC core | 分子名称: | Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ... | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | 登録日 | 2018-11-05 | 公開日 | 2018-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6MZM
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![BU of 6mzm by Molmil](/molmil-images/mine/6mzm) | Human TFIID bound to promoter DNA and TFIIA | 分子名称: | SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | 登録日 | 2018-11-05 | 公開日 | 2018-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6MZD
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![BU of 6mzd by Molmil](/molmil-images/mine/6mzd) | Human TFIID Lobe A canonical | 分子名称: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | 登録日 | 2018-11-05 | 公開日 | 2018-11-28 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (9.8 Å) | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6MZL
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![BU of 6mzl by Molmil](/molmil-images/mine/6mzl) | Human TFIID canonical state | 分子名称: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | 登録日 | 2018-11-05 | 公開日 | 2018-11-28 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (23 Å) | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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5DLB
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![BU of 5dlb by Molmil](/molmil-images/mine/5dlb) | Crystal structure of chaperone EspG3 of ESX-3 type VII secretion system from Mycobacterium marinum M | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, PLATINUM (II) ION, ... | 著者 | Chan, S, Arbing, M.A, Kim, J, Kahng, S, Sawaya, M.R, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-09-04 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems. J. Mol. Biol., 431, 2019
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5CYU
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![BU of 5cyu by Molmil](/molmil-images/mine/5cyu) | Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system. | 分子名称: | Conserved membrane protein | 著者 | Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-30 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
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3C0T
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![BU of 3c0t by Molmil](/molmil-images/mine/3c0t) | Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18 | 分子名称: | Mediator of RNA polymerase II transcription subunit 18, Mediator of RNA polymerase II transcription subunit 8 | 著者 | Lariviere, L, Seizl, M, van Wageningen, S, Roether, S, van de Pasch, L, Feldmann, H, Straesser, K, Hahn, S, Holstege, C.P, Cramer, P. | 登録日 | 2008-01-21 | 公開日 | 2008-04-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-system correlation identifies a gene regulatory Mediator submodule Genes Dev., 22, 2008
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1JA9
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![BU of 1ja9 by Molmil](/molmil-images/mine/1ja9) | Crystal structure of 1,3,6,8-tetrahydroxynaphthalene reductase in complex with NADPH and pyroquilon | 分子名称: | 1,3,6,8-tetrahydroxynaphthalene reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYROQUILON | 著者 | Liao, D.-I, Thompson, J.E, Fahnestock, S, Valent, B, Jordan, D.B. | 登録日 | 2001-05-30 | 公開日 | 2001-09-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A structural account of substrate and inhibitor specificity differences between two naphthol reductases. Biochemistry, 40, 2001
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6ALY
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![BU of 6aly by Molmil](/molmil-images/mine/6aly) | Solution structure of yeast Med15 ABD2 residues 277-368 | 分子名称: | Mediator of RNA polymerase II transcription subunit 15 | 著者 | Tuttle, L.M, Pacheco, D, Warfield, L, Hahn, S, Klevit, R.E. | 登録日 | 2017-08-08 | 公開日 | 2018-03-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex. Cell Rep, 22, 2018
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1YTB
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![BU of 1ytb by Molmil](/molmil-images/mine/1ytb) | CRYSTAL STRUCTURE OF A YEAST TBP/TATA-BOX COMPLEX | 分子名称: | DNA (29MER), PROTEIN (TATA BINDING PROTEIN (TBP)) | 著者 | Kim, Y, Geiger, J.H, Hahn, S, Sigler, P.B. | 登録日 | 1994-09-28 | 公開日 | 1995-01-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of a yeast TBP/TATA-box complex. Nature, 365, 1993
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2LPB
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![BU of 2lpb by Molmil](/molmil-images/mine/2lpb) | Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 | 分子名称: | General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15 | 著者 | Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S. | 登録日 | 2012-02-07 | 公開日 | 2012-02-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. Mol.Cell, 44, 2011
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2BHH
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![BU of 2bhh by Molmil](/molmil-images/mine/2bhh) | HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE | 分子名称: | (2E,3S)-3-HYDROXY-5'-[(4-HYDROXYPIPERIDIN-1-YL)SULFONYL]-3-METHYL-1,3-DIHYDRO-2,3'-BIINDOL-2'(1'H)-ONE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Schaefer, M, Jautelat, R, Brumby, T, Briem, H, Eisenbrand, G, Schwahn, S, Krueger, M, Luecking, U, Prien, O, Siemeister, G. | 登録日 | 2005-01-11 | 公開日 | 2005-03-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | From the Insoluble Dye Indirubin Towards Highly Active, Soluble Cdk2-Inhibitors Chembiochem, 6, 2005
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2BHE
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![BU of 2bhe by Molmil](/molmil-images/mine/2bhe) | HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 5-BROMO-INDIRUBINE | 分子名称: | (2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Schaefer, M, Jautelat, R, Brumby, T, Briem, H, Eisenbrand, G, Schwahn, S, Krueger, M, Luecking, U, Prien, O, Siemeister, G. | 登録日 | 2005-01-10 | 公開日 | 2005-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | From the Insoluble Dye Indirubin Towards Highly Active, Soluble Cdk2-Inhibitors Chembiochem, 6, 2005
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