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1FQV
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BU of 1fqv by Molmil
Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
分子名称: SKP1, SKP2
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-06
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS2
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BU of 1fs2 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
分子名称: SKP1, SKP2
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-08
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
1FS1
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BU of 1fs1 by Molmil
INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX
分子名称: CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45
著者Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P.
登録日2000-09-08
公開日2000-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
8QYJ
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BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QZ9
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BU of 8qz9 by Molmil
Human 20S proteasome assembly intermediate structure 4
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYM
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BU of 8qym by Molmil
Human 20S proteasome assembly intermediate structure 3
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYN
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BU of 8qyn by Molmil
Human 20S proteasome assembly intermediate structure 5
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYO
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BU of 8qyo by Molmil
Human proteasome 20S core particle
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYL
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BU of 8qyl by Molmil
Human 20S proteasome assembly intermediate structure 2
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYS
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BU of 8qys by Molmil
Human preholo proteasome 20S core particle
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
3IVQ
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BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
分子名称: CiSBC2, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVV
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BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
分子名称: PucSBC1, Speckle-type POZ protein
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-09-01
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
分子名称: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-08-31
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure 9
To be Published
7WUG
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BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
分子名称: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
著者Qiao, S, Cheng, J.D, Schulman, B.A.
登録日2022-02-08
公開日2022-06-08
最終更新日2022-06-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
7OD1
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BU of 7od1 by Molmil
Crystal structure of RBR ubiquitin ligase ARIH2
分子名称: E3 ubiquitin-protein ligase ARIH2, ZINC ION
著者Kostrhon, S.P, Prabu, J.R, Schulman, B.A.
登録日2021-04-28
公開日2021-09-15
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
5JG6
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BU of 5jg6 by Molmil
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
分子名称: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION
著者Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A.
登録日2016-04-19
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0013 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
7QQY
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BU of 7qqy by Molmil
yeast Gid10 bound to Art2 Pro/N-degron
分子名称: CHLORIDE ION, ECM21, Uncharacterized protein YGR066C
著者Chrustowicz, J, Sherpa, D, Schulman, B.A.
登録日2022-01-10
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters.
Embo Rep., 23, 2022
4F52
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BU of 4f52 by Molmil
Structure of a Glomulin-RBX1-CUL1 complex
分子名称: Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ...
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2012-05-11
公開日2012-09-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface.
Mol.Cell, 47, 2012
7ZBZ
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BU of 7zbz by Molmil
CAND1 delhairpin-SCF-SKP2 CAND1 partly engaged SCF partly rocked
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-24
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8B
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BU of 7z8b by Molmil
Structure of CRL7FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation
分子名称: Cullin-7, E3 ubiquitin-protein ligase RBX1, F-box/WD repeat-containing protein 8, ...
著者Hopf, L.V.M, Schulman, B.A.
登録日2022-03-17
公開日2022-08-24
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of CRL7 FBXW8 reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation.
Nat.Struct.Mol.Biol., 29, 2022
7Z8T
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BU of 7z8t by Molmil
CAND1-SCF-SKP2 CAND1 engaged SCF rocked
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-18
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7ZBW
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BU of 7zbw by Molmil
CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-24
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8R
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BU of 7z8r by Molmil
CAND1-CUL1-RBX1
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-18
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Z8V
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BU of 7z8v by Molmil
CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ...
著者Baek, K, Schulman, B.A.
登録日2022-03-18
公開日2023-04-19
最終更新日2023-05-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
7Q4Y
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BU of 7q4y by Molmil
human Gid4 bound to a Gly/N-peptide
分子名称: Glucose-induced degradation protein 4 homolog
著者Sherpa, D, Chrustowicz, J, Prabu, J.R, Schulman, B.A.
登録日2021-11-02
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022

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