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3BXJ
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BU of 3bxj by Molmil
Crystal Structure of the C2-GAP Fragment of synGAP
分子名称: Ras GTPase-activating protein SynGAP
著者Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K.
登録日2008-01-14
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction.
Embo Rep., 9, 2008
3IM2
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BU of 3im2 by Molmil
Structure of the C-terminal Sec63 unit of yeast Brr2, P41212 Form
分子名称: Pre-mRNA-splicing helicase BRR2, TETRAETHYLENE GLYCOL
著者Pena, V, Hrmann, R.L, Wahl, M.C.
登録日2009-08-09
公開日2009-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
To be Published
3IM1
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BU of 3im1 by Molmil
Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form
分子名称: Pre-mRNA-splicing helicase BRR2
著者Pena, V, Hrmann, R.L, Wahl, M.C.
登録日2009-08-09
公開日2009-08-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase
To be Published
2OG4
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BU of 2og4 by Molmil
Structure of an expanded Jab1-MPN-like domain of splicing factor Prp8p from yeast
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Liu, S, Luehrmann, R, Wahl, M.C.
登録日2007-01-05
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.
Mol.Cell, 25, 2007
3E9L
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BU of 3e9l by Molmil
Crystal Structure of Human Prp8, Residues 1755-2016
分子名称: CHLORIDE ION, Pre-mRNA-processing-splicing factor 8, SODIUM ION
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
3E9O
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BU of 3e9o by Molmil
Crystal Structure of Yeast Prp8, Residues 1836-2092
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
3E9P
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BU of 3e9p by Molmil
Crystal Structure of Yeast Prp8, Residues 1827-2092
分子名称: Pre-mRNA-splicing factor 8
著者Pena, V, Rozov, A, Wahl, M.C.
登録日2008-08-22
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and function of an RNase H domain at the heart of the spliceosome.
Embo J., 27, 2008
5HY7
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BU of 5hy7 by Molmil
SF3B10-SF3B130 from Chaetomium thermophilum
分子名称: CALCIUM ION, Putative pre-mRNA splicing protein, YSF3
著者Ponce-Salvatierra, A, Schmitzova, J, Pena, V.
登録日2016-02-01
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Mol.Cell, 64, 2016
7OA3
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BU of 7oa3 by Molmil
Crystal structure of Chili RNA aptamer in complex with DMHBO+ (Iridium hexammine co-crystallized form)
分子名称: Chili RNA Aptamer, DMHBO+, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Mieczkowski, M, Pena, V, Hoebartner, C.
登録日2021-04-19
公開日2021-06-16
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine.
Nat Commun, 12, 2021
7OAX
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BU of 7oax by Molmil
Crystal structure of the Chili RNA aptamer in complex with DMHBO+
分子名称: CHLORIDE ION, Chili RNA Aptamer, DMHBO+, ...
著者Mieczkowski, M, Pena, V, Hoebartner, C.
登録日2021-04-20
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine.
Nat Commun, 12, 2021
7OAW
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BU of 7oaw by Molmil
Crystal structure of the Chili RNA aptamer in complex with DMHBI+
分子名称: CHLORIDE ION, Chili RNA Aptamer, DMHBI+, ...
著者Mieczkowski, M, Pena, V, Hoebartner, C.
登録日2021-04-20
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine.
Nat Commun, 12, 2021
7OAV
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BU of 7oav by Molmil
Crystal structure of Chili RNA aptamer in complex with DMHBO+ (Iridium III hexammine soaking crystal form)
分子名称: CHLORIDE ION, Chili RNA Aptamer, DMHBO+, ...
著者Mieczkowski, M, Pena, V, Hoebartner, C.
登録日2021-04-20
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine.
Nat Commun, 12, 2021
7B92
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BU of 7b92 by Molmil
Structure of a minimal SF3B core in complex with sudemycin D6 (form II)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7B9C
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BU of 7b9c by Molmil
Structure of a minimal SF3B core in complex with spliceostatin A (form I)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7B91
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BU of 7b91 by Molmil
Structure of a minimal SF3B core in complex with pladienolide D (form I)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-12-13
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7QTT
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BU of 7qtt by Molmil
Structural organization of a late activated human spliceosome (Baqr, core region)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Cretu, C, Pena, V.
登録日2022-01-15
公開日2023-05-10
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
7OPI
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BU of 7opi by Molmil
Structure of a minimal SF3B core in complex with the inactive modulator spliceostatin E (form I)
分子名称: PHD finger-like domain-containing protein 5A, Spliceostatin E (form I), Splicing factor 3B subunit 1, ...
著者Cretu, C, Pena, V.
登録日2021-05-31
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7ONB
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BU of 7onb by Molmil
Structure of the U2 5' module of the A3'-SSA complex
分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ...
著者Cretu, C, Pena, V.
登録日2021-05-25
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
7OMF
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BU of 7omf by Molmil
Structure of a minimal SF3B core in complex with sudemycin D6 (form I)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2021-05-21
公開日2021-08-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Cretu, C, Schmitzova, J, Pena, V.
登録日2023-02-07
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
7B0I
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BU of 7b0i by Molmil
Structure of a minimal SF3B core in complex with spliceostatin A (form II)
分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3,Splicing factor 3B subunit 3,Splicing factor 3B subunit 3, ...
著者Cretu, C, Pena, V.
登録日2020-11-19
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors.
Nat Commun, 12, 2021
5IFE
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BU of 5ife by Molmil
Crystal structure of the human SF3b core complex
分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ...
著者Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V.
登録日2016-02-25
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Mol.Cell, 64, 2016
5M8C
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BU of 5m8c by Molmil
Spliceosome component
分子名称: Pre-mRNA-processing factor 19
著者Moura, T.R, Pena, V.
登録日2016-10-28
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018
6SP0
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BU of 6sp0 by Molmil
Structure of Esco2 acetyltransferase in complex with CoA
分子名称: COENZYME A, N-acetyltransferase ESCO2, ZINC ION
著者De, I, Pena, V.
登録日2019-08-30
公開日2020-07-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Alternative catalytic residues in the active site of Esco acetyltransferases
Sci Rep, 2020
5M89
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BU of 5m89 by Molmil
Spliceosome component
分子名称: Spliceosome WD40 Sc
著者Moura, T.R, Pena, V.
登録日2016-10-28
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.605 Å)
主引用文献Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
Mol. Cell, 69, 2018

 

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