3BXJ
| Crystal Structure of the C2-GAP Fragment of synGAP | 分子名称: | Ras GTPase-activating protein SynGAP | 著者 | Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K. | 登録日 | 2008-01-14 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. Embo Rep., 9, 2008
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3IM2
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3IM1
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2OG4
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3E9L
| Crystal Structure of Human Prp8, Residues 1755-2016 | 分子名称: | CHLORIDE ION, Pre-mRNA-processing-splicing factor 8, SODIUM ION | 著者 | Pena, V, Rozov, A, Wahl, M.C. | 登録日 | 2008-08-22 | 公開日 | 2008-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure and function of an RNase H domain at the heart of the spliceosome. Embo J., 27, 2008
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3E9O
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3E9P
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5HY7
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7OA3
| Crystal structure of Chili RNA aptamer in complex with DMHBO+ (Iridium hexammine co-crystallized form) | 分子名称: | Chili RNA Aptamer, DMHBO+, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Mieczkowski, M, Pena, V, Hoebartner, C. | 登録日 | 2021-04-19 | 公開日 | 2021-06-16 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
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7OAX
| Crystal structure of the Chili RNA aptamer in complex with DMHBO+ | 分子名称: | CHLORIDE ION, Chili RNA Aptamer, DMHBO+, ... | 著者 | Mieczkowski, M, Pena, V, Hoebartner, C. | 登録日 | 2021-04-20 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
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7OAW
| Crystal structure of the Chili RNA aptamer in complex with DMHBI+ | 分子名称: | CHLORIDE ION, Chili RNA Aptamer, DMHBI+, ... | 著者 | Mieczkowski, M, Pena, V, Hoebartner, C. | 登録日 | 2021-04-20 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
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7OAV
| Crystal structure of Chili RNA aptamer in complex with DMHBO+ (Iridium III hexammine soaking crystal form) | 分子名称: | CHLORIDE ION, Chili RNA Aptamer, DMHBO+, ... | 著者 | Mieczkowski, M, Pena, V, Hoebartner, C. | 登録日 | 2021-04-20 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine. Nat Commun, 12, 2021
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7B92
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7B9C
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7B91
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7QTT
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7OPI
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7ONB
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7OMF
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8CH6
| Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Cretu, C, Schmitzova, J, Pena, V. | 登録日 | 2023-02-07 | 公開日 | 2023-05-10 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural basis of catalytic activation in human splicing. Nature, 617, 2023
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7B0I
| Structure of a minimal SF3B core in complex with spliceostatin A (form II) | 分子名称: | PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3,Splicing factor 3B subunit 3,Splicing factor 3B subunit 3, ... | 著者 | Cretu, C, Pena, V. | 登録日 | 2020-11-19 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
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5IFE
| Crystal structure of the human SF3b core complex | 分子名称: | PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... | 著者 | Cretu, C, Dybkov, O, De Laurentiis, E, Will, C.L, Luhrmann, R, Pena, V. | 登録日 | 2016-02-25 | 公開日 | 2016-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. Mol.Cell, 64, 2016
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5M8C
| Spliceosome component | 分子名称: | Pre-mRNA-processing factor 19 | 著者 | Moura, T.R, Pena, V. | 登録日 | 2016-10-28 | 公開日 | 2018-02-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
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6SP0
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5M89
| Spliceosome component | 分子名称: | Spliceosome WD40 Sc | 著者 | Moura, T.R, Pena, V. | 登録日 | 2016-10-28 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.605 Å) | 主引用文献 | Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
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