3E9L

Crystal Structure of Human Prp8, Residues 1755-2016

Summary for 3E9L

• Entry DOI: 10.2210/pdb3e9l/pdb
• Related: 3E9O 3E9P
• Descriptor: Pre-mRNA-processing-splicing factor 8, SODIUM ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: nucleotidyl transfer, disease mutation, mrna processing, mrna splicing, nucleus, phosphoprotein, retinitis pigmentosa, rna-binding, sensory transduction, spliceosome, vision, rna binding protein, splicing
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus speckle (By similarity): Q6P2Q9
• Total number of polymer chains: 1
• Total formula weight: 29593.67

Authors

Pena, V.,Rozov, A.,Wahl, M.C. (deposition date: 2008-08-22, release date: 2008-10-07, Last modification date: 2024-02-21)

• Primary citation: Pena, V.,Rozov, A.,Fabrizio, P.,Luhrmann, R.,Wahl, M.C.; Structure and function of an RNase H domain at the heart of the spliceosome.; Embo J., 27:2929-2940, 2008; PubMed: 18843295; DOI: 10.1038/emboj.2008.209

Experimental method

X-RAY DIFFRACTION (1.95 Å)