2OG4

Structure of an expanded Jab1-MPN-like domain of splicing factor Prp8p from yeast

Summary for 2OG4

• Entry DOI: 10.2210/pdb2og4/pdb
• Descriptor: Pre-mRNA-splicing factor 8 (2 entities in total)
• Functional Keywords: isopeptidase, jab1/mpn domain, pre-mrna splicing, protein-protein interaction, prp8p, pseudoenzyme, spliceosome activation, u5-200k protein, protein binding
• Biological source: Saccharomyces cerevisiae
• Cellular location: Nucleus : P33334
• Total number of polymer chains: 1
• Total formula weight: 28743.52

Authors

Pena, V.,Liu, S.,Luehrmann, R.,Wahl, M.C. (deposition date: 2007-01-05, release date: 2007-03-13, Last modification date: 2023-12-27)

• Primary citation: Pena, V.,Liu, S.,Bujnicki, J.M.,Luhrmann, R.,Wahl, M.C.; Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.; Mol.Cell, 25:615-624, 2007; PubMed: 17317632; DOI: 10.1016/j.molcel.2007.01.023

Experimental method

X-RAY DIFFRACTION (2 Å)