2F1K
 
 | | Crystal structure of Synechocystis arogenate dehydrogenase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, prephenate dehydrogenase | | 著者 | Legrand, P, Dumas, R, Seux, M, Rippert, P, Ravelli, R, Ferrer, J.-L, Matringe, M. | | 登録日 | 2005-11-14 | | 公開日 | 2006-05-09 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Biochemical Characterization and Crystal Structure of Synechocystis Arogenate Dehydrogenase Provide Insights into Catalytic Reaction
Structure, 14, 2006
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5E7F
 | | Complex between lactococcal phage Tuc2009 RBP head domain and a nanobody (L06) | | 分子名称: | Major structural protein 1, nanobody L06 | | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | | 登録日 | 2015-10-12 | | 公開日 | 2015-12-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
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5E7T
 | | Structure of the tripod (BppUct-A-L) from the baseplate of bacteriophage Tuc2009 | | 分子名称: | CALCIUM ION, Major structural protein 1, Minor structural protein 4, ... | | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | | 登録日 | 2015-10-13 | | 公開日 | 2015-12-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
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5E7B
 | | Structure of a nanobody (vHH) from camel against phage Tuc2009 RBP (BppL, ORF53) | | 分子名称: | nanobody nano-L06 | | 著者 | Legrand, P, Collins, B, Blangy, S, Murphy, J, Spinelli, S, Gutierrez, C, Richet, N, Kellenberger, C, Desmyter, A, Mahony, J, van Sinderen, D, Cambillau, C. | | 登録日 | 2015-10-12 | | 公開日 | 2015-12-30 | | 最終更新日 | 2016-05-04 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
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2UY1
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4A6D
 | | Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM | | 分子名称: | GLYCEROL, HYDROXYINDOLE O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE, ... | | 著者 | Legrand, P, Haouz, A, Shepard, W. | | 登録日 | 2011-11-01 | | 公開日 | 2012-11-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway.
J.Pineal Res., 54, 2013
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4A6E
 | | Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM and N-acetylserotonin | | 分子名称: | GLYCEROL, HYDROXYINDOLE O-METHYLTRANSFERASE, N-ACETYL SEROTONIN, ... | | 著者 | Legrand, P, Haouz, A, Shepard, W. | | 登録日 | 2011-11-01 | | 公開日 | 2012-11-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway.
J.Pineal Res., 54, 2013
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4D5M
 | | Gonadotropin-releasing hormone agonist | | 分子名称: | PHOSPHATE ION, TRIPTORELIN | | 著者 | Legrand, P, Le Du, M.-H, Valery, C, Deville-Foillard, S, Paternostre, M, Artzner, F. | | 登録日 | 2014-11-05 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Atomic View of the Histidine Environment Stabilizing Higher- Ph Conformations of Ph-Dependent Proteins.
Nat.Commun., 6, 2015
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6T66
 | | Crystal structure of the Vibrio cholerae replicative helicase (DnaB) with GDP-AlF4 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... | | 著者 | Legrand, P, Quevillon-Cheruel, S, Li de la Sierra-Gallay, I, Walbott, H. | | 登録日 | 2019-10-17 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase.
Nucleic Acids Res., 49, 2021
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2V94
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7QXM
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8AAJ
 | | Crystal structure of the Pyrococcus abyssi RPA (apo form) | | 分子名称: | RPA14 subunit of the hetero-oligomeric complex involved in homologous recombination, RPA32 subunit of the hetero-oligomeric complex involved in homologous recombination, Replication factor A, ... | | 著者 | Legrand, P, Madru, C, Sauguet, L. | | 登録日 | 2022-07-01 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | DNA-binding mechanism and evolution of replication protein A.
Nat Commun, 14, 2023
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4C3H
 | | Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 | | 分子名称: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | | 著者 | Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. | | 登録日 | 2013-08-24 | | 公開日 | 2013-10-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Crystal Structure of the 14-Subunit RNA Polymerase I
Nature, 502, 2013
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3Q4F
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6Y1X
 | | X-ray structure of the radical SAM protein NifB, a key nitrogenase maturating enzyme | | 分子名称: | CHLORIDE ION, IRON/SULFUR CLUSTER, Radical SAM domain protein, ... | | 著者 | Sosa-Fajardo, A, Legrand, P, Paya-Tormo, L, Martin, L, Pellicer-Martinez, M.T, Echavarri-Erasun, C, Vernede, X, Rubio, L.M, Nicolet, Y. | | 登録日 | 2020-02-14 | | 公開日 | 2020-06-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
J.Am.Chem.Soc., 142, 2020
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4V96
 | | The structure of a 1.8 MDa viral genome injection device suggests alternative infection mechanisms | | 分子名称: | BPP, ORF46, ORF48 | | 著者 | Veesler, D, Spinelli, S, Mahony, J, Lichiere, J, Blangy, S, Bricogne, G, Legrand, P, Ortiz-Lombardia, M, Campanacci, V, van Sinderen, D, Cambillau, C. | | 登録日 | 2012-02-01 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4UUZ
 | | MCM2-histone complex | | 分子名称: | DNA REPLICATION LICENSING FACTOR MCM2, HISTONE H3, HISTONE H4 | | 著者 | Richet, N, Liu, D, Legrand, P, Bakail, M, Compper, C, Besle, A, Guerois, R, Ochsenbein, F. | | 登録日 | 2014-08-01 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Insight Into How the Human Helicase Subunit Mcm2 May Act as a Histone Chaperone Together with Asf1 at the Replication Fork.
Nucleic Acids Res., 43, 2015
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7BDX
 | | Armadillo domain of HSF2BP in complex with BRCA2 peptide | | 分子名称: | Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein, MAGNESIUM ION | | 著者 | Le Du, M.H, Zinn-Justin, S, Ghouil, R, Miron, S, Legrand, P. | | 登録日 | 2020-12-22 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Nat Commun, 12, 2021
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1MRQ
 | | Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone | | 分子名称: | Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R. | | 登録日 | 2002-09-18 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
J.Mol.Biol., 331, 2003
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2PNU
 | | Crystal structure of human androgen receptor ligand-binding domain in complex with EM-5744 | | 分子名称: | (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Cantin, L, Faucher, F, Couture, J.F, Pereira de Jesus-Tran, K, Legrand, P, Ciobanu, C.L, Singh, S.M, Labrie, F, Breton, R. | | 登録日 | 2007-04-25 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural Characterization of the Human Androgen Receptor Ligand-binding Domain Complexed with EM5744, a Rationally Designed Steroidal Ligand Bearing a Bulky Chain Directed toward Helix 12.
J.Biol.Chem., 282, 2007
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1XJB
 | | Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H), citrate and acetate molecules | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Aldo-keto reductase family 1 member C2, ... | | 著者 | Couture, J.-F, Pereira de Jesus-Tran, K, Roy, A.-M, Legrand, P, Cantin, L, Cote, P.-L, Luu-The, V, Labrie, F, Breton, R. | | 登録日 | 2004-09-23 | | 公開日 | 2005-06-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen
Protein Sci., 14, 2005
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1HFE
 | | 1.6 A RESOLUTION STRUCTURE OF THE FE-ONLY HYDROGENASE FROM DESULFOVIBRIO DESULFURICANS | | 分子名称: | 1,3-PROPANEDITHIOL, CARBON MONOXIDE, CYANIDE ION, ... | | 著者 | Nicolet, Y, Piras, C, Legrand, P, Hatchikian, E.C, Fontecilla-Camps, J.C. | | 登録日 | 1998-11-11 | | 公開日 | 1999-04-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center.
Structure Fold.Des., 7, 1999
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8QQE
 | | Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2 | | 分子名称: | Breast cancer type 2 susceptibility protein, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Miron, S, Legrand, P, Zinn-Justin, S. | | 登録日 | 2023-10-04 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.461 Å) | | 主引用文献 | DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces.
Nucleic Acids Res., 52, 2024
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1EYX
 | | CRYSTAL STRUCTURE OF R-PHYCOERYTHRIN AT 2.2 ANGSTROMS | | 分子名称: | BILIVERDINE IX ALPHA, PHYCOCYANOBILIN, PHYCOUROBILIN, ... | | 著者 | Contreras-Martel, C, Legrand, P, Piras, C, Vernede, X, Martinez-Oyanedel, J, Bunster, M, Fontecilla-Camps, J.C. | | 登録日 | 2000-05-09 | | 公開日 | 2000-11-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystallization and 2.2 A resolution structure of R-phycoerythrin from Gracilaria chilensis: a case of perfect hemihedral twinning.
Acta Crystallogr.,Sect.D, 57, 2001
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2YOE
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam | | 分子名称: | CYS-LOOP LIGAND-GATED ION CHANNEL, Flurazepam, GAMMA-AMINO-BUTANOIC ACID | | 著者 | Spurny, R, Brams, M, Nury, H, Legrand, P, Ulens, C. | | 登録日 | 2012-10-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
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