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7BDX

Armadillo domain of HSF2BP in complex with BRCA2 peptide

Summary for 7BDX
Entry DOI10.2210/pdb7bdx/pdb
DescriptorHeat shock factor 2-binding protein, Breast cancer type 2 susceptibility protein, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordshsf2bp, brca2, nuclear protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight108922.85
Authors
Le Du, M.H.,Zinn-Justin, S.,Ghouil, R.,Miron, S.,Legrand, P. (deposition date: 2020-12-22, release date: 2021-07-07, Last modification date: 2022-07-20)
Primary citationGhouil, R.,Miron, S.,Koornneef, L.,Veerman, J.,Paul, M.W.,Le Du, M.H.,Sleddens-Linkels, E.,van Rossum-Fikkert, S.E.,van Loon, Y.,Felipe-Medina, N.,Pendas, A.M.,Maas, A.,Essers, J.,Legrand, P.,Baarends, W.M.,Kanaar, R.,Zinn-Justin, S.,Zelensky, A.N.
BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Nat Commun, 12:4605-4605, 2021
Cited by
PubMed: 34326328
DOI: 10.1038/s41467-021-24871-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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