8QQE

Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2

Summary for 8QQE

Entry DOI	10.2210/pdb8qqe/pdb
Descriptor	Meiotic recombination protein DMC1/LIM15 homolog, Breast cancer type 2 susceptibility protein, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	dna binding protein, meiotic recombination, ring protein, octamer, aaa atpase, recombination
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	80046.41
Authors	Miron, S.,Legrand, P.,Zinn-Justin, S. (deposition date: 2023-10-04, release date: 2024-06-19)
Primary citation	Miron, S.,Legrand, P.,Dupaigne, P.,van Rossum-Fikkert, S.E.,Ristic, D.,Majeed, A.,Kanaar, R.,Zinn-Justin, S.,Zelensky, A.N. DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces. Nucleic Acids Res., 2024 Cited by PubMed: 38828772 DOI: 10.1093/nar/gkae452 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.461 Å)

Structure validation