4A6E
Crystal structure of human N-acetylserotonin methyltransferase (ASMT) in complex with SAM and N-acetylserotonin
Summary for 4A6E
Entry DOI | 10.2210/pdb4a6e/pdb |
Related | 4A6D |
Descriptor | HYDROXYINDOLE O-METHYLTRANSFERASE, ZINC ION, S-ADENOSYLMETHIONINE, ... (7 entities in total) |
Functional Keywords | transferase, melatonin, circadian clock |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 40829.37 |
Authors | Legrand, P.,Haouz, A.,Shepard, W. (deposition date: 2011-11-01, release date: 2012-11-07, Last modification date: 2024-05-08) |
Primary citation | Botros, H.G.,Legrand, P.,Pagan, C.,Bondet, V.,Weber, P.,Ben-Abdallah, M.,Lemiere, N.,Huguet, G.,Bellalou, J.,Maronde, E.,Beguin, P.,Haouz, A.,Shepard, W.,Bourgeron, T. Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway. J.Pineal Res., 54:46-, 2013 Cited by PubMed: 22775292DOI: 10.1111/J.1600-079X.2012.01020.X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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