8SXB
 
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8SWN
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8SXA
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4IP8
 | | Structure of human serum amyloid A1 | | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SULFATE ION, Serum amyloid A-1 protein | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2013-01-09 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.193 Å) | | 主引用文献 | Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4IP9
 | | Structure of native human serum amyloid A1 | | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, Serum amyloid A-1 protein | | 著者 | Lu, J, Sun, P.D. | | 登録日 | 2013-01-09 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6SCT
 | | Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex | | 分子名称: | Clathrin heavy chain, Clathrin light chain | | 著者 | Morris, K.L, Cameron, A.D, Sessions, R, Smith, C.J. | | 登録日 | 2019-07-25 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.69 Å) | | 主引用文献 | Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
Nat.Struct.Mol.Biol., 26, 2019
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8IL0
 | | Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 | | 分子名称: | Glycosyltransferase | | 著者 | Dai, Y, Li, P, Qiao, H, Xia, M, Liu, W, Fang, P. | | 登録日 | 2023-03-01 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
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8ILA
 | | Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 in complex with substrates | | 分子名称: | (2~{S})-3-[2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-[(1~{R},2~{R})-1-azanyl-2-oxidanyl-propyl]-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-1~{H}-imidazol-5-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid, GUANOSINE-5'-DIPHOSPHATE, Glycosyltransferase | | 著者 | Dai, Y, Qiao, H, Xia, M, Fang, P, Liu, W. | | 登録日 | 2023-03-03 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
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3J9J
 | | Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy | | 分子名称: | Transient receptor potential cation channel subfamily V member 1 | | 著者 | Wang, R.Y.-R, Barad, B.A, Fraser, J.S, DiMaio, F. | | 登録日 | 2015-02-02 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.275 Å) | | 主引用文献 | EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015
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7DNR
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3JAF
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state | | 分子名称: | (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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3JAD
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, strychnine-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, STRYCHNINE | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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1OGU
 | | STRUCTURE OF HUMAN THR160-PHOSPHO CDK2/CYCLIN A COMPLEXED WITH A 2-ARYLAMINO-4-CYCLOHEXYLMETHYL-5-NITROSO-6-AMINOPYRIMIDINE INHIBITOR | | 分子名称: | 4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, ... | | 著者 | Pratt, D.J, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2003-05-13 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Based Design of 2-Arylamino-4-Cyclohexyl Methyl-5-Nitroso-6-Aminopyrimidine Inhibitors of Cyclin-Dependent Kinases 1 and 2
Bioorg.Med.Chem.Lett., 13, 2003
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3JAE
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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3EFK
 | | Structure of c-Met with pyrimidone inhibitor 50 | | 分子名称: | 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-2-[(4-fluorophenyl)amino]-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor | | 著者 | Bellon, S.F, D'Angelo, N, Whittington, D, Dussault, I. | | 登録日 | 2008-09-09 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
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3EFJ
 | | Structure of c-Met with pyrimidone inhibitor 7 | | 分子名称: | 2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methylpyrimidin-4(3H)-one, Hepatocyte growth factor receptor | | 著者 | D'Angelo, N, Bellon, S, Whittington, D. | | 登録日 | 2008-09-09 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design, synthesis, and biological evaluation of potent c-Met inhibitors.
J.Med.Chem., 51, 2008
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8TBQ
 | | The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of pH-selective anti-VISTA antibody | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SNS-101 Fab heavy chain, ... | | 著者 | van der Horst, E.H, Mukherjee, A, Thisted, T. | | 登録日 | 2023-06-29 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.593 Å) | | 主引用文献 | VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response.
Nat Commun, 15, 2024
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4LWS
 | | EsxA : EsxB (SeMet) hetero-dimer from Thermomonospora curvata | | 分子名称: | ACETATE ION, GLYCEROL, Uncharacterized protein | | 著者 | Dovala, D.L, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | | 登録日 | 2013-07-28 | | 公開日 | 2015-02-04 | | 最終更新日 | 2016-09-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
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4N1A
 | | Thermomonospora curvata EccC (ATPases 2 and 3) in complex with a signal sequence peptide | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell divisionFtsK/SpoIIIE, MAGNESIUM ION, ... | | 著者 | Dovala, D.L, Bendebury, A, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | | 登録日 | 2013-10-03 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
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7CJG
 | | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase | | 分子名称: | 5,6-DIMETHYLBENZIMIDAZOLE, GLYCEROL, Glutamine cyclotransferase-related protein, ... | | 著者 | Ruiz-Carrillo, D, Lamers, S, Feng, Q, Yu, S, Sun, B, Jiang, J, Lukman, M. | | 登録日 | 2020-07-10 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase.
Biol.Chem., 402, 2021
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7CJE
 | | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase | | 分子名称: | GLYCEROL, Glutamine cyclotransferase-related protein, MAGNESIUM ION, ... | | 著者 | Ruiz-Carrillo, D, Lamers, S, Feng, Q, Yu, S, Sun, B, Jiang, J, Lukman, M. | | 登録日 | 2020-07-10 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.950007 Å) | | 主引用文献 | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase.
Biol.Chem., 402, 2021
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4LYA
 | | EssC (ATPases 2 and 3) from Geobacillus thermodenitrificans (SeMet) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein | | 著者 | Dovala, D.L, Bendebury, A, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | | 登録日 | 2013-07-30 | | 公開日 | 2015-02-04 | | 最終更新日 | 2016-09-21 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
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4NH0
 | | Cytoplasmic domain of the Thermomonospora curvata Type VII Secretion ATPase EccC | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell divisionFtsK/SpoIIIE, MAGNESIUM ION, ... | | 著者 | Rosenberg, O.S, Cox, J.S, Stroud, R.M, Strauli, N, Dovala, D. | | 登録日 | 2013-11-03 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
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4JPO
 | | 5A resolution structure of Proteasome Assembly Chaperone Hsm3 in complex with a C-terminal fragment of Rpt1 | | 分子名称: | 26S protease regulatory subunit 7 homolog, DNA mismatch repair protein HSM3 | | 著者 | Lovell, S, Battaile, K.P, Singh, R, Roelofs, J. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Reconfiguration of the proteasome during chaperone-mediated assembly.
Nature, 497, 2013
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8YGH
 | | pP1192R-apo open state | | 分子名称: | DNA topoisomerase 2 | | 著者 | Sun, J.Q, Liu, R.L. | | 登録日 | 2024-02-26 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis for difunctional mechanism of m-AMSA against African swine fever virus pP1192R.
Nucleic Acids Res., 2024
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