7DZ9
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![BU of 7dz9 by Molmil](/molmil-images/mine/7dz9) | MbnABC complex | 分子名称: | FE (III) ION, MbnA, MbnB, ... | 著者 | Chao, D, Dan, Z, Yijun, G, Wei, C. | 登録日 | 2021-01-25 | 公開日 | 2022-03-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis. Cell Res., 32, 2022
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5XZ9
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![BU of 5xz9 by Molmil](/molmil-images/mine/5xz9) | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent 6-phosphofructokinase, GLYCEROL | 著者 | Wang, C.L, Tian, T, Zang, J.Y. | 登録日 | 2017-07-12 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion. Biochemistry, 57, 2018
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5XZ7
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![BU of 5xz7 by Molmil](/molmil-images/mine/5xz7) | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ATP-dependent 6-phosphofructokinase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wang, C.L, Tian, T, Zang, J.Y. | 登録日 | 2017-07-11 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion. Biochemistry, 57, 2018
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4R68
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![BU of 4r68 by Molmil](/molmil-images/mine/4r68) | Lactate Dehydrogenase in complex with inhibitor compound 31 | 分子名称: | (1S)-1-phenylethyl (4-chloro-3-{[(4S)-4-(2,6-dichlorophenyl)-2-hydroxy-6-oxocyclohex-1-en-1-yl]sulfanyl}phenyl)acetate, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2014-08-22 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | 主引用文献 | Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 25, 2014
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5XZA
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![BU of 5xza by Molmil](/molmil-images/mine/5xza) | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, CITRATE ANION, ... | 著者 | Wang, C.L, Tian, T, Zang, J.Y. | 登録日 | 2017-07-12 | 公開日 | 2019-03-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion. Biochemistry, 57, 2018
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5XZ8
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![BU of 5xz8 by Molmil](/molmil-images/mine/5xz8) | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate (the ATP analog) and fructose-6-phosphate | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, ATP-dependent 6-phosphofructokinase, GLYCEROL, ... | 著者 | Wang, C.L, Tian, T, Zang, J.Y. | 登録日 | 2017-07-11 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion. Biochemistry, 57, 2018
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5XZ6
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![BU of 5xz6 by Molmil](/molmil-images/mine/5xz6) | Crystal Structure of Phosphofructokinase from Staphylococcus aureus in complex with adenylylimidodiphosphate, the ATP analogue | 分子名称: | ATP-dependent 6-phosphofructokinase, GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Wang, C.L, Tian, T, Zang, J.Y. | 登録日 | 2017-07-11 | 公開日 | 2019-02-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Insights into the Regulation of Staphylococcus aureus Phosphofructokinase by Tetramer-Dimer Conversion. Biochemistry, 57, 2018
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7FC0
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![BU of 7fc0 by Molmil](/molmil-images/mine/7fc0) | Reconstitution of MbnABC complex from Rugamonas rubra ATCC-43154 (GroupIII) | 分子名称: | FE (III) ION, Methanobactin biosynthesis cassette protein MbnB, Methanobactin biosynthesis cassette protein MbnC, ... | 著者 | Chao, D, Zhaolin, L, Shoujie, L, Li, Z, Dan, Z, Ying, J, Wei, C. | 登録日 | 2021-07-13 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.643 Å) | 主引用文献 | Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis. Cell Res., 32, 2022
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4QO8
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![BU of 4qo8 by Molmil](/molmil-images/mine/4qo8) | Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 104 | 分子名称: | (5S)-2-[(2-chlorophenyl)sulfanyl]-5-(2,6-dichlorophenyl)-3-hydroxycyclohex-2-en-1-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2014-06-19 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 24, 2014
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8W4V
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![BU of 8w4v by Molmil](/molmil-images/mine/8w4v) | Crystal structure of human HSP90 in complex with compound 4 | 分子名称: | 4-[2-[(dimethylamino)methyl]phenyl]sulfanylbenzene-1,3-diol, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-08-25 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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8W8K
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![BU of 8w8k by Molmil](/molmil-images/mine/8w8k) | Crystal structures of HSP90 and the compound Ganetespid in the "closed" conformation | 分子名称: | 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-09-03 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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7F29
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![BU of 7f29 by Molmil](/molmil-images/mine/7f29) | |
8K5N
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![BU of 8k5n by Molmil](/molmil-images/mine/8k5n) | |
4RE1
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![BU of 4re1 by Molmil](/molmil-images/mine/4re1) | |
5Z8S
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![BU of 5z8s by Molmil](/molmil-images/mine/5z8s) | |
5Z91
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![BU of 5z91 by Molmil](/molmil-images/mine/5z91) | Human mitochondrial ferritin mutant bound with gold ions | 分子名称: | Ferritin, mitochondrial, GOLD ION, ... | 著者 | Zang, J, Zheng, B, Zhao, G. | 登録日 | 2018-02-01 | 公開日 | 2019-02-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | Design and site-directed compartmentalization of gold nanoclusters within the intrasubunit interfaces of ferritin nanocage. J Nanobiotechnology, 17, 2019
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5Z8U
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![BU of 5z8u by Molmil](/molmil-images/mine/5z8u) | |
5Z8J
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![BU of 5z8j by Molmil](/molmil-images/mine/5z8j) | |
8KI4
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![BU of 8ki4 by Molmil](/molmil-images/mine/8ki4) | Crystal structure of human HSP90 in intermediate state | 分子名称: | 1,2-ETHANEDIOL, Heat shock protein HSP 90-alpha | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-08-22 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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4GQ9
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![BU of 4gq9 by Molmil](/molmil-images/mine/4gq9) | Chikungunya virus neutralizing antibody 9.8B Fab fragment | 分子名称: | Chikungunya virus neutralizing antibody 9.8B Fab fragment heavy chain, Chikungunya virus neutralizing antibody 9.8B Fab fragment light chain | 著者 | Sun, S, Rossmann, M.G. | 登録日 | 2012-08-22 | 公開日 | 2013-07-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.995 Å) | 主引用文献 | Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
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4R69
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![BU of 4r69 by Molmil](/molmil-images/mine/4r69) | Lactate Dehydrogenase in complex with inhibitor compound 13 | 分子名称: | (5R)-2-[(2-chlorophenyl)sulfanyl]-5-[2,6-dichloro-3-(tetrahydro-2H-pyran-4-ylamino)phenyl]-3-hydroxycyclohex-2-en-1-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2014-08-22 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 25, 2014
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4QO7
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![BU of 4qo7 by Molmil](/molmil-images/mine/4qo7) | |
7MOA
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![BU of 7moa by Molmil](/molmil-images/mine/7moa) | Cryo-EM structure of the c-MET II/HGF I complex bound with HGF II in a rigid conformation | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor receptor | 著者 | Uchikawa, E, Chen, Z.M, Xiao, G.Y, Zhang, X.W, Bai, X.C. | 登録日 | 2021-05-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structural basis of the activation of c-MET receptor. Nat Commun, 12, 2021
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7MOB
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![BU of 7mob by Molmil](/molmil-images/mine/7mob) | Cryo-EM structure of 2:2 c-MET/NK1 complex | 分子名称: | Hepatocyte growth factor, Hepatocyte growth factor receptor | 著者 | Uchikawa, E, Chen, Z.M, Xiao, G.Y, Zhang, X.W, Bai, X.C. | 登録日 | 2021-05-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Structural basis of the activation of c-MET receptor. Nat Commun, 12, 2021
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7MO8
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![BU of 7mo8 by Molmil](/molmil-images/mine/7mo8) | Cryo-EM structure of 1:1 c-MET I/HGF I complex after focused 3D refinement of holo-complex | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor receptor | 著者 | Uchikawa, E, Chen, Z.M, Xiao, G.Y, Zhang, X.W, Bai, X.C. | 登録日 | 2021-05-01 | 公開日 | 2021-06-09 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural basis of the activation of c-MET receptor. Nat Commun, 12, 2021
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