7JZI
 
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7JZ4
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7JZK
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7JZ1
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4GW4
 | | Crystal structure of 3BNC60 Fab with P61A mutation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC60 Fab Heavy-chain, 3BNC60 Fab Light-chain | | 著者 | Diskin, R, Fu, B.Z, Bjorkman, P.J. | | 登録日 | 2012-08-31 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
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6C6X
 | | Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque. | | 分子名称: | JC57-14 Heavy chain, JC57-14 Light chain | | 著者 | Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D. | | 登録日 | 2018-01-19 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
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6C6Z
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6C6Y
 | | Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain | | 分子名称: | JC57-14 Heavy chain, JC57-14 Light chain, SULFATE ION, ... | | 著者 | Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D. | | 登録日 | 2018-01-19 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
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9CJZ
 | | CryoEM structure of NC99 hemagglutinin trimer in complex with Fab T009 3-E04 | | 分子名称: | 3-E04 Heavy chain, 3-E04 Light chain, Hemagglutinin HA1 chain, ... | | 著者 | Li, N, Tsybovsky, Y, Sangesland, M, Kanekiyo, M. | | 登録日 | 2024-07-08 | | 公開日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques.
Biorxiv, 2025
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9CJY
 | | CryoEM structure of NC99 hemagglutinin trimer in complex with Fab BB798E 3-C07 | | 分子名称: | 3-C07 Heavy chain, 3-C07 Light chain, Hemagglutinin HA1 chain, ... | | 著者 | Li, N, Tsybovsky, Y, Sangesland, M, Kanekiyo, M. | | 登録日 | 2024-07-08 | | 公開日 | 2025-07-09 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Functional, Immunogenetic, and Structural Convergence in Influenza Immunity between Humans and Macaques.
Biorxiv, 2025
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3LRS
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6MQC
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6MPH
 | | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ... | | 著者 | Acharya, P, Xu, K, Kwong, P.D. | | 登録日 | 2018-10-06 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
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6MJZ
 | | Cryo-EM structure of Human Parainfluenza Virus Type 3 (hPIV3) in complex with antibody PIA174 | | 分子名称: | Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain | | 著者 | Acharya, P, Stewart-Jones, G, Carragher, B, Potter, C.S, Kwong, P.D. | | 登録日 | 2018-09-24 | | 公開日 | 2018-11-14 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6MQM
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6N16
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6N1W
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6NF2
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6MQE
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6MQS
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6MQR
 | | Vaccine-elicited NHP FP-targeting neutralizing antibody 0PV-a.01 in complex with FP (residue 512-519) | | 分子名称: | CALCIUM ION, HIV fusion peptide residue 512-519, SULFATE ION, ... | | 著者 | Xu, K, Wang, Y, Kwong, P.D. | | 登録日 | 2018-10-10 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
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6N1V
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6MPG
 | | Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ... | | 著者 | Acharya, P, Kwong, P.D. | | 登録日 | 2018-10-06 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
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3U1S
 | | Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ... | | 著者 | Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
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3TIH
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