1L3R
| Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | 著者 | Madhusudan, Akamine, P, Xuong, N.-H, Taylor, S.S. | 登録日 | 2002-02-28 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase. Nat.Struct.Biol., 9, 2002
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1BX6
| CRYSTAL STRUCTURE OF THE POTENT NATURAL PRODUCT INHIBITOR BALANOL IN COMPLEX WITH THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE | 分子名称: | BALANOL, CAMP-DEPENDENT PROTEIN KINASE | 著者 | Narayana, N, Xuong, N.-H, Ten Eyck, L.F, Taylor, S.S. | 登録日 | 1998-10-13 | 公開日 | 1999-04-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase. Biochemistry, 38, 1999
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1BKX
| A BINARY COMPLEX OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND ADENOSINE FURTHER DEFINES CONFORMATIONAL FLEXIBILITY | 分子名称: | ADENOSINE MONOPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE | 著者 | Narayana, N, Cox, S, Xuong, N, Ten Eyck, L.F, Taylor, S.S. | 登録日 | 1997-07-01 | 公開日 | 1998-03-18 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility. Structure, 5, 1997
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6DHA
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2JTK
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6ONJ
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6ONI
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6PDZ
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9IOZ
| Structure of the bacteriophage T5 tail tip complex | 分子名称: | Baseplate hub protein pb3, Baseplate tube protein p140, Distal tail protein pb9 | 著者 | Peng, Y.N, Liu, H.R. | 登録日 | 2024-07-10 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection. Int J Mol Sci, 25, 2024
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9ILV
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9INY
| Structure of bacteriophage T5 tail tube | 分子名称: | Tail tube protein pb6 | 著者 | Peng, Y.N, Liu, H.R. | 登録日 | 2024-07-08 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of Mature and Urea-Treated Empty Bacteriophage T5: Insights into Siphophage Infection and DNA Ejection. Int J Mol Sci, 25, 2024
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5Y83
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5Y82
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6V2F
| Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting inhibitor, GS-6207 | 分子名称: | HIV-1 capsid, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide | 著者 | Appleby, T.C, Link, J.O, Yant, S.R, Villasenor, A.G, Somoza, J.R, Hu, E.Y, Schroeder, S.D, Cihlar, T. | 登録日 | 2019-11-22 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature, 584, 2020
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1BAK
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5WQT
| Structure of a protein involved in pyroptosis | 分子名称: | CITRIC ACID, GLYCEROL, Gasdermin-D | 著者 | Kuang, S, Li, J. | 登録日 | 2016-11-28 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1CKB
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1CKA
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1RDQ
| Hydrolysis of ATP in the crystal of Y204A mutant of cAMP-dependent protein kinase | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Yang, J, Ten Eyck, L.F, Xuong, N.H, Taylor, S.S. | 登録日 | 2003-11-05 | 公開日 | 2004-04-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26A: New Insights into the Catalytic Mechanism. J.Mol.Biol., 336, 2004
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7KM5
| Crystal structure of SARS-CoV-2 RBD complexed with Nanosota-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Spike protein S1, ... | 著者 | Ye, G, Shi, K, Aihara, H, Li, F. | 登録日 | 2020-11-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | The development of Nanosota - 1 as anti-SARS-CoV-2 nanobody drug candidates. Elife, 10, 2021
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5X0R
| Crystal Structure of PXR LBD Complexed with SJB7 | 分子名称: | 4-[(4-tert-butylphenyl)sulfonyl]-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole, Nuclear receptor coactivator 1, Nuclear receptor subfamily 1 group I member 2 | 著者 | Lv, L, Lin, W, Chai, S.C, Zhang, Q, Chen, T. | 登録日 | 2017-01-23 | 公開日 | 2017-10-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.665 Å) | 主引用文献 | SPA70 is a potent antagonist of human pregnane X receptor. Nat Commun, 8, 2017
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3EAA
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1AWO
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6CDS
| Human neurofibromin 2/merlin/schwannomin residues 1-339 in complex with PIP2 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Merlin, ... | 著者 | Chinthalapudi, K, Sharff, A.J, Bricogne, G, Izard, T. | 登録日 | 2018-02-09 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2. Nat Commun, 9, 2018
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5ID6
| Structure of Cpf1/RNA Complex | 分子名称: | Cpf1, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3') | 著者 | Dong, D, Ren, K, Qiu, X, Wang, J, Huang, Z. | 登録日 | 2016-02-24 | 公開日 | 2016-04-27 | 最終更新日 | 2016-05-11 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | The crystal structure of Cpf1 in complex with CRISPR RNA Nature, 532, 2016
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