2YQ6
| Structure of Bcl-xL bound to BimSAHB | 分子名称: | BCL-2-LIKE PROTEIN 1, BIM BETA 5, GLYCEROL | 著者 | Smith, B.J, Czabotar, P.E. | 登録日 | 2012-11-06 | 公開日 | 2012-11-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity. Acs Chem.Biol., 8, 2013
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2KP1
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2KP2
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3W1Z
| Heat shock protein 16.0 from Schizosaccharomyces pombe | 分子名称: | Heat shock protein 16 | 著者 | Hanazono, Y, Takeda, K, Akiyama, N, Aikawa, Y, Miki, K. | 登録日 | 2012-11-26 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, from Schizosaccharomyces pombe Structure, 21, 2013
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7BWI
| Solution structure of recombinant APETx1 | 分子名称: | Kappa-actitoxin-Ael2a | 著者 | Matsumura, K, Kobayashi, N, Kurita, J, Nishimura, Y, Yokogawa, M, Imai, S, Shimada, I, Osawa, M. | 登録日 | 2020-04-14 | 公開日 | 2020-12-23 | 最終更新日 | 2021-07-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization. Bmc Mol Cell Biol, 22, 2021
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5YJ9
| Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ... | 著者 | Okatsu, K, Sato, Y, Fukai, S. | 登録日 | 2017-10-09 | 公開日 | 2018-07-25 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural insights into ubiquitin phosphorylation by PINK1. Sci Rep, 8, 2018
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2DXS
| Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor | 分子名称: | Genome polyprotein, N-[(13-CYCLOHEXYL-6,7-DIHYDROINDOLO[1,2-D][1,4]BENZOXAZEPIN-10-YL)CARBONYL]-2-METHYL-L-ALANINE | 著者 | Adachi, T, Tsuruha, J, Doi, S, Murase, K, Ikegashira, K, Watanabe, S, Uehara, K, Orita, T, Nomura, A, Kamada, M. | 登録日 | 2006-08-30 | 公開日 | 2006-12-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of Conformationally Constrained Tetracyclic Compounds as Potent Hepatitis C Virus NS5B RNA Polymerase Inhibitors J.Med.Chem., 49, 2006
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7V5N
| Crystal structure of Fab fragment of bevacizumab bound to DNA aptamer | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*GP*TP*TP*GP*GP*TP*GP*GP*TP*AP*GP*TP*TP*AP*CP*GP*TP*TP*CP*GP*C)-3'), IMIDAZOLE, ... | 著者 | Hishiki, A, Tong, J, Todoroki, K, Hashimoto, H. | 登録日 | 2021-08-17 | 公開日 | 2022-02-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection. Biosens.Bioelectron., 203, 2022
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2Z6D
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2Z6C
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4ZY3
| Crystal Structure of Keap1 in Complex with a small chemical compound, K67 | 分子名称: | FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | 著者 | Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M. | 登録日 | 2015-05-21 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Nat Commun, 7, 2016
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8IG1
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7YV1
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | 著者 | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.454 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YUZ
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | 分子名称: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2022-08-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | 主引用文献 | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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2RDV
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7DB0
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in dimedone-bound form | 分子名称: | 5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE, DIMETHYL SULFOXIDE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DB1
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in dimedone- and glutathione-bound form | 分子名称: | 5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DAZ
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP015- and GSH-bound form | 分子名称: | 6-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)pyridin-3-amine, GLUTATHIONE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DB2
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in GS-dimedone-bound form | 分子名称: | 5,5-DIMETHYLCYCLOHEXANE-1,3-DIONE, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DAY
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP013-, and GSH-bound form | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-[(5-tert-butyl-2-methyl-phenyl)sulfonylamino]benzoic acid, GLUTATHIONE, ... | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DB4
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP012- and glutathione-bound form | 分子名称: | 1-[(4-fluorophenyl)methyl]-2,2-bis(oxidanylidene)thieno[3,2-c][1,2]thiazin-4-one, GLUTATHIONE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DAX
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP013-bound form | 分子名称: | 2-[(5-tert-butyl-2-methyl-phenyl)sulfonylamino]benzoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7000097 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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7DB3
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in TDP011-bound form | 分子名称: | 4-bromanyl-2-[[2-[(E)-1-(3-methoxyphenyl)ethylideneamino]propan-2-ylamino]methyl]phenol, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | 著者 | Koiwai, K, Inaba, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2020-10-18 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S -transferase Noppera-bo J Pestic Sci, 46, 2021
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8I34
| The crystal structure of EPD-BCP1 from a marine sponge | 分子名称: | (2~{Z},4~{E},6~{E},8~{E},10~{E},12~{E},14~{E},16~{E})-4,8,13,17-tetramethyl-3-oxidanyl-19-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]-1-[(1~{R},4~{S})-1,2,2-trimethyl-4-oxidanyl-cyclopentyl]nonadeca-2,4,6,8,10,12,14,16-octaen-18-yn-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ASTAXANTHIN, ... | 著者 | Shomura, Y, Kawasaki, S. | 登録日 | 2023-01-16 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | An ependymin-related blue carotenoprotein decorates marine blue sponge. J.Biol.Chem., 299, 2023
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7DC7
| Crystal structure of D12 Fab-ATP complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, D12 Fab heavy chain, D12 Fab light chain | 著者 | Kawauchi, H, Fukami, T.A, Tatsumi, K, Torizawa, T, Mimoto, F. | 登録日 | 2020-10-23 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment. Cell Rep, 33, 2020
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