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7EJX
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BU of 7ejx by Molmil
Structure of the GPR88-Gi1 signaling complex bound to a synthetic ligand
分子名称: (1R,2R)-N-[(2S,3S)-2-azanyl-3-methyl-pentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-yl-cyclopropane-1-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, J, Chen, G, Liu, Z, Du, Y.
登録日2021-04-02
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.
Nat Commun, 13, 2022
7EJ0
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BU of 7ej0 by Molmil
Structure of the alpha2A-adrenergic receptor GoA signaling complex
分子名称: Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, J, Cao, S, Liu, Z, Du, Y.
登録日2021-04-01
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8, 2022
7EJA
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Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to dexmedetomidine
分子名称: 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, J, Cao, S, Liu, Z, Du, Y.
登録日2021-04-01
公開日2022-04-13
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8, 2022
7EJ8
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BU of 7ej8 by Molmil
Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to brimonidine
分子名称: Alpha-2A adrenergic receptor, Brimonidine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Xu, J, Cao, S, Liu, Z, Du, Y.
登録日2021-04-01
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8, 2022
7EJK
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BU of 7ejk by Molmil
Structure of the alpha2A-adrenergic receptor GoA signaling complex bound to oxymetazoline
分子名称: Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Xu, J, Cao, S, Liu, Z, Du, Y.
登録日2021-04-02
公開日2022-04-13
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8, 2022
7F09
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BU of 7f09 by Molmil
Crystal structure of the HLH-Lz domain of human TFE3
分子名称: 1,2-ETHANEDIOL, Transcription factor E3, ZINC ION
著者Yang, G, Li, P, Liu, Z, Wu, S, Zhuang, C, Qiao, H, Fang, P, Wang, J.
登録日2021-06-03
公開日2021-07-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the dimerization mechanism of human transcription factor E3.
Biochem.Biophys.Res.Commun., 569, 2021
7D0L
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BU of 7d0l by Molmil
The major capsid of Omono River virus (strain:LZ), protrusion-free status.
分子名称: Capsid protein
著者Shao, Q, Jia, X, Gao, Y, Liu, Z.
登録日2020-09-11
公開日2021-03-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.
Plos Pathog., 17, 2021
7CZ6
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BU of 7cz6 by Molmil
Protrusion structure of Omono River virus
分子名称: Capsid protein
著者Shao, Q, Jia, X, Gao, Y, Liu, Z.
登録日2020-09-07
公開日2021-03-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.
Plos Pathog., 17, 2021
7D0K
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BU of 7d0k by Molmil
The icosahedral capsid of Omono River virus (strain:LZ)
分子名称: Capsid protein
著者Shao, Q, Jia, X, Gao, Y, Liu, Z.
登録日2020-09-11
公開日2021-03-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.
Plos Pathog., 17, 2021
7YCA
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BU of 7yca by Molmil
Cryo-EM structure of the PSI-LHCI-Lhcp supercomplex from Ostreococcus tauri
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
著者Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z.
登録日2022-07-01
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers.
Elife, 12, 2023
7WZ4
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BU of 7wz4 by Molmil
Structure of an orphan GPCR-G protein signaling complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Xu, J, Chen, G, Liu, Z, Du, Y.
登録日2022-02-17
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.
Nat Commun, 13, 2022
7YGI
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BU of 7ygi by Molmil
Crystal structure of p53 DBD domain in complex with azurin
分子名称: Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ...
著者Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q.
登録日2022-07-11
公開日2023-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Commun Biol, 6, 2023
8WU3
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BU of 8wu3 by Molmil
Crystal structure of RNA-dependent RNA polymerases from Alongshan virus
分子名称: RNA polymerase
著者Liu, Z.Y, Han, P, Peng, Q, Qi, J.X.
登録日2023-10-20
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of RNA-dependent RNA polymerases from Jingmen tick virus and Alongshan virus
HLIFE, 2, 2024
7V2A
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BU of 7v2a by Molmil
SARS-CoV-2 Spike trimer in complex with XG014 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, The heavy chain of XG014, ...
著者Wang, K, Wang, X, Pan, L.
登録日2021-08-07
公開日2021-10-20
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
7V26
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BU of 7v26 by Molmil
XG005-bound SARS-CoV-2 S
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, XG005 Heavy chain, ...
著者Zhan, W.Q, Zhang, X, Sun, L, Chen, Z.G.
登録日2021-08-07
公開日2021-10-20
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献An ultrapotent pan-beta-coronavirus lineage B ( beta-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope.
Protein Cell, 13, 2022
6KVJ
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BU of 6kvj by Molmil
Crystal structure of UDPX-SrUGT76G1
分子名称: UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE-XYLOPYRANOSE
著者Li, J.X, Liu, Z.F, Wang, Y, Zhang, P.
登録日2019-09-04
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1.
Plant Commun., 1, 2020
6KVK
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BU of 6kvk by Molmil
Crystal structure of UDP-Sm-SrUGT76G1
分子名称: Steviolmonoside, UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE
著者Li, J.X, Liu, Z.F, Wang, Y, Zhang, P.
登録日2019-09-04
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1.
Plant Commun., 1, 2020
3HZQ
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BU of 3hzq by Molmil
Structure of a tetrameric MscL in an expanded intermediate state
分子名称: Large-conductance mechanosensitive channel
著者Liu, Z.F, Gandhi, C.S, Rees, D.C.
登録日2009-06-24
公開日2009-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.82 Å)
主引用文献Structure of a tetrameric MscL in an expanded intermediate state.
Nature, 461, 2009
6U0D
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BU of 6u0d by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZL0590
分子名称: Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, N-[4-({(2S)-2-[(morpholin-4-yl)methyl]pyrrolidin-1-yl}sulfonyl)phenyl]-N'-[4-(trifluoromethyl)phenyl]urea
著者Leonard, P.G, Joseph, S.
登録日2019-08-14
公開日2020-08-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site
J. Med. Chem., 2022
4YVU
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BU of 4yvu by Molmil
Crystal structure of CotA native enzyme in the acid condition, PH5.6
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, GLYCEROL, ...
著者Liu, Z.C, Xie, T, Wang, G.G.
登録日2015-03-20
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of CotA laccase complexed with 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) at a novel binding site
Acta Crystallogr.,Sect.F, 72, 2016
2Y8U
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A. nidulans chitin deacetylase
分子名称: CHITIN DEACETYLASE, CHLORIDE ION, COBALT (II) ION, ...
著者Penman, G, Gay, L.M, van Aalten, D.M.F.
登録日2011-02-10
公開日2012-02-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure and function of a broad-specificity chitin deacetylase from Aspergillus nidulans FGSC A4.
Sci Rep, 7, 2017
4YVN
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BU of 4yvn by Molmil
Crystal structure of CotA laccase complexed with ABTS at a novel binding site
分子名称: 1,2-ETHANEDIOL, 3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM, COPPER (II) ION, ...
著者Liu, Z.C, Xie, T, Wang, G.G.
登録日2015-03-20
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of CotA laccase complexed with 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) at a novel binding site
Acta Crystallogr.,Sect.F, 72, 2016
7S0Y
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BU of 7s0y by Molmil
Structures of TcdB in complex with Cdc42
分子名称: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zheng, L, Rongsheng, J, Peng, C.
登録日2021-08-31
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
7S0Z
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BU of 7s0z by Molmil
Structures of TcdB in complex with R-Ras
分子名称: 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ...
著者Zheng, L, Rongsheng, J, Peng, C.
登録日2021-08-31
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
7KPT
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Crystal structure of CtdE in complex with FAD and substrate 4
分子名称: (6aR,7aS,11S,13aS)-6,6,11-trimethyl-4-(3-methylbut-2-en-1-yl)-6,6a,7,8,9,10,11,14-octahydro-5H,13H-13a,7a-(epiminomethano)quinolizino[2,3-b]carbazol-16-one, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Zhao, B, Hu, L.
登録日2020-11-12
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis of the stereoselective formation of the spirooxindole ring in the biosynthesis of citrinadins.
Nat Commun, 12, 2021

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