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7EJ0

Structure of the alpha2A-adrenergic receptor GoA signaling complex

Summary for 7EJ0
Entry DOI10.2210/pdb7ej0/pdb
EMDB information31147
DescriptorGuanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywordsalpha2a-adrenergic receptor, signaling complex, cryo-em, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains5
Total formula weight170138.04
Authors
Xu, J.,Cao, S.,Liu, Z.,Du, Y. (deposition date: 2021-04-01, release date: 2022-04-13, Last modification date: 2022-10-26)
Primary citationXu, J.,Cao, S.,Hubner, H.,Weikert, D.,Chen, G.,Lu, Q.,Yuan, D.,Gmeiner, P.,Liu, Z.,Du, Y.
Structural insights into ligand recognition, activation, and signaling of the alpha 2A adrenergic receptor.
Sci Adv, 8:eabj5347-eabj5347, 2022
Cited by
PubMed: 35245122
DOI: 10.1126/sciadv.abj5347
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

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