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4TL5
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BU of 4tl5 by Molmil
Crystal Structure of Human Transthyretin Ser85Pro Mutant
分子名称: CHLORIDE ION, SODIUM ION, Transthyretin
著者Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
登録日2014-05-28
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
6AEX
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BU of 6aex by Molmil
Crystal structure of unoccupied murine uPAR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor
著者Min, L, Huang, M.
登録日2018-08-06
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit.
Febs Lett., 593, 2019
4TJX
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BU of 4tjx by Molmil
Crystal structure of protease-associated domain of Arabidopsis VSR1 in complex with aleurain peptide
分子名称: Aleurain peptide, Vacuolar-sorting receptor 1
著者Luo, F, Fong, Y.H, Jiang, L.W, Wong, K.B.
登録日2014-05-25
公開日2014-12-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献How vacuolar sorting receptor proteins interact with their cargo proteins: crystal structures of apo and cargo-bound forms of the protease-associated domain from an Arabidopsis vacuolar sorting receptor.
Plant Cell, 26, 2014
4NXF
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BU of 4nxf by Molmil
Crystal structure of iLOV-I486(2LT) at pH 8.0
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Liu, X, Li, J.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.766 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
7WQV
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BU of 7wqv by Molmil
Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ...
著者Zha, J, Meng, L, Zhang, X, Li, D.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy.
Plos Pathog., 19, 2023
4NXG
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BU of 4nxg by Molmil
Crystal structure of iLOV-I486z(2LT) at pH 9.0
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Liu, X, Li, J.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXB
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BU of 4nxb by Molmil
Crystal structure of iLOV-I486(2LT) at pH 7.0
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Li, J, Liu, X.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.561 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NX2
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BU of 4nx2 by Molmil
Crystal structure of DCYRS complexed with DCY
分子名称: 3,5-dichloro-L-tyrosine, Tyrosine--tRNA ligase
著者Wang, J, Gong, W, Li, J, Gao, F, Li, H.
登録日2013-12-08
公開日2014-09-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
4NXE
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BU of 4nxe by Molmil
Crystal structure of iLOV-I486(2LT) at pH 6.5
分子名称: FLAVIN MONONUCLEOTIDE, Phototropin-2
著者Wang, J, Liu, X, Li, J.
登録日2013-12-09
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
5YY5
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BU of 5yy5 by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ...
著者Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L.
登録日2017-12-08
公開日2018-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
5VOS
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BU of 5vos by Molmil
VGSNKGAIIGL from Amyloid Beta determined by MicroED
分子名称: Amyloid beta A4 protein
著者Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S, Griner, S.L, Gonen, T.
登録日2017-05-03
公開日2018-01-03
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.42 Å)
主引用文献Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors.
J. Biol. Chem., 293, 2018
4XXB
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BU of 4xxb by Molmil
Crystal structure of human MDM2-RPL11
分子名称: 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ...
著者Zheng, J, Chen, Z.
登録日2015-01-30
公開日2015-08-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
4ZSV
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BU of 4zsv by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-1.0
分子名称: Uncharacterized protein
著者Lai, Y.-T, Yeates, T.O.
登録日2015-05-14
公開日2015-08-19
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
4ZSZ
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BU of 4zsz by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-3.0
分子名称: Uncharacterized Fusion Protein
著者Lai, Y.-T, Yeates, T.O.
登録日2015-05-14
公開日2015-08-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.251 Å)
主引用文献On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
5ZGD
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BU of 5zgd by Molmil
hnRNPA1 reversible amyloid core GFGGNDNFG (residues 209-217) determined by X-ray
分子名称: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
著者Gui, X, Xie, M, Zhao, M, Luo, F, He, J, Li, D, Liu, C.
登録日2018-03-08
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
5ZGL
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BU of 5zgl by Molmil
hnRNP A1 segment GGGYGGS (residues 234-240)
分子名称: 7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1
著者Xie, M, Luo, F, Gui, X, Zhao, M, He, J, Li, D, Liu, C.
登録日2018-03-09
公開日2019-04-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
5ZXV
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BU of 5zxv by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
分子名称: MERS-CoV RBD, heavy chain, light chain
著者Zhang, S, Wang, X.
登録日2018-05-21
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.482 Å)
主引用文献Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
4ZSX
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BU of 4zsx by Molmil
Structure of a fusion protein with a helix linker, 2ARH-3-3KAW-2.0
分子名称: PHOSPHATE ION, Uncharacterized Fusion Protein
著者Lai, Y.-T, Yeates, T.O.
登録日2015-05-14
公開日2015-08-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献On the predictability of the orientation of protein domains joined by a spanning alpha-helical linker.
Protein Eng.Des.Sel., 28, 2015
4RIL
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BU of 4ril by Molmil
Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction
分子名称: Alpha-synuclein
著者Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2023-09-20
実験手法ELECTRON CRYSTALLOGRAPHY (1.43 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
8JI8
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BU of 8ji8 by Molmil
Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (II) ION, ...
著者Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q.
登録日2023-05-26
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mosquitoes have evolved two types of prophenoloxidases
To Be Published
6C3G
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BU of 6c3g by Molmil
AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
分子名称: GLYCEROL, LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION
著者Saelices, L, Sawaya, M.R, Eisenberg, D.S.
登録日2018-01-09
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
5Z65
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BU of 5z65 by Molmil
Crystal structure of porcine aminopeptidase N ectodomain in functional form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Sun, Y.G, Li, R, Jiang, L.G, Qiao, S.L, Zhang, G.P.
登録日2018-01-22
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Characterization of the interaction between recombinant porcine aminopeptidase N and spike glycoprotein of porcine epidemic diarrhea virus.
Int. J. Biol. Macromol., 117, 2018
5E4K
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BU of 5e4k by Molmil
Structure of ligand binding region of uPARAP at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, C-type mannose receptor 2, ...
著者Yuan, C, Huang, M.
登録日2015-10-06
公開日2016-08-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding
Biochem.J., 473, 2016
8JIB
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BU of 8jib by Molmil
Crystal Structure of Prophenoloxidase PPO6 from Aedes aegypti
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, TK receptor
著者Zhu, X, Zhang, L, Yang, X, Bao, P, Ren, D, Han, Q.
登録日2023-05-26
公開日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Mosquitoes have evolved two types of prophenoloxidases
To Be Published
6A8G
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BU of 6a8g by Molmil
The crystal structure of muPAin-1-IG in complex with muPA-SPD at pH8.5
分子名称: PHOSPHATE ION, Urokinase-type plasminogen activator chain B, muPAin-1-IG
著者Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z.
登録日2018-07-08
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides.
J.Med.Chem., 62, 2019

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