7DZK
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![BU of 7dzk by Molmil](/molmil-images/mine/7dzk) | Fabp protein after hv | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | 登録日 | 2021-01-25 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
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7DZL
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![BU of 7dzl by Molmil](/molmil-images/mine/7dzl) | A69C-M71L mutant of Fabp protein | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | 登録日 | 2021-01-25 | 公開日 | 2022-07-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser. Nat.Chem., 14, 2022
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7FEO
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![BU of 7feo by Molmil](/molmil-images/mine/7feo) | Crystal structure of AtMBD5 MBD domain | 分子名称: | Methyl-CpG-binding domain-containing protein 5, SULFATE ION | 著者 | Zhou, M.Q, Wu, Z.B, Liu, K, Min, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2021-07-21 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs. J.Mol.Biol., 434, 2022
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7FEF
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![BU of 7fef by Molmil](/molmil-images/mine/7fef) | Crystal structure of AtMBD6 with DNA | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain-containing protein 6 | 著者 | Wu, Z.B, Liu, K, Min, J.R. | 登録日 | 2021-07-19 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs. J.Mol.Biol., 434, 2022
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7X53
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![BU of 7x53 by Molmil](/molmil-images/mine/7x53) | cytochrome P450 monooxygenase | 分子名称: | Cytochrome P450 family protein, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Yan, Y, Zheng, C. | 登録日 | 2022-03-03 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Structure of cytochrome P450 monooxygenase at 3.35 Angstroms resolution. To Be Published
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5XFJ
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9BRA
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![BU of 9bra by Molmil](/molmil-images/mine/9bra) | Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRT
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![BU of 9brt by Molmil](/molmil-images/mine/9brt) | Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRZ
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![BU of 9brz by Molmil](/molmil-images/mine/9brz) | V0-only V-ATPase and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-12 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRS
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![BU of 9brs by Molmil](/molmil-images/mine/9brs) | Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRU
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![BU of 9bru by Molmil](/molmil-images/mine/9bru) | Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRQ
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![BU of 9brq by Molmil](/molmil-images/mine/9brq) | Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRY
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![BU of 9bry by Molmil](/molmil-images/mine/9bry) | V0-only V-ATPase in synaptophysin gene knock-out mouse brain isolated synaptic vesicles | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-12 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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9BRR
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![BU of 9brr by Molmil](/molmil-images/mine/9brr) | Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles | 分子名称: | Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ... | 著者 | Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T. | 登録日 | 2024-05-11 | 公開日 | 2024-06-19 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure and topography of the synaptic V-ATPase-synaptophysin complex. Nature, 631, 2024
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6XVD
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![BU of 6xvd by Molmil](/molmil-images/mine/6xvd) | Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition | 分子名称: | Urokinase-type plasminogen activator, upain-1-W3F | 著者 | Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G. | 登録日 | 2020-01-21 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases. Biosci.Biotechnol.Biochem., 84, 2020
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6LBM
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6LBI
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6LHD
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![BU of 6lhd by Molmil](/molmil-images/mine/6lhd) | Crystal structure of p53/BCL-xL fusion complex | 分子名称: | ZINC ION, fusion protein of Bcl-2-like protein 1 and Isoform 6 of Cellular tumor antigen p53 | 著者 | Wei, H, Chen, Y. | 登録日 | 2019-12-07 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis. Nat Commun, 12, 2021
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6L8L
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![BU of 6l8l by Molmil](/molmil-images/mine/6l8l) | C-Src in complex with ibrutinib | 分子名称: | 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src | 著者 | Guo, M, Dai, S, Chen, L, Chen, Y. | 登録日 | 2019-11-06 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.888 Å) | 主引用文献 | Characterization of ibrutinib as a non-covalent inhibitor of SRC-family kinases. Bioorg.Med.Chem.Lett., 34, 2020
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8I6Q
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6LS5
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![BU of 6ls5 by Molmil](/molmil-images/mine/6ls5) | Structure of human liver FBPase complexed with covalent allosteric inhibitor | 分子名称: | 2-(ethyldisulfanyl)-1,3-benzothiazole, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | 著者 | Yunyuan, H, Rongrong, S, Yixiang, X, Shuaishuai, N, Yanliang, R, Jian, L, Jian, W. | 登録日 | 2020-01-17 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction. J.Med.Chem., 63, 2020
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5XN6
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![BU of 5xn6 by Molmil](/molmil-images/mine/5xn6) | Heterodimer crystal structure of geranylgeranyl diphosphate synthases 1 with GGPPS Recruiting Protein(OsGRP) from Oryza sativa | 分子名称: | Os02g0668100 protein, Os07g0580900 protein | 著者 | Wang, C, Zhou, F, Lu, S, Zhang, P. | 登録日 | 2017-05-18 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.598 Å) | 主引用文献 | A recruiting protein of geranylgeranyl diphosphate synthase controls metabolic flux toward chlorophyll biosynthesis in rice Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6LT0
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![BU of 6lt0 by Molmil](/molmil-images/mine/6lt0) | cryo-EM structure of C9ORF72-SMCR8-WDR41 | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | 著者 | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | 登録日 | 2020-01-21 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. Proc.Natl.Acad.Sci.USA, 117, 2020
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7D57
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![BU of 7d57 by Molmil](/molmil-images/mine/7d57) | C-Src in complex with FIIN-2 | 分子名称: | N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION | 著者 | Chen, Y.H, Qu, L.Z. | 登録日 | 2020-09-25 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors Commun Chem, 5, 2022
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9BFY
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![BU of 9bfy by Molmil](/molmil-images/mine/9bfy) | Tri-complex of Compound-12, KRAS G12C, and CypA | 分子名称: | (3R)-N-[(2S)-1-{[(1M,8R,10R,14S,21M)-22-ethyl-4-hydroxy-21-{2-[(1R)-1-methoxyethyl]pyridin-3-yl}-18,18-dimethyl-9,15-dioxo-16-oxa-10,22,28-triazapentacyclo[18.5.2.1~2,6~.1~10,14~.0~23,27~]nonacosa-1(25),2(29),3,5,20,23,26-heptaen-8-yl]amino}-3-methyl-1-oxobutan-2-yl]-N-methyl-1-propanoylpyrrolidine-3-carboxamide (non-preferred name), CHLORIDE ION, GTPase KRas, ... | 著者 | Tomlinson, A.C.A, Saldajeno-Concar, M, Knox, J.E, Yano, J.K. | 登録日 | 2024-04-18 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Tri-complex of Compound-12, KRAS G12C, and CypA To be published
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