4L1U
| Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide | 分子名称: | GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ... | 著者 | Wier, A.D, Heroux, A, VanDemark, A.P. | 登録日 | 2013-06-03 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.424 Å) | 主引用文献 | Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin. Proc.Natl.Acad.Sci.USA, 110, 2013
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1MNB
| BIV TAT PEPTIDE (RESIDUES 68-81), NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BIV TAR RNA, BIV TAT PEPTIDE | 著者 | Puglisi, J.D, Chen, L, Blanchard, S, Frankel, A.D. | 登録日 | 1996-07-25 | 公開日 | 1997-01-27 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex. Science, 270, 1995
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1N5Y
| HIV-1 Reverse Transcriptase Crosslinked to Post-Translocation AZTMP-Terminated DNA (Complex P) | 分子名称: | 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3', 5'-D(*AP*TP*GP*C*TP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ... | 著者 | Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, P, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E. | 登録日 | 2002-11-07 | 公開日 | 2003-01-28 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of HIV-1 Reverse Transcriptase with Pre-Translocation and Post-Translocation AZTMP-Terminated DNA Embo J., 21, 2002
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1N6Q
| HIV-1 Reverse Transcriptase Crosslinked to pre-translocation AZTMP-terminated DNA (complex N) | 分子名称: | 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*AP*(ATM))-3', 5'-D(*AP*T*GP*CP*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ... | 著者 | Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, I, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E. | 登録日 | 2002-11-11 | 公開日 | 2003-01-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of HIV-1 Reverse Transcriptase with Pre- and Post-translocation AZTMP-terminated DNA Embo J., 21, 2002
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4JO8
| Crystal structure of the activating Ly49H receptor in complex with m157 (G1F strain) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell lectin-like receptor 8, M157 | 著者 | Berry, R, Ng, N, Saunders, P.M, Vivian, J.P, Lin, J, Deuss, F.A, Corbett, A.J, Forbes, C.A, Widjaja, J.M, Sullivan, L.C, McAlister, A.D, Perugini, M.A, Call, M.J, Scalzo, A.A, Degli-Esposti, M.A, Coudert, J.D, Beddoe, T, Brooks, A.G, Rossjohn, J. | 登録日 | 2013-03-18 | 公開日 | 2013-05-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Targeting of a natural killer cell receptor family by a viral immunoevasin Nat.Immunol., 14, 2013
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4JX4
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1L5Z
| CRYSTAL STRUCTURE OF THE E121K SUBSTITUTION OF THE RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | 分子名称: | C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, GLYCEROL, SULFATE ION | 著者 | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | 登録日 | 2002-03-08 | 公開日 | 2002-10-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain FASEB J., 16, 2002
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1KEW
| The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with thymidine diphosphate bound | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, ... | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | 登録日 | 2001-11-17 | 公開日 | 2002-01-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Toward a structural understanding of the dehydratase mechanism. Structure, 10, 2002
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1KER
| The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-D-glucose bound | 分子名称: | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | 登録日 | 2001-11-17 | 公開日 | 2002-01-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Toward a structural understanding of the dehydratase mechanism. Structure, 10, 2002
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1P45
| Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | 著者 | Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B.N, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-04-21 | 公開日 | 2003-09-16 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. J.Biol.Chem., 278, 2003
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4M5W
| Crystal structure of the USP7/HAUSP catalytic domain | 分子名称: | BROMIDE ION, Ubiquitin carboxyl-terminal hydrolase 7 | 著者 | Molland, K.L, Mesecar, A.D, Zhou, Q. | 登録日 | 2013-08-08 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | 主引用文献 | A 2.2 angstrom resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding. Acta Crystallogr F Struct Biol Commun, 70, 2014
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6DLU
| Cryo-EM of the GMPPCP-bound human dynamin-1 polymer assembled on the membrane in the constricted state | 分子名称: | Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | 著者 | Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. | 登録日 | 2018-06-02 | 公開日 | 2018-08-01 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
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1BH5
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3OWX
| X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | 分子名称: | 2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Pegan, S.D, Sturdy, M, Ferry, G, Delagrange, P, Boutin, J.A, Mesecar, A.D. | 登録日 | 2010-09-20 | 公開日 | 2011-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors. Protein Sci., 20, 2011
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6E9L
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6E6O
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8QAQ
| Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. Conformation 1 of omphalotin A in apolar solvents. | 分子名称: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | 著者 | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | 登録日 | 2023-08-23 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8Q7J
| Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability | 分子名称: | CYCLOSPORIN A | 著者 | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | 登録日 | 2023-08-16 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QAS
| Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | 分子名称: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | 著者 | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | 登録日 | 2023-08-23 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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6E9W
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8QBP
| Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | 分子名称: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | 著者 | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | 登録日 | 2023-08-25 | 公開日 | 2023-12-13 | 最終更新日 | 2024-01-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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3OX1
| X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, N-{2-[7-(methylsulfamoyl)naphthalen-1-yl]ethyl}acetamide, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | 著者 | Pegan, S.D, Sturdy, M, Ferry, G, Delagrange, P, Boutin, J.A, Mesecar, A.D. | 登録日 | 2010-09-21 | 公開日 | 2011-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors. Protein Sci., 20, 2011
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6ED6
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8SLT
| Crystal structure of human STEP (PTPN5) at physiological temperature (310 K) and ambient pressure (0.1 MPa) | 分子名称: | SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | 登録日 | 2023-04-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase. Biorxiv, 2023
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8SLU
| Crystal structure of human STEP (PTPN5) at cryogenic temperature (100 K) and high pressure (205 MPa) | 分子名称: | GLYCEROL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 5 | 著者 | Ebrahim, A, Guerrero, L, Riley, B.T, Kim, M, Huang, Q, Finke, A.D, Keedy, D.A. | 登録日 | 2023-04-24 | 公開日 | 2023-06-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase. Biorxiv, 2023
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