8J60
| Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery | 分子名称: | LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3 | 著者 | Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L. | 登録日 | 2023-04-24 | 公開日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
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7CFM
| Cryo-EM structure of the P395-bound GPBAR-Gs complex | 分子名称: | 2-(ethylamino)-6-[3-(4-propan-2-ylphenyl)propanoyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-4-carboxamide, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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7CFN
| Cryo-EM structure of the INT-777-bound GPBAR-Gs complex | 分子名称: | (2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-10,13-dimethyl-3,7,12-tris(oxidanyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-pentanoic acid, CHOLESTEROL, G-protein coupled bile acid receptor 1, ... | 著者 | Yang, F, Mao, C, Guo, L, Lin, J, Ming, Q, Xiao, P, Wu, X, Shen, Q, Guo, S, Shen, D, Lu, R, Zhang, L, Huang, S, Ping, Y, Zhang, C, Ma, C, Zhang, K, Liang, X, Shen, Y, Nan, F, Yi, F, Luca, V, Zhou, J, Jiang, C, Sun, J, Xie, X, Yu, X, Zhang, Y. | 登録日 | 2020-06-27 | 公開日 | 2020-09-09 | 最終更新日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of GPBAR activation and bile acid recognition. Nature, 587, 2020
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5EWP
| ARO (armadillo repeats only protein) from Plasmodium falciparum | 分子名称: | ARO (armadillo repeats only protein) | 著者 | Brown, C, Zhang, K, Emery, J, Prusty, D, Wetzel, J, Heincke, D, Gilberger, T, Junop, M. | 登録日 | 2015-11-20 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | ARO (armadillo repeats only protein) from Plasmodium falciparum To Be Published
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5HSI
| Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | 分子名称: | MAGNESIUM ION, Putative decarboxylase | 著者 | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | 登録日 | 2016-01-25 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | 主引用文献 | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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5HSJ
| Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase | 著者 | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | 登録日 | 2016-01-25 | 公開日 | 2016-09-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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7F02
| Cytochrome c-type biogenesis protein CcmABCD from E. coli | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7F03
| Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7F04
| Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... | 著者 | Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. | 登録日 | 2021-06-03 | 公開日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7YTY
| Mouse SVCT1 in an apo state | 分子名称: | Solute carrier family 23 member 1 | 著者 | She, J, Wang, M, He, J, Zhang, K, Li, S. | 登録日 | 2022-08-16 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter. Nat Commun, 14, 2023
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7YTW
| Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter | 分子名称: | ASCORBIC ACID, SODIUM ION, Solute carrier family 23 member 1 | 著者 | She, J, Wang, M, He, J, Zhang, K, Li, S. | 登録日 | 2022-08-16 | 公開日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter. Nat Commun, 14, 2023
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7YPK
| Close-ring hexamer of the substrate-bound Lon protease with an S678A mutation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease, alpha-S1-casein | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPH
| Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPJ
| Spiral pentamer of the substrate-free Lon protease with a S678A mutation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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7YPI
| Spiral hexamer of the substrate-free Lon protease with a Y224S mutation | 分子名称: | Lon protease, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Lee, S.H, Ho, M.R, Wang, C.H, Zhang, K, Chang, C.I. | 登録日 | 2022-08-03 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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6LS4
| A novel anti-tumor agent S-40 in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | 著者 | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | 登録日 | 2020-01-17 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity. Cancer Lett., 495, 2020
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4MBQ
| TPR3 of FimV from P. aeruginosa (PAO1) | 分子名称: | Motility protein FimV | 著者 | Nguyen, Y, Zhang, K, Daniel-Ivad, M, Robinson, H, Wolfram, F, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L. | 登録日 | 2013-08-19 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | 主引用文献 | Crystal structure of TPR2 from FimV To be Published
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3T9K
| Crystal Structure of ACAP1 C-portion mutant S554D fused with integrin beta1 peptide | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1,Peptide from Integrin beta-1, SULFATE ION, ... | 著者 | Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. | 登録日 | 2011-08-03 | 公開日 | 2012-07-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
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4MAL
| TPR3 of FimV from P. aeruginosa (PAO1) | 分子名称: | Motility protein FimV | 著者 | Nguyen, Y, Zhang, K, Daniel-Ivad, M, Sugiman-Marangos, S.N, Junop, M.S, Burrows, L.L, Howell, P.L. | 登録日 | 2013-08-16 | 公開日 | 2014-08-20 | 最終更新日 | 2016-02-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of TPR2 from FimV To be Published
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8J72
| Crystal structure of mammalian Trim71 in complex with lncRNA Trincr1 | 分子名称: | E3 ubiquitin-protein ligase TRIM71, lncRNA Trincr1 | 著者 | Shi, F.D, Zhang, K, Che, S.Y, Zhi, S.X, Yang, N. | 登録日 | 2023-04-27 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | 主引用文献 | Molecular mechanism governing RNA-binding property of mammalian TRIM71 protein. Sci Bull (Beijing), 69, 2024
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3U9G
| Crystal structure of the Zinc finger antiviral protein | 分子名称: | ZINC ION, Zinc finger CCCH-type antiviral protein 1 | 著者 | Chen, S, Xu, Y, Zhang, K, Wang, X, Sun, J, Gao, G, Liu, Y. | 登録日 | 2011-10-18 | 公開日 | 2012-03-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA. Nat.Struct.Mol.Biol., 19, 2012
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8K3Y
| The "5+1" heteromeric structure of Lon protease consisting of a spiral pentamer with Y224S mutation and an N-terminal-truncated monomeric E613K mutant | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | 著者 | Li, S, Hsieh, K.Y, Kuo, C.I, Zhang, K, Chang, C.I. | 登録日 | 2023-07-17 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine. Nat Commun, 14, 2023
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4NPH
| Crystal structure of SsaN from Salmonella enterica | 分子名称: | Probable secretion system apparatus ATP synthase SsaN | 著者 | Sugiman-Marangos, S.N, Zhang, K, Cooper, C.A, Coombes, B.K, Junop, M.S. | 登録日 | 2013-11-21 | 公開日 | 2014-07-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of SsaN from Salmonella enterica J.Biol.Chem., 2014
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4OIY
| Crystal structure of Sec7p catalytic domain | 分子名称: | MAGNESIUM ION, Protein transport protein SEC7 | 著者 | Qiu, B, Zhang, K, Sun, F. | 登録日 | 2014-01-20 | 公開日 | 2014-07-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation Biochem.Biophys.Res.Commun., 446, 2014
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7XDT
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