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8K5A

The cryo-EM map of open TIEA-TEC complex

Summary for 8K5A
Entry DOI10.2210/pdb8k5a/pdb
EMDB information36899
DescriptorDNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywordsbacteriophage t4, rna polymerase, transcription, inhibitor, elongation accelerator, complex, transcription/dna/rna, transcription-dna-rna complex
Biological sourceEscherichia coli K-12
More
Total number of polymer chains9
Total formula weight397071.31
Authors
Zhang, K.N.,Liu, Y.,Chen, M.,Wang, Y.,Lin, W.,Li, M.,Zhang, X.,Gao, Y.,Gong, Q.,Chen, H.,Steve, M.,Li, S.,Zhang, K.,Liu, B. (deposition date: 2023-07-21, release date: 2024-07-24, Last modification date: 2024-10-23)
Primary citationZhang, K.N.,Liu, Y.,Chen, M.,Wang, Y.,Lin, W.,Li, M.,Zhang, X.,Gao, Y.,Gong, Q.,Chen, H.,Steve, M.,Li, S.,Zhang, K.,Liu, B.
TIEA inhibits sigma70-dependent transcriptions, accelerates elongation speed and elevates transcription error
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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PDB entries from 2024-11-06

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