8HK1
 
 | | The cryo-EM structure of human pre-17S U2 snRNP | | 分子名称: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2022-11-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
Nat Commun, 14, 2023
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5NWT
 | | Crystal Structure of Escherichia coli RNA polymerase - Sigma54 Holoenzyme complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhang, X, Buck, M, Darbari, V.C, Yang, Y, Zhang, N, Lu, D, Glyde, R, Wang, Y, Winkelman, J, Gourse, R.L, Murakami, K.S. | | 登録日 | 2017-05-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase-Sigma54 reveal new and conserved regulatory strategies.
Science, 349, 2015
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2R25
 | | Complex of YPD1 and SLN1-R1 with bound Mg2+ and BeF3- | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Osmosensing histidine protein kinase SLN1, ... | | 著者 | Copeland, D.M, Zhao, X, Soares, A.S, West, A.H. | | 登録日 | 2007-08-24 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a complex between the phosphorelay protein YPD1 and
the response regulator domain of SLN1 bound to a phosphoryl analog
J.Mol.Biol., 375, 2008
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1J04
 | | Structural mechanism of enzyme mistargeting in hereditary kidney stone disease in vitro | | 分子名称: | (AMINOOXY)ACETIC ACID, GLYCEROL, alanine--glyoxylate aminotransferase | | 著者 | Zhang, X, Djordjevic, S, Bartlam, M, Ye, S, Rao, Z, Danpure, C.J. | | 登録日 | 2002-10-30 | | 公開日 | 2003-11-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.
Acta Crystallogr.,Sect.F, 66, 2010
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8INB
 | | Cryo-EM structure of Cas12j-SF05-crRNA-dsDNA complex | | 分子名称: | Cas12j-SF05, NTS-DNA, TS-DNA, ... | | 著者 | Zhang, X, Duan, Z.Q, Zhu, J.K. | | 登録日 | 2023-03-09 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05.
Cell Discov, 9, 2023
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5TEB
 | | Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1 | | 分子名称: | Recognition of Peronospora parasitica 1 | | 著者 | Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B. | | 登録日 | 2016-09-20 | | 公開日 | 2017-02-01 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.796 Å) | | 主引用文献 | Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7DY9
 | | Thermotoga maritima ferritin mutant-FLAL | | 分子名称: | Ferritin | | 著者 | Zhao, G, Zhang, X. | | 登録日 | 2021-01-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
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7DYB
 | | Thermotoga maritima ferritin mutant-FLAL-L | | 分子名称: | FE (III) ION, Ferritin | | 著者 | Zhao, G, Zhang, X. | | 登録日 | 2021-01-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.779 Å) | | 主引用文献 | Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
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5T7Q
 | | TIRAP phosphoinositide-binding motif | | 分子名称: | Toll/interleukin-1 receptor domain-containing adapter protein | | 著者 | Capelluto, D.G.S, Ellena, J.F, Armstrong, G, Zhao, X, Xiao, S. | | 登録日 | 2016-09-05 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif.
Sci Rep, 7, 2017
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7YSK
 | | Crystal structure of D-Cysteine desulfhydrase from Pectobacterium atrosepticum | | 分子名称: | D-Cysteine desulfhydrase | | 著者 | Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J. | | 登録日 | 2022-08-12 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum
Tetrahedron, 2022
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7YSL
 | | Crystal structure of D-Cysteine desulfhydrase with a trapped PLP-pyruvate geminal diamine | | 分子名称: | 1,2-ETHANEDIOL, D-Cysteine desulfhydrase, FORMIC ACID | | 著者 | Zhang, X, Wang, L, Xu, X, Xing, X, Zhou, J. | | 登録日 | 2022-08-12 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Characterization and structural basis of D-cysteine desulfhydrase from Pectobacterium atrosepticum
Tetrahedron, 2022
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6LCY
 | | Crystal structure of Synaptotagmin-7 C2B in complex with IP6 | | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-7 | | 著者 | Zhang, Y, Zhang, X, Rao, F, Wang, C. | | 登録日 | 2019-11-20 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis.
Nat Metab, 3, 2021
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4C51
 | | Crystal Structure of the Catalase-Peroxidase (KatG) R418L mutant from Mycobacterium Tuberculosis | | 分子名称: | CATALASE-PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, alpha-D-glucopyranose | | 著者 | Hersleth, H.-P, Zhao, X, Magliozzo, R.S, Andersson, K.K. | | 登録日 | 2013-09-10 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49, 2013
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5GQH
 | | Cryo-EM structure of PaeCas3-AcrF3 complex | | 分子名称: | CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3 | | 著者 | Zhang, X, Ma, J, Wang, Y, Wang, J. | | 登録日 | 2016-08-07 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
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8XJK
 | | Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex | | 分子名称: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | | 登録日 | 2023-12-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
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8XJM
 | | Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex | | 分子名称: | Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ... | | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | | 登録日 | 2023-12-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
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8XJO
 | | U46619 bound Thromboxane A2 receptor-Gq Protein Complex | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | | 登録日 | 2023-12-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
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8XJN
 | | Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex | | 分子名称: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | | 登録日 | 2023-12-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
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8XJL
 | | PGF2-alpha bound Prostaglandin F2-alpha receptor-Gq Protein Complex | | 分子名称: | (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | | 著者 | Zhang, X, Li, X, Liu, G, Gong, W. | | 登録日 | 2023-12-21 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of the prostanoid receptors.
Cell Rep, 43, 2024
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4C50
 | | Crystal Structure of the Catalase-Peroxidase (KatG) D137S mutant from Mycobacterium Tuberculosis | | 分子名称: | ACETATE ION, CATALASE-PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Hersleth, H.-P, Zhao, X, Magliozzo, R.S, Andersson, K.K. | | 登録日 | 2013-09-10 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Access Channel Residues Ser315 and Asp137 in Mycobacterium Tuberculosis Catalase-Peroxidase (Katg) Control Peroxidatic Activation of the Pro-Drug Isoniazid.
Chem.Commun.(Camb.), 49, 2013
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1RHP
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3O5X
 | | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | | 分子名称: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | | 登録日 | 2010-07-28 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
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4O9F
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3P2D
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4OA7
 | | Crystal structure of Tankyrase1 in complex with IWR1 | | 分子名称: | 4-[(3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION | | 著者 | Zhang, X, He, H. | | 登録日 | 2014-01-03 | | 公開日 | 2015-01-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
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