TIRAP phosphoinositide-binding motif

Summary for 5T7Q

DescriptorToll/interleukin-1 receptor domain-containing adapter protein (1 entity in total)
Functional Keywordstirap, phosphoinositide, phosphorylation, phosphoinositide-binding motif; structure, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight2550.2
Capelluto, D.G.S.,Ellena, J.F.,Armstrong, G.,Zhao, X.,Xiao, S. (deposition date: 2016-09-05, release date: 2017-03-08, Last modification date: 2018-08-29)
Primary citation
Zhao, X.,Xiong, W.,Xiao, S.,Tang, T.X.,Ellena, J.F.,Armstrong, G.S.,Finkielstein, C.V.,Capelluto, D.G.
Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif.
Sci Rep, 7:43043-43043, 2017
PubMed: 28225045 (PDB entries with the same primary citation)
DOI: 10.1038/srep43043
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers000MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

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