8J03
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6O8L
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8J05
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2E9D
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![BU of 2e9d by Molmil](/molmil-images/mine/2e9d) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-676 | 分子名称: | Undecaprenyl pyrophosphate synthetase, [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID) | 著者 | Guo, R.T, Cao, R, Ko, T.P, Liang, P.H, Oldfield, E, Wang, A.H.J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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8J04
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![BU of 8j04 by Molmil](/molmil-images/mine/8j04) | Human KCNQ2-CaM-HN37 complex in the presence of PIP2 | 分子名称: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, methyl N-[4-[(4-fluorophenyl)methyl-prop-2-ynyl-amino]-2,6-dimethyl-phenyl]carbamate | 著者 | Ma, D, Li, X, Guo, J. | 登録日 | 2023-04-09 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Ligand activation mechanisms of human KCNQ2 channel. Nat Commun, 14, 2023
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2E98
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![BU of 2e98 by Molmil](/molmil-images/mine/2e98) | E. coli undecaprenyl pyrophosphate synthase in complex with BPH-629 | 分子名称: | Undecaprenyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID | 著者 | Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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3CCN
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![BU of 3ccn by Molmil](/molmil-images/mine/3ccn) | X-ray structure of c-Met with triazolopyridazine inhibitor. | 分子名称: | 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol, Hepatocyte growth factor receptor | 著者 | Abrecht, B.K, Harmange, J.-C, Bauer, D, Dussault, I, long, A, Bellon, S.F. | 登録日 | 2008-02-26 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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8F5F
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![BU of 8f5f by Molmil](/molmil-images/mine/8f5f) | human branched chain ketoacid dehydrogenase kinase in complex with inhibitors | 分子名称: | (2P)-2-[(4P)-4-{6-[(1-ethylcyclopropyl)methoxy]pyridin-3-yl}-1,3-thiazol-2-yl]benzoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Liu, S, Roth Flach, R, Bollinger, E, Filipski, K. | 登録日 | 2022-11-14 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.149 Å) | 主引用文献 | Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels. Nat Commun, 14, 2023
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8F5J
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![BU of 8f5j by Molmil](/molmil-images/mine/8f5j) | human branched chain ketoacid dehydrogenase kinase in complex with inhibitors | 分子名称: | 3-chloro-5-fluorothieno[3,2-b]thiophene-2-carboxylic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Liu, S, Roth Flach, R, Bollinger, E, Filipski, K. | 登録日 | 2022-11-14 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | 主引用文献 | Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels. Nat Commun, 14, 2023
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8F5S
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![BU of 8f5s by Molmil](/molmil-images/mine/8f5s) | human branched chain ketoacid dehydrogenase kinase in complex with inhibitors | 分子名称: | (2M)-2-[2-(4-methylphenyl)-1,3-thiazol-4-yl]benzoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Liu, S, Roth Flach, R, Bollinger, E, Filipski, K. | 登録日 | 2022-11-15 | 公開日 | 2023-07-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.793 Å) | 主引用文献 | Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels. Nat Commun, 14, 2023
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6BX3
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![BU of 6bx3 by Molmil](/molmil-images/mine/6bx3) | Structure of histone H3k4 methyltransferase | 分子名称: | COMPASS component BRE2, COMPASS component SDC1, COMPASS component SPP1, ... | 著者 | Skiniotis, G, Qu, Q.H. | 登録日 | 2017-12-16 | 公開日 | 2018-09-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex. Cell, 174, 2018
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4H8E
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2E8V
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![BU of 2e8v by Molmil](/molmil-images/mine/2e8v) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21) | 分子名称: | GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase | 著者 | Chen, C.K.-M, Guo, R.T, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-23 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E92
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![BU of 2e92 by Molmil](/molmil-images/mine/2e92) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-261 | 分子名称: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Ko, T.P, Cao, R, Jeng, W.Y, Chen, C.K.-M, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E8U
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![BU of 2e8u by Molmil](/molmil-images/mine/2e8u) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21) | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION | 著者 | Guo, R.T, Chen, C.K.-M, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-23 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E91
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![BU of 2e91 by Molmil](/molmil-images/mine/2e91) | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91 | 分子名称: | Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, ZOLEDRONIC ACID | 著者 | Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J. | 登録日 | 2007-01-24 | 公開日 | 2007-06-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases Proc.Natl.Acad.Sci.Usa, 104, 2007
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6O8O
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![BU of 6o8o by Molmil](/molmil-images/mine/6o8o) | Crystal Structure of C9S disulfide state of Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus. | 分子名称: | CHLORIDE ION, SULFATE ION, Transcriptional regulator, ... | 著者 | Capdevila, D.A, Gonzalez-Gutierrez, G, Giedroc, D.P. | 登録日 | 2019-03-11 | 公開日 | 2020-04-01 | 最終更新日 | 2020-12-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for persulfide-sensing specificity in a transcriptional regulator. Nat.Chem.Biol., 17, 2021
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4H38
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5H6I
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![BU of 5h6i by Molmil](/molmil-images/mine/5h6i) | Crystal Structure of GBS CAMP Factor | 分子名称: | CHLORIDE ION, Protein B, SULFATE ION | 著者 | Jin, T.C, Brefo-Mensah, E.K. | 登録日 | 2016-11-13 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of theStreptococcus agalactiaeCAMP factor provides insights into its membrane-permeabilizing activity. J.Biol.Chem., 293, 2018
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4H3C
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6O8K
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![BU of 6o8k by Molmil](/molmil-images/mine/6o8k) | Crystal Structure of apo and reduced Sulfide-responsive transcriptional repressor (SqrR) from Rhodobacter capsulatus. | 分子名称: | GLYCEROL, SULFATE ION, Transcriptional regulator, ... | 著者 | Capdevila, D.A, Gonzalez-Gutierrez, G, Giedroc, D.P. | 登録日 | 2019-03-11 | 公開日 | 2020-04-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural basis for persulfide-sensing specificity in a transcriptional regulator. Nat.Chem.Biol., 17, 2021
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4MXK
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![BU of 4mxk by Molmil](/molmil-images/mine/4mxk) | X-ray structure of Fe(II)-ZnPIXFeBMb1 | 分子名称: | FE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING ZN | 著者 | Chakraborty, S, Lu, Y, Petrik, I. | 登録日 | 2013-09-26 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Spectroscopic and computational study of a nonheme iron nitrosyl center in a biosynthetic model of nitric oxide reductase. Angew.Chem.Int.Ed.Engl., 53, 2014
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1B9E
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![BU of 1b9e by Molmil](/molmil-images/mine/1b9e) | HUMAN INSULIN MUTANT SERB9GLU | 分子名称: | PROTEIN (INSULIN) | 著者 | Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M. | 登録日 | 1998-11-12 | 公開日 | 1999-11-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu). Acta Crystallogr.,Sect.D, 55, 1999
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3CD8
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![BU of 3cd8 by Molmil](/molmil-images/mine/3cd8) | X-ray Structure of c-Met with triazolopyridazine Inhibitor. | 分子名称: | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline, Hepatocyte growth factor receptor | 著者 | Bellon, S.F, Albrecht, B.K, Harmange, J.-C, Bauer, D, Choquette, D, Dussault, I. | 登録日 | 2008-02-26 | 公開日 | 2008-04-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J.Med.Chem., 51, 2008
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4P6G
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