6IZG
 
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7E9Q
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7E9O
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7KSR
 | | PRC2:EZH1_A from a dimeric PRC2 bound to a nucleosome | | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | | 著者 | Grau, D.J, Armache, K.J. | | 登録日 | 2020-11-24 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Nat Commun, 12, 2021
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7KSO
 | | Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2 | | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | | 著者 | Grau, D.J, Armache, K.J. | | 登録日 | 2020-11-23 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Nat Commun, 12, 2021
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8JAR
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7E9P
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8JAL
 | | Structure of CRL2APPBP2 bound with RxxGP degron (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-06 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAQ
 | | Structure of CRL2APPBP2 bound with RxxGP degron (tetramer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-06 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAS
 | | Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAU
 | | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (dimer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, Elongin-B, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8JAV
 | | Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) | | 分子名称: | Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Zhao, S, Zhang, K, Xu, C. | | 登録日 | 2023-05-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7E9N
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7ENF
 | | Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab30, ... | | 著者 | Wang, X.F, Zhu, Y.Q. | | 登録日 | 2021-04-16 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
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7ENG
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7KTP
 | | PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome | | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | | 著者 | Grau, D.J, Armache, K.J. | | 登録日 | 2020-11-24 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Nat Commun, 12, 2021
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8IX3
 | | Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement) | | 分子名称: | BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11 | | 著者 | Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S. | | 登録日 | 2023-03-31 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
J.Virol., 97, 2023
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5YJ8
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3FH7
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7T4V
 | | Crystal Structure of cGMP-dependent Protein Kinase | | 分子名称: | 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-methylbenzoic acid, CHLORIDE ION, cGMP-dependent protein kinase 1 | | 著者 | Zebisch, M, Silvestre, L, Fischmann, T.O. | | 登録日 | 2021-12-10 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
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7T4W
 | | Crystal Structure of cGMP-dependent Protein Kinase | | 分子名称: | (2R)-2-({(2S,3S)-1-[(1H-benzimidazol-2-yl)methyl]-2-phenylpiperidin-3-yl}oxy)-2-(3,5-dichlorophenyl)ethan-1-ol, CHLORIDE ION, cGMP-dependent protein kinase 1 | | 著者 | Zebisch, M, Silvestre, L, Fischmann, T.O. | | 登録日 | 2021-12-10 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
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3FH5
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7T4T
 | | Crystal Structure of cGMP-dependent Protein Kinase | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Zebisch, M, Silvestre, L, Fischmann, T.O. | | 登録日 | 2021-12-10 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
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7T4U
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3FH8
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