7T4T

Crystal Structure of cGMP-dependent Protein Kinase

Summary for 7T4T

• Entry DOI: 10.2210/pdb7t4t/pdb
• Descriptor: cGMP-dependent protein kinase 1, CYCLIC GUANOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: cyclic nucleotide binding domains, cyclic nucleotide protein kinase, transferase, pkg, cgmp-dependent protein kinase, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 108280.63

Authors

Zebisch, M.,Silvestre, L.,Fischmann, T.O. (deposition date: 2021-12-10, release date: 2023-06-14, Last modification date: 2024-10-23)

• Primary citation: Metwally, E.,Mak, V.,Sylvestre, H.L.,McEwan, P.,Baker, J.J.,Rose, Y.,Patel, A.,Lim, Y.-H.,Healy, D.,Hanisak, J.,Ermakov, G.,Beaumont, M.,Cheng, A.C.,Greshock, T.,Fischmann, T.O.; Selective small molecule activation of PKG1alpha: structure and function; Commun Biol, 2023

Experimental method

X-RAY DIFFRACTION (2.08 Å)