7Y4F
 
 | | bacterial DPP4 | | 分子名称: | Dipeptidyl peptidase IV | | 著者 | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | | 登録日 | 2022-06-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.918 Å) | | 主引用文献 | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Science, 381, 2023
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7Y4G
 | | sit-bound btDPP4 | | 分子名称: | (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-A MINE, btDPP4 | | 著者 | Hang, J, Jiang, C, Wang, K, Zhang, Z, Guo, F, Liu, J, Wang, G, Lei, X, Gonzalez, F, Qiao, J. | | 登録日 | 2022-06-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target.
Science, 381, 2023
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8W6A
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8W6B
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7YHS
 | | Structure of Csy-AcrIF4-dsDNA | | 分子名称: | AcrIF4, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | | 著者 | Feng, Y, Zhang, L.X. | | 登録日 | 2022-07-14 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage.
J.Biol.Chem., 298, 2022
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6TYF
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6TYG
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6U3I
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3OME
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6ILM
 | | Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 | | 分子名称: | Beta-2-microglobulin, Capsid protein VP1, Capsid protein VP2, ... | | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | | 登録日 | 2018-10-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
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3PA4
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7Y6I
 | | Cryo-EM structure of human sodium-chloride cotransporter | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q. | | 登録日 | 2022-06-20 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC.
Sci Adv, 8, 2022
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3P4T
 | | Crystal structure of a putative acyl-CoA dehydrogenase from Mycobacterium smegmatis | | 分子名称: | 1,2-ETHANEDIOL, Putative acyl-CoA dehydrogenase, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(4aS,10aR)-7,8-dimethyl-2,4-dioxo-1,3,4,4a,5,10a-hexahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2010-10-07 | | 公開日 | 2010-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
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6AH3
 | | Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate | | 分子名称: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, ... | | 著者 | Lan, P, Tan, M, Wu, J, Lei, M. | | 登録日 | 2018-08-16 | | 公開日 | 2018-10-17 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
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6ILP
 | | Cryo-EM structure of full Echovirus 6 particle at PH 7.4 | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | | 登録日 | 2018-10-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
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3P0T
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3PA5
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6ILN
 | | Cryo-EM structure of full Echovirus 6 particle at PH 5.5 | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Gao, G.F, Liu, S, Zhao, X, Peng, R. | | 登録日 | 2018-10-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
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6AGB
 | | Cryo-EM structure of yeast Ribonuclease P | | 分子名称: | RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ... | | 著者 | Lan, P, Tan, M, Wu, J, Lei, M. | | 登録日 | 2018-08-10 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
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3Q1T
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6AS7
 | | CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ... | | 著者 | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | | 登録日 | 2017-08-23 | | 公開日 | 2018-03-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Activity and fidelity of human DNA polymerase alpha depend on primer structure.
J. Biol. Chem., 293, 2018
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3PPI
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7YUB
 | | S1P-bound human SPNS2 | | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, NbFab-H-chain, NbFab-L-chain, ... | | 著者 | He, Y, Duan, Y. | | 登録日 | 2022-08-17 | | 公開日 | 2023-09-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural basis of Sphingosine-1-phosphate transport via human SPNS2.
Cell Res., 34, 2024
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3PK0
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7KMG
 | | LY-CoV555 neutralizing antibody against SARS-CoV-2 | | 分子名称: | GLYCEROL, LY-CoV555 Fab heavy chain, LY-CoV555 Fab light chain, ... | | 著者 | Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. | | 登録日 | 2020-11-02 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med, 13, 2021
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