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4XN4
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BU of 4xn4 by Molmil
Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine
分子名称: Aminopeptidase N, GLYCEROL, MALONATE ION, ...
著者Addlagatta, A, Gumpena, R.
登録日2015-01-15
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine
To Be Published
1UG9
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BU of 1ug9 by Molmil
Crystal Structure of Glucodextranase from Arthrobacter globiformis I42
分子名称: CALCIUM ION, GLYCEROL, glucodextranase
著者Mizuno, M, Tonozuka, T, Suzuki, S, Uotsu-Tomita, R, Ohtaki, A, Kamitori, S, Nishikawa, A, Sakano, Y.
登録日2003-06-16
公開日2003-12-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into substrate specificity and function of glucodextranase
J.Biol.Chem., 279, 2004
6I5I
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BU of 6i5i by Molmil
Crystal structure of CLK1 in complexed with furo[3,2-b]pyridine compound 12h
分子名称: 1,2-ETHANEDIOL, 5-(1-methylpyrazol-4-yl)-3-[1-(phenylmethyl)pyrazol-4-yl]furo[3,2-b]pyridine, Dual specificity protein kinase CLK1
著者Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Paruch, K, Knapp, S, Structural Genomics Consortium (SGC)
登録日2018-11-13
公開日2019-01-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
Angew. Chem. Int. Ed. Engl., 58, 2019
4XN7
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BU of 4xn7 by Molmil
Crystal Structure of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid
分子名称: Aminopeptidase N, DIAMINOPROPANOIC ACID, GLYCEROL, ...
著者Addlagatta, A, Gumpena, R.
登録日2015-01-15
公開日2016-03-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal Structure of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid
To Be Published
6I5S
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BU of 6i5s by Molmil
AH, Bottromycin amidohydrolase
分子名称: CHLORIDE ION, GLYCEROL, ZINC ION, ...
著者Koehnke, J, Sikandar, A.
登録日2018-11-14
公開日2019-09-25
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Thiazoline-Specific Amidohydrolase PurAH Is the Gatekeeper of Bottromycin Biosynthesis.
J.Am.Chem.Soc., 141, 2019
2W99
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BU of 2w99 by Molmil
Crystal Structure of CDK4 in complex with a D-type cyclin
分子名称: CELL DIVISION PROTEIN KINASE 4, G1/S-SPECIFIC CYCLIN-D1
著者Day, P.J, Cleasby, A, Tickle, I.J, Reilly, M.O, Coyle, J.E, Holding, F.P, McMenamin, R.L, Yon, J, Chopra, R, Lengauer, C, Jhoti, H.
登録日2009-01-22
公開日2009-03-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Cdk4 in Complex with a D-Type Cyclin.
Proc.Natl.Acad.Sci.USA, 106, 2009
4XP1
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BU of 4xp1 by Molmil
X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gouaux, E, Penmatsa, A, Wang, K.
登録日2015-01-16
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
4XPG
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BU of 4xpg by Molmil
X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428
分子名称: CHLORIDE ION, CHOLESTEROL, Dopamine transporter, ...
著者Penmatsa, A, Wang, K.H, Gouaux, E.
登録日2015-01-16
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Neurotransmitter and psychostimulant recognition by the dopamine transporter.
Nature, 521, 2015
1U0X
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BU of 1u0x by Molmil
Crystal structure of nitrophorin 4 under pressure of xenon (200 psi)
分子名称: AMMONIA, Nitrophorin 4, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Nienhaus, K, Maes, E.M, Weichsel, A, Montfort, W.R, Nienhaus, G.U.
登録日2004-07-14
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural dynamics controls nitric oxide affinity in nitrophorin 4
J.Biol.Chem., 279, 2004
4XQ0
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BU of 4xq0 by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to beryllium fluoride
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAETHYLENE GLYCOL
著者Ghosh, A, Lima, C.D.
登録日2015-01-18
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
6B0S
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BU of 6b0s by Molmil
Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody
分子名称: 1710 antibody, heavy chain, light chain, ...
著者Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P.
登録日2017-09-15
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
4XR9
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BU of 4xr9 by Molmil
Crystal structure of CalS8 from Micromonospora echinospora cocrystallized with NAD and TDP-glucose
分子名称: CalS8, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-01-20
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of CalS8 from Micromonospora echinospora
To Be Published
4MHR
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BU of 4mhr by Molmil
Crystal structure of EctD from S. alaskensis in its apoform
分子名称: Ectoine hydroxylase
著者Widderich, N, Hoeppner, A, Pittelkow, M, Heider, J, Smits, S.H, Bremer, E.
登録日2013-08-30
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the ectoine hydroxylase, a snapshot of the active site.
J.Biol.Chem., 289, 2014
4XW0
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BU of 4xw0 by Molmil
Crystal structure of (GCCU(G-LNA)CCUGC)2 duplex
分子名称: RNA (5'-R(*GP*CP*CP*UP*(LCG)P*CP*CP*UP*GP*C)-3'), SULFATE ION
著者Kiliszek, A, Banaszak, K, Rypniewski, W.
登録日2015-01-28
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Watson-Crick-like pairs in CCUG repeats: evidence for tautomeric shifts or protonation.
Rna, 22, 2016
4XCR
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BU of 4xcr by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A
分子名称: Superoxide dismutase [Cu-Zn]
著者Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M.
登録日2014-12-18
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.602 Å)
主引用文献Thermodynamics of protein destabilization in live cells.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
4XXI
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BU of 4xxi by Molmil
Crystal structure of the Bilin-binding domain of phycobilisome core-membrane linker ApcE
分子名称: PHYCOCYANOBILIN, Phycobiliprotein ApcE
著者Tang, K, Ding, W.-L, Hoppner, A, Gartner, W, Zhao, K.-H.
登録日2015-01-30
公開日2015-12-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The terminal phycobilisome emitter, LCM: A light-harvesting pigment with a phytochrome chromophore
Proc.Natl.Acad.Sci.USA, 112, 2015
6IP3
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BU of 6ip3 by Molmil
Structure of human telomeric DNA at 1.4 Angstroms resolution
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), POTASSIUM ION
著者Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I.
登録日2018-11-01
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
6IPA
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BU of 6ipa by Molmil
C-terminal EMAP II-like domain of p43 refined against twinned data
分子名称: aminoacyl-tRNA synthetase-interacting multifunctional protein p43
著者Manickam, Y, Harlos, K, Gupta, S, Sharma, A.
登録日2018-11-02
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.
Acta Crystallogr D Struct Biol, 76, 2020
4MK7
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BU of 4mk7 by Molmil
Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 2 (3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one)
分子名称: 3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
著者Harris, S.F, Wong, A.
登録日2013-09-04
公開日2013-10-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B.
J.Med.Chem., 56, 2013
4XFE
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BU of 4xfe by Molmil
Crystal structure of a TRAP periplasmic solute binding protein from Pseudomonas putida F1 (Pput_1203), Target EFI-500184, with bound D-glucuronate
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, SULFATE ION, TRAP dicarboxylate transporter subunit DctP, ...
著者Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2014-12-26
公開日2015-01-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a TRAP periplasmic solute binding protein from Pseudomonas putida F1 (Pput_1203), Target EFI-500184, with bound D-glucuronate
To be published
6AWA
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BU of 6awa by Molmil
1.83 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD and Adenosine-5'-monophosphate.
分子名称: ADENOSINE MONOPHOSPHATE, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-09-05
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献1.83 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD and Adenosine-5'-monophosphate.
To Be Published
6IDM
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BU of 6idm by Molmil
Crystal structure of Peptidoglycan recognition protein (PGRP-S) with Tartaric acid at 3.20 A resolution
分子名称: L(+)-TARTARIC ACID, Peptidoglycan recognition protein 1
著者Bairagya, H.R, Shokeen, A, Sharma, P, Singh, P.K, Sharma, S, Singh, T.P.
登録日2018-09-10
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of Peptidoglycan recognition protein (PGRP-S) with Tartaric acid at 3.20 A resolution
To Be Published
4XIH
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Crystal structure of the R116A mutant AhpE from Mycobacterium tuberculosis
分子名称: AhpC/TSA family protein
著者Tamu Dufe, V, van Molle, I, Pallo, A, Messens, J.
登録日2015-01-07
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The active site architecture in peroxiredoxins: a case study on Mycobacterium tuberculosis AhpE.
Chem.Commun.(Camb.), 52, 2016
6ANF
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Design of a short thermo-stable alpha-helix embedded in a macrocycle
分子名称: 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide
著者Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F.
登録日2017-08-13
公開日2018-02-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle.
Chembiochem, 19, 2018
6AR2
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Structure of human SLMAP FHA domain in complex with pMST2
分子名称: ASP-GLY-TPO-MET-LYS-ARG, Sarcolemmal membrane-associated protein
著者Osinski, A, Ni, L, Luo, X.
登録日2017-08-21
公開日2018-07-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017

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