7C9K
 
 | | Crystal Structure of E84Q mutant of CntL in complex with SAM | | 分子名称: | CALCIUM ION, D-histidine 2-aminobutanoyltransferase, S-ADENOSYLMETHIONINE | | 著者 | Luo, Z, Zhou, H. | | 登録日 | 2020-06-06 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural insights into the ligand recognition and catalysis of the key aminobutanoyltransferase CntL in staphylopine biosynthesis.
Faseb J., 35, 2021
|
|
7DOR
 | |
7DPR
 | |
7DPS
 | |
7DQH
 | |
7DQI
 | | E. coli GyrB ATPase domain in complex with Esculetin | | 分子名称: | 1H-benzimidazol-2-amine, 6,7-bis(oxidanyl)chromen-2-one, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-23 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
|
|
7DQJ
 | | E. coli GyrB ATPase domain in complex with 3,4-Dihydroxyacetophenone | | 分子名称: | 1-[3,4-bis(oxidanyl)phenyl]ethanone, 1H-benzimidazol-2-amine, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
|
|
7DQF
 | |
7DQU
 | |
7DQL
 | | E. coli GyrB ATPase domain in complex with 4-chlorobenzene-1,2-diol | | 分子名称: | 1H-benzimidazol-2-amine, 4-CHLOROBENZENE-1,2-DIOL, DNA gyrase subunit B, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
|
|
7DQM
 | | E. coli GyrB ATPase domain in complex with Naringenin | | 分子名称: | 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... | | 著者 | Yu, Y, Zhou, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Identification of new building blocks by fragment screening for discovering GyrB inhibitors.
Bioorg.Chem., 114, 2021
|
|
7DQS
 | |
7DQW
 | |
7DKH
 | | Crystal structure of the Ctr9/Paf1/Cdc73/Rtf1 quaternary complex | | 分子名称: | Cell division control protein 73, RNA polymerase II-associated protein 1, RNA polymerase-associated protein CTR9, ... | | 著者 | Chen, F.L, Liu, B.B, Guo, L, Li, D.F, Zhou, H, Long, J.F. | | 登録日 | 2020-11-24 | | 公開日 | 2021-11-24 | | 最終更新日 | 2022-01-05 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of the Core Module of the Yeast Paf1 Complex.
J.Mol.Biol., 434, 2021
|
|
7EDR
 | |
7EIV
 | | heterotetrameric glycyl-tRNA synthetase from Escherichia coli | | 分子名称: | GLYCINE, Glycine--tRNA ligase alpha subunit, Glycine--tRNA ligase beta subunit, ... | | 著者 | Ju, Y, Zhou, H. | | 登録日 | 2021-03-31 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications.
Nucleic Acids Res., 49, 2021
|
|
7VRC
 | |
7D5C
 | | IleRS in complex with a tRNA site inhibitor | | 分子名称: | (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid, 1,2-ETHANEDIOL, Isoleucine--tRNA ligase, ... | | 著者 | Chen, B, Luo, S, Zhou, H. | | 登録日 | 2020-09-25 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | Inhibitory mechanism of reveromycin A at the tRNA binding site of a class I synthetase.
Nat Commun, 12, 2021
|
|
6B5Q
 | | DCN1 bound to 38 | | 分子名称: | DCN1-like protein 1, Peptidomimetic Inhibitors DI-591, TRIETHYLENE GLYCOL | | 著者 | Stuckey, J. | | 登録日 | 2017-09-29 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction.
J. Med. Chem., 61, 2018
|
|
5UFI
 | | DCN1 bound to DI-591 | | 分子名称: | DCN1-like protein 1, N-[(1S)-1-cyclohexyl-2-{[3-(morpholin-4-yl)propanoyl]amino}ethyl]-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide | | 著者 | Stuckey, J. | | 登録日 | 2017-01-04 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation.
Nat Commun, 8, 2017
|
|
3DXX
 | | Crystal structure of EcTrmB | | 分子名称: | GLYCEROL, tRNA (guanine-N(7)-)-methyltransferase | | 著者 | Zhou, H.H, Liu, Q, Gao, Y.X, Teng, M.K, Niu, L.W. | | 登録日 | 2008-07-25 | | 公開日 | 2009-05-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Proteins, 76, 2009
|
|
3DXZ
 | | Crystal structure of EcTrmB in complex with SAH | | 分子名称: | 1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Zhou, H.H, Liu, Q, Gao, Y.X, Teng, M.K, Niu, L.W. | | 登録日 | 2008-07-25 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Proteins, 76, 2009
|
|
3DXY
 | | Crystal structure of EcTrmB in complex with SAM | | 分子名称: | GLYCEROL, S-ADENOSYLMETHIONINE, SULFATE ION, ... | | 著者 | Zhou, H.H, Liu, Q, Gao, Y.X, Teng, M.K, Niu, L.W. | | 登録日 | 2008-07-25 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Monomeric tRNA (m(7)G46) methyltransferase from Escherichia coli presents a novel structure at the function-essential insertion
Proteins, 76, 2009
|
|
2Q6J
 | | Crystal Structure of Estrogen Receptor alpha Complexed to a B-N Substituted Ligand | | 分子名称: | 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL, Estrogen receptor, GRIP peptide | | 著者 | Zhou, H, Nettles, K.W, Bruning, J.B, Kim, Y, Joachimiak, A, Sharma, S, Carlson, K.E, Stossi, F, Katzenellenbogen, B.S, Greene, G.L, Katzenellenbogen, J.A. | | 登録日 | 2007-06-05 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands
Chem.Biol., 14, 2007
|
|
3SME
 | | Structure of PTP1B inactivated by H2O2/bicarbonate | | 分子名称: | MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Tanner, J.J, Singh, H. | | 登録日 | 2011-06-27 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases.
J.Am.Chem.Soc., 133, 2011
|
|
