6B5Q
DCN1 bound to 38
Summary for 6B5Q
Entry DOI | 10.2210/pdb6b5q/pdb |
Related PRD ID | PRD_002285 |
Descriptor | DCN1-like protein 1, Peptidomimetic Inhibitors DI-591, TRIETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | e3 ligase, complex, ligase-inhibitor complex, ligase, ligase/inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q96GG9 |
Total number of polymer chains | 4 |
Total formula weight | 54254.76 |
Authors | Stuckey, J. (deposition date: 2017-09-29, release date: 2018-02-28, Last modification date: 2023-11-15) |
Primary citation | Zhou, H.,Zhou, W.,Zhou, B.,Liu, L.,Chern, T.R.,Chinnaswamy, K.,Lu, J.,Bernard, D.,Yang, C.Y.,Li, S.,Wang, M.,Stuckey, J.,Sun, Y.,Wang, S. High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J. Med. Chem., 61:1934-1950, 2018 Cited by PubMed: 29438612DOI: 10.1021/acs.jmedchem.7b01455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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