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3N2N
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BU of 3n2n by Molmil
The Crystal Structure of Tumor Endothelial Marker 8 (TEM8) extracellular domain
分子名称: ACETATE ION, Anthrax toxin receptor 1, MAGNESIUM ION
著者Fu, S, Tong, X.H, Wu, Y, Li, Y.Y, Rao, Z.H.
登録日2010-05-18
公開日2011-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin.
Plos One, 5, 2010
6ACZ
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BU of 6acz by Molmil
The structure of CVA10 virus A-particle from its complex with Fab 2G8
分子名称: VP1, VP2, VP3
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6ACY
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BU of 6acy by Molmil
The structure of CVA10 virus A-particle
分子名称: VP1, VP2, VP3
著者Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6PLK
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BU of 6plk by Molmil
Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII
分子名称: Env, ZIKV-116 heavy chain, ZIKV-116 light chain
著者Zhao, H, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-07-01
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge.
J.Exp.Med., 217, 2020
5W4U
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BU of 5w4u by Molmil
Pol II elongation complex with an N6-methyladenine-containing template
分子名称: 14mer non-template DNA, 29mer template DNA, 9mer RNA, ...
著者Wang, W, Wang, D.
登録日2017-06-13
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
5W51
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BU of 5w51 by Molmil
Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP
分子名称: 14mer non-template DNA, 29mer template DNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
著者Wang, W, Wang, D.
登録日2017-06-13
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.404 Å)
主引用文献Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
8H77
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BU of 8h77 by Molmil
Hsp90-AhR-p23-XAP2 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ...
著者Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F.
登録日2022-10-19
公開日2023-01-04
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
5WE8
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BU of 5we8 by Molmil
Crystal structure of WNK1 in complex with N-{(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-N-methylquinoline-4-carboxamide (compound 8)
分子名称: MANGANESE (II) ION, N-{(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl}-2-(3-methoxyphenyl)-N-methylquinoline-4-carboxamide, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Xie, X, Kohls, D.
登録日2017-07-07
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models.
J. Med. Chem., 60, 2017
5WDY
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BU of 5wdy by Molmil
Crystal structure of WNK1 in complex with 1-cyclohexyl-N-({6-fluoro-1-[2-(3-methoxyphenyl)pyridin-4-yl]-1H-indol-3-yl}methyl)methanamine (compound 6)
分子名称: 1-cyclohexyl-N-({6-fluoro-1-[2-(3-methoxyphenyl)pyridin-4-yl]-1H-indol-3-yl}methyl)methanamine, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Xie, X, Kohls, D.
登録日2017-07-06
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.458 Å)
主引用文献Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models.
J. Med. Chem., 60, 2017
3LL4
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BU of 3ll4 by Molmil
Structure of the H13A mutant of Ykr043C in complex with fructose-1,6-bisphosphate
分子名称: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), Uncharacterized protein YKR043C
著者Singer, A, Xu, X, Cui, H, Dong, A, Stogios, P.J, Edwards, A.M, Joachimiak, A, Savchenko, A, Yakunin, A.F, Midwest Center for Structural Genomics (MCSG)
登録日2010-01-28
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.
J.Biol.Chem., 285, 2010
3LG2
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BU of 3lg2 by Molmil
A Ykr043C/ fructose-1,6-bisphosphate product complex following ligand soaking
分子名称: PHOSPHATE ION, Uncharacterized protein YKR043C
著者Singer, A, Xu, X, Cui, H, Dong, A, Edwards, A.M, Joachimiak, A, Yakunin, A.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-01-19
公開日2010-03-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.
J.Biol.Chem., 285, 2010
3F3K
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BU of 3f3k by Molmil
The structure of uncharacterized protein YKR043C from Saccharomyces cerevisiae.
分子名称: GLYCEROL, Uncharacterized protein YKR043C
著者Cuff, M, Xu, X, Cui, H, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-10-30
公開日2008-12-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.
J.Biol.Chem., 285, 2010
5YOV
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BU of 5yov by Molmil
Crystal structure of BRD4-BD1 bound with hjp126
分子名称: (3~{R})-4-cyclopentyl-~{N}-(2,4-dimethylphenyl)-1,3-dimethyl-2-oxidanylidene-3~{H}-quinoxaline-6-carboxamide, Bromodomain-containing protein 4
著者Xiong, B, Hu, J, Li, Y, Cao, D.
登録日2017-10-31
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups.
Eur.J.Med.Chem., 150, 2018
3NGB
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BU of 3ngb by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 gp120
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, T, Kwong, P.D.
登録日2010-06-11
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Science, 329, 2010
6ACU
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BU of 6acu by Molmil
The structure of CVA10 virus mature virion
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-27
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6ACW
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BU of 6acw by Molmil
The structure of CVA10 virus procapsid particle
分子名称: VP0, VP1, VP3
著者Zhu, R, Xu, L.F, Zheng, Q.B, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-27
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AD1
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BU of 6ad1 by Molmil
The structure of CVA10 procapsid from its complex with Fab 2G8
分子名称: VP0, VP1, VP3
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
6AD0
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BU of 6ad0 by Molmil
The structure of CVA10 mature virion in complex with Fab 2G8
分子名称: SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ...
著者Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T.
登録日2018-07-28
公開日2018-11-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
7BP3
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BU of 7bp3 by Molmil
Cryo-EM structure of the human MCT2
分子名称: Monocarboxylate transporter 2
著者Zhang, B, Jin, Q, Zhang, X, Guo, J, Ye, S.
登録日2020-03-21
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cooperative transport mechanism of human monocarboxylate transporter 2.
Nat Commun, 11, 2020
6M68
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BU of 6m68 by Molmil
The Cryo-EM Structure of Human Pannexin 1 in the Presence of CBX
分子名称: Pannexin-1
著者Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S.
登録日2020-03-13
公開日2020-04-15
最終更新日2020-05-13
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
6M66
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BU of 6m66 by Molmil
The Cryo-EM Structure of Human Pannexin 1
分子名称: Pannexin-1
著者Jin, Q, Bo, Z, Xiang, Z, Xiaokang, Z, Ye, S.
登録日2020-03-13
公開日2020-04-15
最終更新日2020-05-13
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structures of human pannexin 1 channel.
Cell Res., 30, 2020
6O7G
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BU of 6o7g by Molmil
Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
分子名称: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2019-03-07
公開日2019-05-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
8JZU
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BU of 8jzu by Molmil
SLC15A4_TASL complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
8JZS
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BU of 8jzs by Molmil
Outward-facing SLC15A4 dimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023
8JZR
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BU of 8jzr by Molmil
Outward_facing SLC15A4 monomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag
著者Zhang, S.S, Chen, X.D, Xie, M.
登録日2023-07-06
公開日2023-09-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling.
Nat Commun, 14, 2023

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