6QX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qx3 by Molmil](/molmil-images/mine/6qx3) | Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 | 分子名称: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | 登録日 | 2019-03-07 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
|
|
6RR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rr7 by Molmil](/molmil-images/mine/6rr7) | Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | 登録日 | 2019-05-17 | 公開日 | 2019-09-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
|
|
4M3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m3j by Molmil](/molmil-images/mine/4m3j) | Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis | 分子名称: | Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION | 著者 | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | 登録日 | 2013-08-06 | 公開日 | 2014-08-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
|
|
4N1H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n1h by Molmil](/molmil-images/mine/4n1h) | Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis | 分子名称: | Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N | 著者 | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | 登録日 | 2013-10-04 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
|
|
4M3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m3k by Molmil](/molmil-images/mine/4m3k) | Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis | 分子名称: | Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S | 著者 | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | 登録日 | 2013-08-06 | 公開日 | 2014-08-06 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
|
|
6QNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qnw by Molmil](/molmil-images/mine/6qnw) | |
8FD1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fd1 by Molmil](/molmil-images/mine/8fd1) | Crystal structure of photoactivated rhodopsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4.25 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
|
|
8FD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fd0 by Molmil](/molmil-images/mine/8fd0) | Crystal structure of bovine rod opsin in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb2, ... | 著者 | Salom, D, Palczewski, K, Kiser, P.D. | 登録日 | 2022-12-01 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.71 Å) | 主引用文献 | Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nat Commun, 14, 2023
|
|
4GGN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ggn by Molmil](/molmil-images/mine/4ggn) | Malaria invasion machinery protein complex | 分子名称: | Myosin A tail domain interacting protein MTIP, Myosin-A | 著者 | Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J. | 登録日 | 2012-08-06 | 公開日 | 2013-07-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody. Mol.Biochem.Parasitol., 190, 2013
|
|
7APJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7apj by Molmil](/molmil-images/mine/7apj) | Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation | 分子名称: | NB41, RAC-alpha serine/threonine-protein kinase,Non-specific serine/threonine protein kinase,RAC-alpha serine/threonine-protein kinase | 著者 | Truebestein, L, Hornegger, H, Leonard, T.A. | 登録日 | 2020-10-16 | 公開日 | 2021-08-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of autoinhibited Akt1 reveals mechanism of PIP 3 -mediated activation. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3OSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oss by Molmil](/molmil-images/mine/3oss) | The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system | 分子名称: | CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ... | 著者 | Korotkov, K.V, Pruneda, J, Hol, W.G.J. | 登録日 | 2010-09-09 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural and functional studies on the interaction of GspC and GspD in the type II secretion system. Plos Pathog., 7, 2011
|
|
6VI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vi4 by Molmil](/molmil-images/mine/6vi4) | Nanobody-Enabled Monitoring of Kappa Opioid Receptor States | 分子名称: | (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CHOLESTEROL, Kappa opioid receptor, ... | 著者 | Che, T, Roth, B.L. | 登録日 | 2020-01-11 | 公開日 | 2020-03-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun, 11, 2020
|
|
5VAQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vaq by Molmil](/molmil-images/mine/5vaq) | |
5VAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5van by Molmil](/molmil-images/mine/5van) | Crystal Structure of Beta-Klotho | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lee, S, Schlessinger, J. | 登録日 | 2017-03-27 | 公開日 | 2018-01-31 | 最終更新日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature, 553, 2018
|
|
5VAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vak by Molmil](/molmil-images/mine/5vak) | Crystal Structure of Beta-Klotho, Domain 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-klotho, ... | 著者 | Lee, S, Schlessinger, J. | 登録日 | 2017-03-27 | 公開日 | 2018-01-31 | 最終更新日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature, 553, 2018
|
|
7PQQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pqq by Molmil](/molmil-images/mine/7pqq) | |
7PQG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7pqg by Molmil](/molmil-images/mine/7pqg) | |
7Q1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q1u by Molmil](/molmil-images/mine/7q1u) | Structure of Hedgehog acyltransferase (HHAT) in complex with megabody 177 bound to non-hydrolysable palmitoyl-CoA (Composite Map) | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Megabody 177, ... | 著者 | Coupland, C, Carrique, L, Siebold, C. | 登録日 | 2021-10-21 | 公開日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure, mechanism, and inhibition of Hedgehog acyltransferase. Mol.Cell, 81, 2021
|
|
7Q6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q6z by Molmil](/molmil-images/mine/7q6z) | Structure of Hedgehog acyltransferase (HHAT) in complex with megabody 177 bound to IMP-1575 | 分子名称: | 2-(2-methylpropylamino)-1-[(4R)-4-(6-methylpyridin-2-yl)-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]ethanone, CHOLESTEROL, Megabody 177, ... | 著者 | Coupland, C, Carrique, L, Siebold, C. | 登録日 | 2021-11-09 | 公開日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structure, mechanism, and inhibition of Hedgehog acyltransferase. Mol.Cell, 81, 2021
|
|
3K81
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k81 by Molmil](/molmil-images/mine/3k81) | |
6B20
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b20 by Molmil](/molmil-images/mine/6b20) | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator | 分子名称: | CHLORIDE ION, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | 著者 | Gulati, S, Kiser, P.D, Palczewski, K. | 登録日 | 2017-09-19 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor. Nat Commun, 9, 2018
|
|
3K7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k7u by Molmil](/molmil-images/mine/3k7u) | Structure of essential protein from Trypanosoma brucei | 分子名称: | Antibody, MP18 RNA editing complex protein | 著者 | Wu, M. | 登録日 | 2009-10-13 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies. J.Struct.Biol., 174, 2011
|
|
3K80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k80 by Molmil](/molmil-images/mine/3k80) | Structure of essential protein from Trypanosoma brucei | 分子名称: | Antibody, MP18 RNA editing complex protein | 著者 | Wu, M. | 登録日 | 2009-10-13 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies. J.Struct.Biol., 174, 2011
|
|
3STB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3stb by Molmil](/molmil-images/mine/3stb) | A complex of two editosome proteins and two nanobodies | 分子名称: | MP18 RNA editing complex protein, RNA-editing complex protein MP42, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2011-07-09 | 公開日 | 2011-11-02 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody. Nucleic Acids Res., 40, 2012
|
|
7RTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rth by Molmil](/molmil-images/mine/7rth) | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab" | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fragment Antigen-Binding Heavy Chain, ... | 著者 | Filippova, E.V, Mukherjee, S, Bloch, J.S, Locher, K.P, Kossiakoff, A.A. | 登録日 | 2021-08-13 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|